{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T05:29:18Z","timestamp":1792042158741,"version":"4.4.0"},"reference-count":35,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T00:00:00Z","timestamp":1770076800000},"content-version":"vor","delay-in-days":2043,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2020,6,17]],"date-time":"2020-06-17T00:00:00Z","timestamp":1592352000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2020,7,1]]},"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n Obesity and insulin dysregulation (ID) predispose horses to laminitis. Determination of management practices or phenotypic markers associated with ID may benefit animal welfare.<\/jats:p>\n <\/jats:sec>\n \n Objectives<\/jats:title>\n Determine ID status of a population of Finnhorses using an oral sugar test (OST) and compare phenotypes and management factors between ID and non-ID Finnhorses.<\/jats:p>\n <\/jats:sec>\n \n Animals<\/jats:title>\n One hundred twenty-eight purebred Finnhorses \u22653\u2009years of age.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n Owners were recruited using an online questionnaire regarding signalment, history, feeding, and exercise of their horses. Selected contributing stables within a predefined area were visited. Phenotypic markers of obesity and the weight of each horse were recorded. After fasting overnight, horses received 0.45\u2009mL\/kg corn syrup PO. Serum samples before and at 60 and 90\u2009minutes after syrup administration were analyzed for insulin by chemiluminescent assay. Horses met ID criteria if insulin concentrations were \u226533\u2009\u03bcIU\/mL at T0, \u226566\u2009\u03bcIU\/mL at T60 or T90 or some combination thereof. Associations between phenotypic markers, feeding and exercise variables, and ID were examined using mixed effects logistic regression modeling.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n Several phenotypic markers of obesity were significant on univariable analysis but in the final multivariable model, only obesity (body condition score\u2009\u2009\u22658) was associated with ID (P = .04). Over half of the horses (60% [95% confidence interval (CI), 51%-68%]) were considered overweight or obese whereas 16% (95% CI, 10%-23%) were classified as having ID.<\/jats:p>\n <\/jats:sec>\n \n Conclusions and Clinical Importance<\/jats:title>\n Because obesity is associated with ID in cold-blooded type horses, objective monitoring of phenotypic markers by owners may be beneficial for health outcomes.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/jvim.15782","type":"journal-article","created":{"date-parts":[[2020,6,17]],"date-time":"2020-06-17T05:48:50Z","timestamp":1592372930000},"page":"1599-1605","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Insulin dysregulation in a population of Finnhorses and associated phenotypic markers of obesity"],"prefix":"10.1093","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8527-6556","authenticated-orcid":false,"given":"Justin 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