{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T00:12:48Z","timestamp":1788567168041,"version":"build-2803163510"},"reference-count":38,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T00:00:00Z","timestamp":1770076800000},"content-version":"vor","delay-in-days":1190,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2022,9,15]],"date-time":"2022-09-15T00:00:00Z","timestamp":1663200000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>A 3-year-old female German Shepherd dog was presented with generalized tonic-clonic epileptic seizures, right-sided central vestibular syndrome, and right trigeminal nerve dysfunction. Acute lacunar ischemic strokes within both thalami, right side of the mesencephalon, left side of the myelencephalon, both sides of the cervical spinal cord, and acute hemorrhagic strokes within the rostral part of the right cerebellar hemisphere and right rostral colliculus were identified on magnetic resonance imaging. Additional evaluation identified multiple renal infarcts and complete splenic torsion, with entrapment of the left pancreatic lobe. Medical management, splenectomy, partial pancreatectomy, and intensive physical rehabilitation led to clinical improvement. The histology of the spleen was consistent with hemorrhagic infarction. Three months after onset, neurological examination identified only mild vestibular sequelae. The final diagnosis was multiple ischemic strokes secondary to primary splenic torsion. Spontaneous early hemorrhagic transformation, a well-known condition in human medicine, also was found in this case.<\/jats:p>","DOI":"10.1111\/jvim.16527","type":"journal-article","created":{"date-parts":[[2022,9,15]],"date-time":"2022-09-15T04:53:00Z","timestamp":1663217580000},"page":"2191-2198","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Suspected spontaneous early hemorrhagic transformation of multiple ischemic strokes secondary to primary splenic torsion in a German Shepherd dog"],"prefix":"10.1093","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0185-7738","authenticated-orcid":false,"given":"Nicolas","family":"Van Caenegem","sequence":"first","affiliation":[{"name":"U955-IMRB, Inserm, Ecole nationale v\u00e9t\u00e9rinaire d'Alfort, Unit\u00e9 de neurologie , Maisons-Alfort,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8844-2214","authenticated-orcid":false,"given":"Thibaut","family":"Troupel","sequence":"additional","affiliation":[{"name":"U955-IMRB, Inserm, Ecole nationale v\u00e9t\u00e9rinaire d'Alfort, Unit\u00e9 de neurologie , Maisons-Alfort,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4741-7685","authenticated-orcid":false,"given":"Jeremy","family":"Mortier","sequence":"additional","affiliation":[{"name":"Ecole nationale v\u00e9t\u00e9rinaire d'Alfort, Unit\u00e9 d'imagerie , Maisons-Alfort,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Laurent","family":"Thibaud","sequence":"additional","affiliation":[{"name":"MICEN Vet, Service de neurologie , 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