{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T16:45:41Z","timestamp":1770223541965,"version":"3.49.0"},"reference-count":25,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T00:00:00Z","timestamp":1770076800000},"content-version":"vor","delay-in-days":2955,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>A 5-year-old male castrated Lhasa Apso cross was evaluated for a 1-month history of inappetence, lethargy, gagging, and progressive right thoracic limb lameness. Synovial fluid analysis revealed nonseptic suppurative inflammation, and a diagnosis of immune-mediated polyarthritis (IMPA) was made. After 3\u00a0months of treatment with prednisone and later cyclosporine, the dog developed multiple firm cutaneous and subcutaneous masses and a focal mass within the jejunum. Cultures of blood, urine, skin lesions, and the jejunal mass identified Nocardia veterana by matrix-absorption laser desorption ionization-time-of-flight mass spectrometry (MALDI-TOF MS) and allowed for earlier identification of the organism compared to more traditional secA1 gene sequencing. Immunosuppressive drug treatment was discontinued, and the dog was treated for 3\u00a0months by administration of trimethoprim-sulfamethoxazole (TMS). No recurrence of clinical signs was reported 1\u00a0year later. This case report highlights the clinical utility of MALDI-TOF MS, particularly for the rapid identification of slow-growing, fastidious organisms.<\/jats:p>","DOI":"10.1111\/jvim.14855","type":"journal-article","created":{"date-parts":[[2017,11,4]],"date-time":"2017-11-04T07:26:34Z","timestamp":1509780394000},"page":"418-422","source":"Crossref","is-referenced-by-count":11,"title":["Successful Treatment of Disseminated Nocardiosis Caused by Nocardia veterana in a Dog"],"prefix":"10.1093","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5603-677X","authenticated-orcid":false,"given":"S.","family":"Yaemsiri","sequence":"first","affiliation":[{"name":"Veterinary Medical Teaching Hospital, University of California-Davis , Davis, CA"},{"name":"Veterinary Specialty Hospitals of the Carolinas , 6405 Tryon Road, Cary, NC, 27518"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.E.","family":"Sykes","sequence":"additional","affiliation":[{"name":"University of California-Davis Department of Medicine & Epidemiology, , Davis, CA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2018,1,1]]},"reference":[{"key":"2026020303245173500_jvim14855-bib-0001","doi-asserted-by":"crossref","first-page":"2760","DOI":"10.1128\/JCM.00155-06","article-title":"Analysis of secA1 gene sequences for identification of Nocardia species","volume":"44","author":"Conville","year":"2006","journal-title":"J Clin Microbiol"},{"key":"2026020303245173500_jvim14855-bib-0002","doi-asserted-by":"crossref","first-page":"e102","DOI":"10.1111\/vde.12046","article-title":"Cutaneous nocardiosis in two dogs receiving ciclosporin therapy for the management of canine atopic dermatitis","volume":"24","author":"Siak","year":"2013","journal-title":"Vet Dermatol"},{"key":"2026020303245173500_jvim14855-bib-0003","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.1111\/jvim.12419","article-title":"Vertebral osteomyelitis and multiple cutaneous lesions in a dog caused by Nocardia pseudobrasiliensis","volume":"28","author":"Hilligas","year":"2014","journal-title":"J Vet Intern Med"},{"key":"2026020303245173500_jvim14855-bib-0004","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1099\/00207713-51-3-933","article-title":"Nocardia veterana sp. nov., isolated from human bronchial lavage","volume":"51","author":"G\u00fcrtler","year":"2001","journal-title":"Int J Syst Evol Microbiol"},{"key":"2026020303245173500_jvim14855-bib-0005","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1111\/j.1348-0421.2002.tb02713.x","article-title":"The first isolation of Nocardia veterana from a human mycetoma","volume":"46","author":"Kano","year":"2002","journal-title":"Microbiol Immunol"},{"key":"2026020303245173500_jvim14855-bib-0006","doi-asserted-by":"crossref","first-page":"2560","DOI":"10.1128\/JCM.41.6.2560-2568.2003","article-title":"Nocardia veterana as a pathogen in North American patients","volume":"41","author":"Conville","year":"2003","journal-title":"J Clin Microbiol"},{"key":"2026020303245173500_jvim14855-bib-0007","doi-asserted-by":"crossref","first-page":"1705","DOI":"10.1128\/JCM.41.4.1705-1709.2003","article-title":"Nocardia veterana, a new emerging pathogen","volume":"41","author":"Pottumarthy","year":"2003","journal-title":"J Clin Microbiol"},{"key":"2026020303245173500_jvim14855-bib-0008","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1128\/CMR.19.2.259-282.2006","article-title":"Clinical and laboratory features of the Nocardia spp. based on current molecular taxonomy","volume":"19","author":"Brown-Elliott","year":"2006","journal-title":"Clin Microbiol Rev"},{"key":"2026020303245173500_jvim14855-bib-0009","doi-asserted-by":"crossref","first-page":"5139","DOI":"10.1128\/JCM.42.11.5139-5145.2004","article-title":"Nocardia kruczakiae sp. nov., a pathogen in immunocompromised patients and a member of the \u201cN. nova Complex\u201d","volume":"42","author":"Conville","year":"2004","journal-title":"J Clin Microbiol"},{"key":"2026020303245173500_jvim14855-bib-0010","doi-asserted-by":"crossref","first-page":"3366","DOI":"10.1128\/JCM.00780-15","article-title":"Identification of Nocardia species by matrix-assisted laser desorption ionization\u2013time of flight mass spectrometry","volume":"53","author":"Khot","year":"2015","journal-title":"J Clin Microbiol"},{"key":"2026020303245173500_jvim14855-bib-0011","doi-asserted-by":"crossref","first-page":"4015","DOI":"10.1128\/JCM.01234-10","article-title":"Evaluation of matrix-assisted laser desorption ionization-time of flight mass spectrometry for identification of Nocardia species","volume":"48","author":"Verroken","year":"2010","journal-title":"J Clin Microbiol"},{"key":"2026020303245173500_jvim14855-bib-0012","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1128\/JCM.02942-15","article-title":"Multicenter matrix-assisted laser desorption ionization-time of flight mass spectrometry study for identification of clinically relevant Nocardia spp","volume":"54","author":"Blosser","year":"2016","journal-title":"J Clin Microbiol"},{"key":"2026020303245173500_jvim14855-bib-0013","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/j.bjm.2016.01.029","article-title":"Clinical significance, antimicrobial susceptibility and molecular identification of Nocardia species isolated from children with cystic fibrosis","volume":"47","author":"Betran","year":"2016","journal-title":"Braz J Microbiol"},{"key":"2026020303245173500_jvim14855-bib-0014","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.bjid.2014.11.003","article-title":"Nocardia veterana: Disseminated infection with urinary tract infection","volume":"19","author":"Poisnel","year":"2015","journal-title":"Braz J Infect Dis"},{"key":"2026020303245173500_jvim14855-bib-0015","doi-asserted-by":"crossref","first-page":"306","DOI":"10.3109\/00313021003633144","article-title":"Bowel abscess with Nocardia veterana associated with colon carcinoma","volume":"42","author":"Schlebusch","year":"2010","journal-title":"Pathology"},{"key":"2026020303245173500_jvim14855-bib-0016","doi-asserted-by":"crossref","first-page":"e48","DOI":"10.1111\/ajd.12043","article-title":"First case report of Nocardia veterana causing nodular lymphangitis in an immunocompromised host","volume":"55","author":"Dua","year":"2014","journal-title":"Australas J Dermatol"},{"key":"2026020303245173500_jvim14855-bib-0017","doi-asserted-by":"crossref","first-page":"4364","DOI":"10.1128\/JCM.01062-11","article-title":"First report of a brain abscess caused by Nocardia veterana","volume":"49","author":"Arends","year":"2011","journal-title":"J Clin Microbiol"},{"key":"2026020303245173500_jvim14855-bib-0018","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/j.ijid.2006.03.005","article-title":"Nocardia veterana bloodstream infection in a patient with cancer and a summary of reported cases","volume":"10","author":"Ansari","year":"2006","journal-title":"Int J Infect Dis"},{"key":"2026020303245173500_jvim14855-bib-0019","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1186\/1869-5760-3-44","article-title":"Nocardia veterana endogenous endophthalmitis in a cardiac transplant patient","volume":"3","author":"Scott","year":"2013","journal-title":"J Ophthalmic Inflamm Infect"},{"key":"2026020303245173500_jvim14855-bib-0020","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.vetmic.2015.12.001","article-title":"Fatal nocardiosis in a dog caused by multiresistant Nocardia veterana","volume":"183","author":"Uhde","year":"2013","journal-title":"Vet Microbiol"},{"key":"2026020303245173500_jvim14855-bib-0021","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1016\/j.vetmic.2013.08.019","article-title":"Molecular identification and antimicrobial susceptibility of Nocardia spp. isolated from bovine mastitis in Brazil","volume":"167","author":"Condas","year":"2013","journal-title":"Vet Microbiol"},{"key":"2026020303245173500_jvim14855-bib-0022","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1128\/CMR.7.2.213","article-title":"Nocardia species: Host-parasite relationships","volume":"7","author":"Beaman","year":"1994","journal-title":"Clin Microbiol Rev"},{"key":"2026020303245173500_jvim14855-bib-0023","doi-asserted-by":"crossref","first-page":"1776","DOI":"10.1128\/AAC.32.12.1776","article-title":"Antimicrobial susceptibility patterns of Nocardia asteroides","volume":"32","author":"Wallace","year":"1988","journal-title":"Antimicrob Agents Chemother"},{"key":"2026020303245173500_jvim14855-bib-0024","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1128\/AAC.01531-13","article-title":"Susceptibility profiles of Nocardia isolates based on current taxonomy","volume":"58","author":"Schlaberg","year":"2014","journal-title":"Antimicrob Agents Chemother"},{"key":"2026020303245173500_jvim14855-bib-0025","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1093\/clinids\/22.6.891","article-title":"Nocardiosis","volume":"22","author":"Lerner","year":"1996","journal-title":"Clin Infectious Diseases"}],"container-title":["Journal of Veterinary Internal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjvim.14855","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/jvim\/article-pdf\/32\/1\/418\/66672508\/jvim14855.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jvim\/article-pdf\/32\/1\/418\/66672508\/jvim14855.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T08:24:59Z","timestamp":1770107099000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jvim\/article\/32\/1\/418\/8449615"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1,1]]},"references-count":25,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,1,1]]}},"URL":"https:\/\/doi.org\/10.1111\/jvim.14855","relation":{},"ISSN":["1939-1676"],"issn-type":[{"value":"1939-1676","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2018,1]]},"published":{"date-parts":[[2018,1,1]]}}}