{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T01:41:33Z","timestamp":1785462093078,"version":"3.56.0"},"reference-count":73,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T00:00:00Z","timestamp":1770076800000},"content-version":"vor","delay-in-days":1374,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2022,3,20]],"date-time":"2022-03-20T00:00:00Z","timestamp":1647734400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007825","name":"American College of Veterinary Internal Medicine","doi-asserted-by":"publisher","award":["Resident Fund"],"award-info":[{"award-number":["Resident Fund"]}],"id":[{"id":"10.13039\/100007825","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Companion Animal Research Fund"},{"name":"Winkelman Family Fund in Cardiovascular Research"},{"DOI":"10.13039\/100007825","name":"American College of Veterinary Internal Medicine","doi-asserted-by":"publisher","award":["Resident Fund"],"award-info":[{"award-number":["Resident Fund"]}],"id":[{"id":"10.13039\/100007825","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Treatment for Boxers with ventricular tachycardia (VT) is limited. Electroanatomic mapping (EAM) facilitates identification of arrhythmogenic substrate for radiofrequency catheter ablation (RFCA).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Describe the use of EAM to guide RFCA in Boxers with VT.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Animals<\/jats:title>\n                    <jats:p>Five client-owned Boxers with symptomatic VT or persistent VT despite antiarrhythmic medications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Case series evaluating clinical, EAM, and before and after RFCA Holter data.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Sustained VT was inducible in 3 dogs, but required aggressive stimulation protocols. Low-voltage areas consistent with electroanatomic scar were found in 2 dogs, located at the right ventricular (RV) outflow tract and cranial RV. Two dogs had a focal activation pattern of VT and 1 dog had a reentrant mechanism. After RFCA, all dogs no longer collapsed and had fewer runs of VT, 3 of which had 0 runs of VT. Number of ventricular premature beats increased in 3 dogs and decreased in 2 dogs, 1 of which had nearly complete resolution of all arrhythmias. Procedural complications included ventricular fibrillation (n\u00a0=\u00a02) with successful defibrillation, bruising or hemorrhage at the vascular access site (n\u00a0=\u00a04), retroperitoneal hemorrhage (n\u00a0=\u00a01), aortic and mitral regurgitation (n\u00a0=\u00a01), onset of frequent supraventricular tachycardia (n\u00a0=\u00a01), and persistent right pelvic limb lameness (n\u00a0=\u00a01).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions and Clinical Importance<\/jats:title>\n                    <jats:p>Electroanatomic mapping and RFCA are feasible in Boxers with VT. Based on this small cohort, RFCA may help decrease runs of VT and improve clinical signs. The anatomic substrate and electrophysiologic mechanisms are variable and require further study.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jvim.16412","type":"journal-article","created":{"date-parts":[[2022,3,21]],"date-time":"2022-03-21T02:20:51Z","timestamp":1647829251000},"page":"886-896","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Feasibility of electroanatomic mapping and radiofrequency catheter ablation in Boxer dogs with symptomatic ventricular tachycardia"],"prefix":"10.1093","volume":"36","author":[{"given":"Alexandra V.","family":"Crooks","sequence":"first","affiliation":[{"name":"School of Veterinary Medicine, University of Pennsylvania Department of Clinical Sciences and Advanced Medicine, , Philadelphia, Pennsylvania,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2972-0760","authenticated-orcid":false,"given":"Weihow","family":"Hsue","sequence":"additional","affiliation":[{"name":"School of Veterinary Medicine, University of Pennsylvania Department of Clinical Sciences and Advanced Medicine, , Philadelphia, Pennsylvania,","place":["USA"]},{"name":"Cardiac Electrophysiology Section, Division of Cardiovascular Medicine, Hospital of the University of Pennsylvania , Philadelphia, Pennsylvania,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cory M.","family":"Tschabrunn","sequence":"additional","affiliation":[{"name":"Cardiac Electrophysiology Section, Division of Cardiovascular Medicine, Hospital of the University of Pennsylvania , Philadelphia, Pennsylvania,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7997-5374","authenticated-orcid":false,"given":"Anna R.","family":"Gelzer","sequence":"additional","affiliation":[{"name":"School of Veterinary Medicine, University of Pennsylvania Department of Clinical Sciences and Advanced Medicine, , Philadelphia, Pennsylvania,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,5,1]]},"reference":[{"key":"2026020303580284000_jvim16412-bib-0001","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.jvc.2011.03.002","article-title":"Ultrastructural changes in cardiac myocytes from Boxer dogs with arrhythmogenic right ventricular cardiomyopathy","volume":"13","author":"Oxford","year":"2011","journal-title":"J Vet 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