{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T00:37:04Z","timestamp":1788568624999,"version":"build-2803163510"},"reference-count":31,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T00:00:00Z","timestamp":1770076800000},"content-version":"vor","delay-in-days":1374,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2022,3,18]],"date-time":"2022-03-18T00:00:00Z","timestamp":1647561600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Beta-blockade is sometimes used in dogs with pulmonic stenosis with the intent of reducing frequency of ventricular arrhythmias during right heart catheterization.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To evaluate if pretreatment with atenolol reduces frequency of ventricular arrhythmias, anesthetist interventions, or shortens procedure time.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Animals<\/jats:title>\n                    <jats:p>Thirty dogs with pulmonic stenosis scheduled for interventional procedures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Single center, prospective, randomized, open-label study. Dogs were randomized to treatment with atenolol or no treatment preoperatively for a minimum of 10\u2009days. Variables recorded included heart rate, arrhythmias and complexity, total procedure time and administration of antiarrhythmic treatment, vasopressors, positive chronotropes, or fluid boluses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Fifteen dogs were enrolled in each group. Dogs receiving atenolol had lower mean heart rates during the procedure (atenolol 100\u2009\u00b1\u200911\u2009bpm vs untreated 115\u2009\u00b1\u200919\u2009bpm, P\u00a0=\u00a0.01). There were no significant differences between the atenolol and untreated groups in the frequency of ventricular ectopic complexes (535 [6-5296] vs 553 [79-2863], P\u00a0=\u00a0.9), ventricular couplets (46 [0-481] vs 29 [3-121], P\u00a0=\u00a0.59), ventricular triplets (20 [0-265] vs 16 [1-82], P\u00a0=\u00a0.67), ventricular tachycardia (8 [0-224] vs 8 [1-118], P\u00a0=\u00a0.99), proportion exhibiting R-on-T phenomenon (11\/15 vs 14\/15, P\u00a0=\u00a0.33), proportion receiving intraoperative lidocaine (1\/15 vs 3\/15, P\u00a0=\u00a0.6), vasopressors\/positive chronotropes (11\/15 vs 5\/15, P\u00a0=\u00a0.06), or fluid boluses (12\/15 vs 7\/15, P\u00a0=\u00a0.13). The procedure time was similar (atenolol 41 [23-68] min vs untreated 35 [18-98] min, P\u00a0=\u00a0.91).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions and Clinical Importance<\/jats:title>\n                    <jats:p>No benefit of preoperative atenolol treatment was identified in this small group of dogs.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jvim.16403","type":"journal-article","created":{"date-parts":[[2022,3,18]],"date-time":"2022-03-18T06:20:17Z","timestamp":1647584417000},"page":"877-885","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Effect of preoperative administration of atenolol to dogs with pulmonic stenosis undergoing interventional procedures"],"prefix":"10.1093","volume":"36","author":[{"given":"Samantha","family":"Gomart","sequence":"first","affiliation":[{"name":"Highcroft Veterinary Referrals, CVS Group , 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