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Recently, serum symmetric dimethylarginine concentration was introduced as a novel glomerular filtration rate biomarker for the early detection of CKD in cats. However, data on its specificity are still limited. The limitations of conventional biomarkers and the desire for early therapeutic intervention in cats with CKD to improve outcomes have prompted the discovery and validation of novel renal biomarkers to detect glomerular or tubular dysfunction. Changes in the serum or urinary concentrations of these biomarkers may indicate early kidney damage or predict the progression of kidney before changes in conventional biomarkers are detectable. This review summarizes current knowledge on renal biomarkers in CKD in cats, a field that has progressed substantially over the last 5\u2009years.<\/jats:p>","DOI":"10.1111\/jvim.16377","type":"journal-article","created":{"date-parts":[[2022,2,26]],"date-time":"2022-02-26T07:39:19Z","timestamp":1645861159000},"page":"379-396","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":51,"title":["Renal biomarkers in cats: A review of the current status in chronic kidney disease"],"prefix":"10.1093","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3458-4978","authenticated-orcid":false,"given":"Thirawut","family":"Kongtasai","sequence":"first","affiliation":[{"name":"Small Animal Department, Faculty of Veterinary Science, Ghent University, Merelbeke,","place":["Belgium"]},{"name":"Faculty of Veterinary Science, Mahidol University Department of Clinical Sciences and Public Health, , Nakhon Pathom,","place":["Thailand"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominique","family":"Paepe","sequence":"additional","affiliation":[{"name":"Small Animal Department, Faculty of Veterinary Science, Ghent University, Merelbeke,","place":["Belgium"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evelyne","family":"Meyer","sequence":"additional","affiliation":[{"name":"Toxicology and Biochemistry, Faculty of Veterinary Medicine, Ghent University Department of Pharmacology, , Merelbeke,","place":["Belgium"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Femke","family":"Mortier","sequence":"additional","affiliation":[{"name":"Small Animal Department, Faculty of Veterinary Science, Ghent University, Merelbeke,","place":["Belgium"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sofie","family":"Marynissen","sequence":"additional","affiliation":[{"name":"Small Animal Department, Faculty of Veterinary Science, Ghent University, Merelbeke,","place":["Belgium"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Stammeleer","sequence":"additional","affiliation":[{"name":"Small Animal Department, Faculty of Veterinary Science, Ghent University, Merelbeke,","place":["Belgium"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pieter","family":"Defauw","sequence":"additional","affiliation":[{"name":"Lumbry Park Veterinary Specialists , Alton,","place":["United Kingdom"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sylvie","family":"Daminet","sequence":"additional","affiliation":[{"name":"Small Animal Department, Faculty of Veterinary Science, Ghent University, 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