{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T13:27:25Z","timestamp":1790342845187,"version":"4.1.0"},"reference-count":146,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T00:00:00Z","timestamp":1770076800000},"content-version":"vor","delay-in-days":1678,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2021,6,3]],"date-time":"2021-06-03T00:00:00Z","timestamp":1622678400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Fonds de Recherche du Qu\u00e9bec en Sant\u00e9","award":["272483"],"award-info":[{"award-number":["272483"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Despite substantial research efforts to improve the treatment and outcome of horses with asthma, glucocorticoids (GC) remain the cornerstone of drug treatment of this prevalent disease. The high efficacy of GC to relieve airway obstruction explains their extensive use despite potential deleterious effects. However, much is yet to be uncovered concerning GC use in horses with asthma, including the comparative efficacy of the different drugs, the determination of minimal effective doses and the mechanisms underlying their variable modulation of airway inflammation. The objectives of this structured review were to report and compare the plethora of effects of the various GC used in asthmatic horses with a focus on impact on lung function, airway inflammation, and bronchial remodeling. Adverse effects are also briefly described, with an emphasis on those that have been specifically reported in horses with asthma. Ultimately, we aimed to highlight gaps in the literature and to identify future research areas.<\/jats:p>","DOI":"10.1111\/jvim.16189","type":"journal-article","created":{"date-parts":[[2021,6,4]],"date-time":"2021-06-04T08:56:41Z","timestamp":1622797001000},"page":"2045-2057","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Glucocorticoid treatment in horses with asthma: A narrative review"],"prefix":"10.1093","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4768-6674","authenticated-orcid":false,"given":"Sophie","family":"Mainguy-Seers","sequence":"first","affiliation":[{"name":"Faculty of Veterinary Medicine , Department of Clinical Sciences, Universit\u00e9 de Montr\u00e9al, St-Hyacinthe, Quebec,","place":["Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4655-2102","authenticated-orcid":false,"given":"Jean-Pierre","family":"Lavoie","sequence":"additional","affiliation":[{"name":"Faculty of Veterinary Medicine , Department of Clinical Sciences, Universit\u00e9 de Montr\u00e9al, St-Hyacinthe, Quebec,","place":["Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2021,7,1]]},"reference":[{"key":"2026020922180224300_jvim16189-bib-0001","doi-asserted-by":"crossref","first-page":"1635","DOI":"10.2460\/ajvr.67.9.1635","article-title":"Temporal clinical exacerbation of summer pasture-associated recurrent airway obstruction and relationship with climate and aeroallergens in horses","volume":"67","author":"Costa","year":"2006","journal-title":"Am J Vet 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