{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T16:44:27Z","timestamp":1770396267128,"version":"3.49.0"},"reference-count":25,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T00:00:00Z","timestamp":1770076800000},"content-version":"vor","delay-in-days":2835,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institute of Health","doi-asserted-by":"publisher","award":["S10 OD018056"],"award-info":[{"award-number":["S10 OD018056"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Thymoma-associated nephropathies have been reported in people but not in dogs. In this report, we describe a dog with thymoma and concurrent renal amyloidosis. A 7-year-old castrated male Weimaraner was presented for progressive anorexia, lethargy, and tachypnea. The dog was diagnosed with azotemia, marked proteinuria, and a thymoma that was surgically removed. Postoperatively, the dog developed a large left ventricular thrombus and was euthanized. Necropsy confirmed the presence of a left ventricular thrombus and histopathology revealed renal amyloidosis. We speculate that the renal amyloidosis occurred secondary to the thymoma, with amyloidosis in turn leading to nephrotic syndrome, hypercoagulability, and ventricular thrombosis. This case illustrates the potential for thymoma-associated nephropathies to occur in dogs and that dogs suspected to have thymoma should have a urinalysis and urine protein creatinine ratio performed as part of the pre-surgical database.<\/jats:p>","DOI":"10.1111\/jvim.15062","type":"journal-article","created":{"date-parts":[[2018,2,27]],"date-time":"2018-02-27T08:28:44Z","timestamp":1519720124000},"page":"1160-1165","source":"Crossref","is-referenced-by-count":3,"title":["Concurrent renal amyloidosis and thymoma resulting in a fatal ventricular thrombus in a dog"],"prefix":"10.1093","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9951-7151","authenticated-orcid":false,"given":"Jennifer M.","family":"Loewen","sequence":"first","affiliation":[{"name":"College of Veterinary Medicine, Iowa State University Department of Veterinary Clinical Sciences, ,Ames, Iowa"},{"name":"University of Wisconsin, College of Veterinary Medicine Department of Veterinary Clinical Sciences, , Madison, WI 53704"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rachel E.","family":"Cianciolo","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine, The Ohio State University Department of Veterinary Biosciences and International Veterinary Renal Pathology Service, ,Columbus, Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liwen","family":"Zhang","sequence":"additional","affiliation":[{"name":"Mass Spectrometry and Proteomics Facility, Campus Chemical Instrument Center, The Ohio State University ,Columbus, Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Yaeger","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine, Iowa State University Department of Veterinary Pathology, ,Ames, Iowa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9153-7916","authenticated-orcid":false,"given":"Jessica L.","family":"Ward","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine, Iowa State University Department of Veterinary Clinical Sciences, ,Ames, Iowa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jodi D.","family":"Smith","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine, Iowa State University Department of Veterinary Pathology, ,Ames, Iowa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1089-5640","authenticated-orcid":false,"given":"Dana N.","family":"LeVine","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine, Iowa State University Department of Veterinary Clinical Sciences, ,Ames, 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