{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T20:52:16Z","timestamp":1770151936132,"version":"3.49.0"},"reference-count":26,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T00:00:00Z","timestamp":1770076800000},"content-version":"vor","delay-in-days":3077,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>A 6-year old male neutered Scottish Terrier was referred with a 1 week history of progressive lethargy and anorexia. Neurological examination localized a lesion to the forebrain and hormonal testing showed panhypopituitarism. Magnetic resonance imaging (MRI) of the brain revealed a rounded, well-defined, suprasellar central mass. The mass was slightly hyperintense to the cortical grey matter on T2-weighted (T2W), hypointense on T1-weighted (T1W) images and without T2* signal void. There was a central fusiform enhancement of the mass after contrast administration which raised the suspicion of a pituitary neoplasm. Rapid deterioration of the dog prevented further clinical investigations. Histopathologic examination revealed a lymphocytic panhypophysitis of unknown origin suspected autoimmune involving the hypothalamus (hypothalamitis). This is a unique case report of a dog presenting with inflammatory hypophysitis and hypothalamitis of suspected autoimmune origin with detailed clinical, MRI, histology and immunohistochemistry findings.<\/jats:p>","DOI":"10.1111\/jvim.14790","type":"journal-article","created":{"date-parts":[[2017,7,26]],"date-time":"2017-07-26T12:18:36Z","timestamp":1501071516000},"page":"1527-1532","source":"Crossref","is-referenced-by-count":7,"title":["Hypophysitis, Panhypopituitarism, and Hypothalamitis in a Scottish Terrier Dog"],"prefix":"10.1093","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6781-3300","authenticated-orcid":false,"given":"L.","family":"Polledo","sequence":"first","affiliation":[{"name":"Veterinary Medicine and Science, University of Nottingham Pathology Department, , Nottingham,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Pride Veterinary Centre , Derby,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Adamany","sequence":"additional","affiliation":[{"name":"Pride Veterinary Centre , Derby,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Graham","sequence":"additional","affiliation":[{"name":"Veterinary Medicine and Science, University of Nottingham Pathology Department, , Nottingham,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Baiker","sequence":"additional","affiliation":[{"name":"Veterinary Medicine and Science, University of Nottingham Pathology Department, , Nottingham,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2017,9,1]]},"reference":[{"key":"2026020303214254300_jvim14790-bib-0001","first-page":"1074","article-title":"The Endocrine System. 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