{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T21:24:32Z","timestamp":1788470672327,"version":"build-2803163510"},"reference-count":40,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T00:00:00Z","timestamp":1770076800000},"content-version":"vor","delay-in-days":1435,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2022,2,15]],"date-time":"2022-02-15T00:00:00Z","timestamp":1644883200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Gallbladder mucocele (GBM) is a common biliary disorder in dogs that can be categorized into 6 types, but the value of this classification scheme remains unknown. Cholecystectomy is associated with high death rates and warrants additional interrogation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Investigate the clinical value of ultrasonographic diagnosis of type of GBM and identify prognostic factors in dogs with GBM undergoing cholecystectomy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Animals<\/jats:title>\n                    <jats:p>Two hundred sixteen dogs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Retrospective cohort study. Dogs with GBM diagnosed from 2014 to 2019 at 6 veterinary referral hospitals in Asia. Ultrasonogram images were reviewed and a GBM type (ie, types I-VI) assigned.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Dogs with GBM type V as compared to I (OR, 8.6; 95% CI, 2.6-27.8; P\u2009&amp;lt;\u2009.001) and III (OR, 10.0; 95% CI, 2.5-40.8; P\u00a0=\u00a0.001), and dogs with type VI compared to I (OR, 10.5; 95% CI, 1.8-61.2; P\u00a0=\u00a0.009) and III (OR, 12.3; 95% CI, 1.8-83.9; P\u00a0=\u00a0.01) were more likely to exhibit signs of biliary tract disease. Independent predictors of death after cholecystectomy included age (OR, 2.81; 95% CI, 1.41-5.59; P\u00a0=\u00a0.003) and intraoperative systolic blood pressure (SBP) nadir. There was an interaction between SBP nadir and gallbladder rupture; SBP nadir in dogs with (OR, 0.92; 95% CI, 0.89-0.94; P\u2009&amp;lt;\u2009.001) and without (OR, 0.88; 95% CI, 0.82-0.93; P\u2009&amp;lt;\u2009.001) gallbladder rupture.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion and Clinical Importance<\/jats:title>\n                    <jats:p>Increasing developmental stage of GBM could be associated with an increased likelihood of biliary tract related clinical signs. Nadir SBP deserves further investigation as a prognostic or potentially modifiable variable, particularly in the presence of gallbladder rupture.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jvim.16384","type":"journal-article","created":{"date-parts":[[2022,2,16]],"date-time":"2022-02-16T01:02:04Z","timestamp":1644973324000},"page":"565-575","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Ultrasonographic patterns, clinical findings, and prognostic variables in dogs from Asia with gallbladder mucocele"],"prefix":"10.1093","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0270-4728","authenticated-orcid":false,"given":"Jared A.","family":"Jaffey","sequence":"first","affiliation":[{"name":"Midwestern University College of Veterinary Medicine Department of Specialty Medicine, , Glendale, 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National Taiwan University , Taipei,","place":["Taiwan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5276-3179","authenticated-orcid":false,"given":"Chung-Hui","family":"Lin","sequence":"additional","affiliation":[{"name":"Graduate Institute of Veterinary Clinical Sciences, School of Veterinary Medicine, National Taiwan University , Taipei,","place":["Taiwan"]},{"name":"National Taiwan University Veterinary Hospital, National Taiwan University , Taipei,","place":["Taiwan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lawren L.","family":"Durocher-Babek","sequence":"additional","affiliation":[{"name":"Veterinary Specialty Hospital , Wan Chai,","place":["Hong Kong"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyoung-Won","family":"Seo","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine, Chungnam National University Department of Veterinary Internal Medicine, , 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