{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T01:31:07Z","timestamp":1788571867583,"version":"build-2803163510"},"reference-count":49,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T00:00:00Z","timestamp":1770076800000},"content-version":"vor","delay-in-days":1494,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2021,12,16]],"date-time":"2021-12-16T00:00:00Z","timestamp":1639612800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Open access funding enabled and organized by Projekt DEAL."}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Catheter-based occlusion of patent ductus arteriosus (PDA) can be performed using different devices. Transvenous embolization using the Amplatzer vascular plug II (AVP-II) has been studied in humans, but it has not been described in dogs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Evaluate the feasibility and success of transvenous embolization of PDA using the AVP-II in dogs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Animals<\/jats:title>\n                    <jats:p>Nineteen client-owned dogs with left-to-right shunting PDA, with minimal ductal diameter\u2009&amp;gt;2.5\u2009mm.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Prospective observational study using AVP-II with transvenous access for PDA closure in dogs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Angiography showed a conical ductus with a long (n\u00a0=\u00a017) or short (n\u00a0=\u00a02) ampulla. The minimal diameter of the duct was 4.34\u2009\u00b1\u20091.11\u2009mm, and the maximal diameter of the ampulla was 13.18\u2009\u00b1\u20093.47\u2009mm. Technical success was achieved in 18 of the 19 (94.7%) patients after the first intervention and in all 19 (100%) patients after the second intervention. Postrelease angiography documented complete occlusion of the PDA in 10 of 19 (52.6%) dogs. Mild flow acceleration or stenosis of the left pulmonary artery was found in 6 and 1 of the 17 analyzed cases, respectively, by Doppler examination. The closure rate 24\u2009hours after intervention was 94.7% (18\/19). The remaining dog had a moderate residual shunt, and delayed complete closure after 3\u00a0months led to a 100% closure rate.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion and Clinical Importance<\/jats:title>\n                    <jats:p>The AVP-II is a safe and effective device for transvenous embolization in dogs with moderate to large PDA.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jvim.16342","type":"journal-article","created":{"date-parts":[[2021,12,16]],"date-time":"2021-12-16T04:49:22Z","timestamp":1639630162000},"page":"20-28","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Transvenous embolization of moderate to large patent ductus arteriosus in dogs using the Amplatzer vascular plug II"],"prefix":"10.1093","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1555-9483","authenticated-orcid":false,"given":"Nicolai","family":"Hildebrandt","sequence":"first","affiliation":[{"name":"Small Animal Clinic (Internal Medicine), Justus-Liebig Universit\u00e4t Giessen , Giessen,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Stosic","sequence":"additional","affiliation":[{"name":"Small Animal Clinic (Internal Medicine), Justus-Liebig Universit\u00e4t Giessen , Giessen,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Estelle","family":"Henrich","sequence":"additional","affiliation":[{"name":"Small Animal Clinic (Internal Medicine), Justus-Liebig Universit\u00e4t Giessen , Giessen,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicola","family":"Wiedemann","sequence":"additional","affiliation":[{"name":"Small Animal Clinic (Internal 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