{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T16:44:15Z","timestamp":1789749855350,"version":"4.0.1"},"reference-count":20,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T00:00:00Z","timestamp":1770076800000},"content-version":"vor","delay-in-days":704,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2024,1,11]],"date-time":"2024-01-11T00:00:00Z","timestamp":1704931200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Gastrointestinal eosinophilic sclerosing fibroplasia (GESF) in cats presents as mass(es) associated with the gastrointestinal tract, mesentery, and abdominal lymph nodes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Hypothesis\/Objectives<\/jats:title>\n                    <jats:p>To report the clinicopathological findings, treatment, and outcome of cats with GESF.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Animals<\/jats:title>\n                    <jats:p>Sixty client-owned cats diagnosed with GESF.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Retrospective review of medical records of cats with histopathologically confirmed GESF.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The median age was 5.4\u2009years (interquartile range [IQR], 3.3-8.9.); 30% were Domestic Shorthairs and 12% were Domestic Longhair cats, with the most prevalent pedigree breeds being Ragdolls (25%), Exotic Shorthair (10%) and Persian (8%) cats. The median duration of clinical signs was 90\u2009days (IQR, 17.5-247.0); the most common clinical signs were weight loss (60%), hyporexia\/anorexia (55%), chronic vomiting (37%), lethargy (35%) and chronic diarrhea (27%). Masses were located in the small intestine (32%), stomach (27%), ileocolic junction (15%), colon (10%), lymph node (8%) and mesentery (8%) and 15% of cats had &amp;gt;1 mass. Eosinophilia was present in 50% and hypoalbuminemia in 28% of cats. The mass was removed surgically in 37% of cases. Most cats (98%) were treated with corticosteroids. Survival was not statistically different between cats treated with surgical resection and cats treated with medical therapy alone, 88% of the cats were still alive at the time of writing.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions and Clinical Importance<\/jats:title>\n                    <jats:p>GESF is an important differential diagnosis for abdominal masses in cats, and has a much better prognosis than previously reported.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jvim.16992","type":"journal-article","created":{"date-parts":[[2024,1,11]],"date-time":"2024-01-11T06:50:05Z","timestamp":1704955805000},"page":"1005-1012","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Clinicopathological findings, treatment, and outcome in 60 cats with gastrointestinal eosinophilic sclerosing fibroplasia"],"prefix":"10.1093","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4300-8534","authenticated-orcid":false,"given":"Petra","family":"\u010cern\u00e1","sequence":"first","affiliation":[{"name":"Colorado State University Department of Clinical Sciences, , Fort Collins, Colorado,","place":["USA"]},{"name":"Small Animal Clinic, The University of Veterinary Sciences Brno , Brno,","place":["Czech Republic"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristobal","family":"Lopez-Jimenez","sequence":"additional","affiliation":[{"name":"North Downs Specialist Referrals , Bletchingley,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenjiro","family":"Fukushima","sequence":"additional","affiliation":[{"name":"Veterinary Specialists & Emergency Center , Kawaguchi-shi, Saitama,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4823-4821","authenticated-orcid":false,"given":"Ko","family":"Nakashima","sequence":"additional","affiliation":[{"name":"Small Animal Medical Center , Saitama,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taisuke","family":"Nakagawa","sequence":"additional","affiliation":[{"name":"Veterinary Medical Centre, The University of Tokyo , Tokyo,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fiona","family":"Adam","sequence":"additional","affiliation":[{"name":"North Downs Specialist Referrals , Bletchingley,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Groth","sequence":"additional","affiliation":[{"name":"North Downs Specialist Referrals , Bletchingley,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Denning","sequence":"additional","affiliation":[{"name":"North Downs Specialist Referrals , Bletchingley,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8472-094X","authenticated-orcid":false,"given":"Nicolas","family":"Israeliantz","sequence":"additional","affiliation":[{"name":"The Royal (Dick) School of Veterinary Studies, University of Edinburgh , Midlothian,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dani\u00e8lle A.","family":"Gunn-Moore","sequence":"additional","affiliation":[{"name":"The Royal (Dick) School of Veterinary Studies, University of Edinburgh , Midlothian,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,3,1]]},"reference":[{"key":"2026020304071513300_jvim16992-bib-0001","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1354\/vp.46-1-63","article-title":"Feline gastrointestinal eosinophilic sclerosing fibroplasia","volume":"46","author":"Craig","year":"2009","journal-title":"Vet Pathol"},{"key":"2026020304071513300_jvim16992-bib-0002","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1177\/1098612X14568170","article-title":"Feline gastrointestinal eosinophilic sclerosing fibroplasia: 13 cases and review of an emerging clinical entity","volume":"17","author":"Linton","year":"2015","journal-title":"J Feline Med Surg"},{"key":"2026020304071513300_jvim16992-bib-0003","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1111\/jsap.12847","article-title":"A case of feline gastrointestinal eosinophilic sclerosing fibroplasia limited to the mesentery","volume":"61","author":"Kambe","year":"2020","journal-title":"J Small Anim Pract"},{"key":"2026020304071513300_jvim16992-bib-0004","article-title":"Diagnosis and management of a case of retroperitoneal eosinophilic sclerosing fibroplasia in a cat","volume":"5","author":"Thieme","year":"2019","journal-title":"J Feline Med Surg Open Rep"},{"key":"2026020304071513300_jvim16992-bib-0005","article-title":"Feline eosinophilic sclerosing fibroplasia\u2014a characteristic inflammatory response in sites beyond the gastrointestinal tract: case report and proposed nomenclature","volume":"8","author":"Zampieri","year":"2022","journal-title":"J Feline Med Surg Open Rep"},{"key":"2026020304071513300_jvim16992-bib-0006","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1080\/00480169.2014.933905","article-title":"A case of feline gastrointestinal eosinophilic sclerosing fibroplasia mimicking metastatic neoplasia","volume":"62","author":"Munday","year":"2014","journal-title":"N Z Vet J"},{"key":"2026020304071513300_jvim16992-bib-0007","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1111\/j.1476-5829.2010.00228_2.x","article-title":"Letters to the editor and rebuttal regarding the paper recently published in Veterinary and Comparative Oncology, \u2018Feline intestinal sclerosing mast cell tumour: 50 cases (1997-2008) 2010; 8: 72-79\u2019 by CHC Halsey, BE Powers and DA Kamstock. Letter to the editor# 2","volume":"8","author":"Gamble","year":"2010","journal-title":"Vet Comp Oncol"},{"key":"2026020304071513300_jvim16992-bib-0008","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1111\/j.1476-5829.2010.00228_1.x","article-title":"Letters to the editor and rebuttal regarding the paper recently published in Veterinary and Comparative Oncology, \u2018Feline intestinal sclerosing mast cell tumour: 50 cases (1997-2008) 2010; 8: 72-79\u2019 by C. H. C. Halsey, B. E. Powers and D. A. Kamstock. Letter to the editor #1","volume":"8","author":"Schulman","year":"2010","journal-title":"Vet Comp Oncol"},{"key":"2026020304071513300_jvim16992-bib-0009","first-page":"291","article-title":"Feline gastrointestinal eosinophilic sclerosing fibroplasia\u2014extracellular matrix proteins and TGF-\u03b21 immunoexpression","volume":"9","author":"Porras","year":"2022","journal-title":"Vet Sci"},{"key":"2026020304071513300_jvim16992-bib-0010","doi-asserted-by":"crossref","first-page":"481","DOI":"10.17555\/jvc.2017.12.34.6.481","article-title":"Feline gastrointestinal eosinophilic sclerosing fibroplasia in a Bengal cat","volume":"34","author":"Cho","year":"2017","journal-title":"J Vet Clin"},{"key":"2026020304071513300_jvim16992-bib-0011","doi-asserted-by":"crossref","first-page":"57","DOI":"10.24070\/bjvp.1983-0246.v15i1p57-61","article-title":"Feline gastrointestinal eosinophilic sclerosing fibroplasia","volume":"15","author":"Montenegro","year":"2022","journal-title":"Braz J Vet Pathol"},{"key":"2026020304071513300_jvim16992-bib-0012","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1293\/tox.26.51","article-title":"A case of feline gastrointestinal eosinophilic sclerosing fibroplasia","volume":"26","author":"Suzuki","year":"2013","journal-title":"J Toxicol Pathol"},{"key":"2026020304071513300_jvim16992-bib-0013","first-page":"309","article-title":"Remission of feline gastrointestinal eosinophilic sclerosing fibroplasia in a cat treated with corticotherapy","volume":"41","author":"Agulla","year":"2021","journal-title":"Pakistan Vet J"},{"key":"2026020304071513300_jvim16992-bib-0014","doi-asserted-by":"crossref","first-page":"773","DOI":"10.56808\/2985-1130.3178","article-title":"Successful management of feline gastrointestinal eosinophilic sclerosing fibroplasia with mycophenolate mofetil and prednisolone following surgical resection in a cat","volume":"51","author":"Kim","year":"2021","journal-title":"Thai J Vet Med"},{"key":"2026020304071513300_jvim16992-bib-0015","doi-asserted-by":"crossref","first-page":"81","DOI":"10.2327\/jjvas.46.81","article-title":"Surgical treatment of feline gastrointestinal eosinophilic sclerosing fibroplasia in a cat","volume":"46","author":"Takao","year":"2015","journal-title":"Jpn J Vet Anesth Surg"},{"key":"2026020304071513300_jvim16992-bib-0016","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1177\/1098612X12464224","article-title":"Ultrasonographic and clinicopathological features of feline gastrointestinal eosinophilic sclerosing fibroplasia in four cats","volume":"15","author":"Weissman","year":"2013","journal-title":"J Feline Med Surg"},{"key":"2026020304071513300_jvim16992-bib-0017","doi-asserted-by":"crossref","first-page":"295","DOI":"10.17221\/134\/2016-VETMED","article-title":"Recurrent feline gastrointestinal eosinophilic sclerosing fibroplasia and presumptive eosinophilic cystitis in a domestic short-haired cat: a case report","volume":"62","author":"Brloznik","year":"2017","journal-title":"Vet Med"},{"key":"2026020304071513300_jvim16992-bib-0018","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1354\/vp.40-3-283","article-title":"Abscess-forming inflammatory granulation tissue with Gram-positive cocci and prominent eosinophil infiltration in cats: possible infection of methicillin-resistant Staphylococcus","volume":"40","author":"Ozaki","year":"2003","journal-title":"Vet Pathol"},{"key":"2026020304071513300_jvim16992-bib-0019","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jfms.2005.04.003","article-title":"Prevalence of feline infectious peritonitis in specific cat breeds","volume":"8","author":"Pesteanu-Somogyi","year":"2006","journal-title":"J Feline Med Surg"},{"key":"2026020304071513300_jvim16992-bib-0020","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/j.jcpa.2014.08.005","article-title":"A case of feline gastrointestinal eosinophilic sclerosing fibroplasia associated with phycomycetes","volume":"151","author":"Grau-Roma","year":"2014","journal-title":"J Comp Pathol"}],"container-title":["Journal of Veterinary Internal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jvim\/article-pdf\/38\/2\/1005\/66665155\/jvim16992.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jvim\/article-pdf\/38\/2\/1005\/66665155\/jvim16992.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T09:07:26Z","timestamp":1770109646000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jvim\/article\/38\/2\/1005\/8448902"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,1]]},"references-count":20,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,3,1]]}},"URL":"https:\/\/doi.org\/10.1111\/jvim.16992","relation":{},"ISSN":["1939-1676"],"issn-type":[{"value":"1939-1676","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2024,3]]},"published":{"date-parts":[[2024,3,1]]},"assertion":[{"value":"2023-02-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-01-02","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-01-11","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}