{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T04:28:53Z","timestamp":1771475333022,"version":"3.50.1"},"reference-count":150,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T00:00:00Z","timestamp":1770076800000},"content-version":"vor","delay-in-days":2774,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2018,4,24]],"date-time":"2018-04-24T00:00:00Z","timestamp":1524528000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001280","name":"Horserace Betting Levy Board, United Kingdom","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001280","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001280","name":"Horserace Betting Levy Board","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001280","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2018,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Recurrent Laryngeal Neuropathy (RLN) is a highly prevalent and predominantly left-sided, degenerative disorder of the recurrent laryngeal nerves (RLn) of tall horses, that causes inspiratory stridor at exercise because of intrinsic laryngeal muscle paresis. The associated laryngeal dysfunction and exercise intolerance in athletic horses commonly leads to surgical intervention, retirement or euthanasia with associated financial and welfare implications. Despite speculation, there is a lack of consensus and conflicting evidence supporting the primary classification of RLN, as either a distal (\u201cdying back\u201d) axonopathy or as a primary myelinopathy and as either a (bilateral) mononeuropathy or a polyneuropathy; this uncertainty hinders etiological and pathophysiological research. In this review, we discuss the neuropathological changes and electrophysiological deficits reported in the RLn of affected horses, and the evidence for correct classification of the disorder. In so doing, we summarize and reveal the limitations of much historical research on RLN and propose future directions that might best help identify the etiology and pathophysiology of this enigmatic disorder.<\/jats:p>","DOI":"10.1111\/jvim.15142","type":"journal-article","created":{"date-parts":[[2018,4,25]],"date-time":"2018-04-25T00:10:58Z","timestamp":1524615058000},"page":"1397-1409","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Pathological classification of equine recurrent laryngeal neuropathy"],"prefix":"10.1093","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3766-919X","authenticated-orcid":false,"given":"Alexandra C. E.","family":"Draper","sequence":"first","affiliation":[{"name":"Comparative Neuromuscular Disease Laboratory , Department is Clinical Science and Services, Royal Veterinary College,London,","place":["United Kingdom"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard J.","family":"Piercy","sequence":"additional","affiliation":[{"name":"Comparative Neuromuscular Disease Laboratory , Department is Clinical Science and Services, Royal Veterinary College,London,","place":["United Kingdom"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2018,7,1]]},"reference":[{"key":"2026020303313233900_jvim15142-bib-0001","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1186\/1471-2164-15-259","article-title":"Genomic analysis establishes correlation between growth and laryngeal neuropathy in Thoroughbreds","volume":"15","author":"Boyko","year":"2014","journal-title":"BMC Genomics."},{"key":"2026020303313233900_jvim15142-bib-0002","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1080\/00480169.1985.35170","article-title":"Roaring in Clydesdales","volume":"33","author":"Goulden","year":"1985","journal-title":"N Z Vet J."},{"key":"2026020303313233900_jvim15142-bib-0003","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1080\/00480169.1986.35334","article-title":"Equine laryngeal hemiplegia. 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