{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T13:49:45Z","timestamp":1785419385514,"version":"3.56.0"},"reference-count":52,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T00:00:00Z","timestamp":1770076800000},"content-version":"vor","delay-in-days":643,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2024,4,15]],"date-time":"2024-04-15T00:00:00Z","timestamp":1713139200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Muscle atrophy and intramuscular fatty infiltration, as well as their association with prognosis, have not been quantified in dogs with spontaneous hypercortisolism (HC).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To quantitatively evaluate muscle atrophy and IM fatty infiltration in dogs with HC and determine their prognostic impact.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Animals<\/jats:title>\n                    <jats:p>Fifty-three dogs with HC and 66 control dogs without HC.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Retrospective cohort study. Medical records and computed tomography images obtained between 2014 and 2021 were evaluated. Kaplan-Meier curves and log-rank tests were used to analyze the effect of muscle atrophy and IM fatty infiltration on the prognosis of dogs with HC.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Dogs with HC showed lower visually measured cross-sectional area (VCSA) and cross-sectional area based on attenuation (HCSA) than control dogs (median [interquartile range {IQR}]: 50.3\u2009mm2\/mm [36.2-67.8] vs 66.7\u2009mm2\/mm [48.0-85.9]; P\u2009&amp;lt;\u2009.001; 30.4\u2009mm2\/mm [13.7-57.2] vs 54.8\u2009mm2\/mm [39.7-71.5]; P\u2009&amp;lt;\u2009.001, respectively). Dogs with HC had lower epaxial muscle attenuation (L3HU) than control dogs (median [IQR]: 21.2 Hounsfield [HU] [12.4-28.2] vs 33.2 HU [22.6-43.6]; P\u2009&amp;lt;\u2009.001). Dogs with HC with lower HCSA or L3HU had shorter survival (median [IQR]: 670\u2009days [222-673] vs 949\u2009days [788-1074], P\u2009&amp;lt;\u2009.01; 523\u2009days [132-670] vs 949\u2009days [756-1074], P\u2009&amp;lt;\u2009.01, respectively) but not lower VCSA (median [IQR]: 673\u2009days [132-788] vs 949\u2009days [523 to not applicable]; P\u2009=\u2009.30).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion and Clinical Importance<\/jats:title>\n                    <jats:p>Hypercortisolism in dogs causes muscle atrophy and IM fatty infiltration and is associated with poor prognosis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jvim.17065","type":"journal-article","created":{"date-parts":[[2024,4,16]],"date-time":"2024-04-16T00:23:54Z","timestamp":1713227034000},"page":"1334-1344","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Evaluation of muscle mass and intramuscular fatty infiltration in dogs with hypercortisolism and their association with prognosis"],"prefix":"10.1093","volume":"38","author":[{"given":"Kei","family":"Yoshida","sequence":"first","affiliation":[{"name":"The United Graduate School of Veterinary Science, Gifu University Joint Department of Veterinary Medicine, , Gifu,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yui","family":"Kobatake","sequence":"additional","affiliation":[{"name":"Faculty of Applied Biological Science, Gifu University Joint Department of Veterinary Medicine, , Gifu,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoshi","family":"Takashima","sequence":"additional","affiliation":[{"name":"Faculty of Applied Biological Science, Gifu University Joint Department of Veterinary Medicine, , Gifu,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2173-5420","authenticated-orcid":false,"given":"Naohito","family":"Nishii","sequence":"additional","affiliation":[{"name":"The United Graduate School of Veterinary Science, Gifu University Joint Department of Veterinary Medicine, , Gifu,","place":["Japan"]},{"name":"Faculty of Applied Biological Science, Gifu University Joint Department of Veterinary Medicine, , Gifu,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,5,1]]},"reference":[{"key":"2026020305120116900_jvim17065-bib-0001","first-page":"4345","article-title":"Textbook of Veterinary Internal Medicine. Diseases of the Dog and the Cat","author":"P\u00e9rez-Alenza","year":"2017","edition":"8th ed."},{"key":"2026020305120116900_jvim17065-bib-0002","doi-asserted-by":"crossref","DOI":"10.1210\/clinem\/dgz329","article-title":"Thigh muscle fat infiltration is associated with impaired physical performance despite remission in Cushing's syndrome","volume":"105","author":"Martel-Duguech","year":"2020","journal-title":"J Clin Endocrinol Metab"},{"key":"2026020305120116900_jvim17065-bib-0003","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1007\/s11102-022-01245-9","article-title":"Quality of life impairment after a diagnosis of Cushing's syndrome","volume":"25","author":"Webb","year":"2022","journal-title":"Pituitary"},{"key":"2026020305120116900_jvim17065-bib-0004","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1093\/gerona\/58.11.M1012","article-title":"Sarcopenia: effects on body composition and function","volume":"58","author":"Roubenoff","year":"2003","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"2026020305120116900_jvim17065-bib-0005","doi-asserted-by":"crossref","first-page":"2045","DOI":"10.1016\/j.clnu.2019.10.021","article-title":"Muscle mass, assessed at diagnosis by L3-CT scan as a prognostic marker of clinical outcomes in patients with gastric cancer: a systematic review and meta-analysis","volume":"39","author":"Rinninella","year":"2020","journal-title":"Clin Nutr"},{"key":"2026020305120116900_jvim17065-bib-0006","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1159\/000496460","article-title":"Low skeletal muscle mass independently predicts mortality in patients with chronic heart failure after an acute hospitalization","volume":"142","author":"Lopez","year":"2019","journal-title":"Cardiology"},{"key":"2026020305120116900_jvim17065-bib-0007","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejrad.2021.109943","article-title":"Methodology, clinical applications, and future directions of body composition analysis using computed tomography (CT) images: a review","volume":"145","author":"Tolonen","year":"2021","journal-title":"Eur J Radiol"},{"key":"2026020305120116900_jvim17065-bib-0008","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1007\/s40620-021-01167-y","article-title":"Low skeletal muscle mass by computerized tomography is associated with increased mortality risk in end-stage kidney disease patients on hemodialysis","volume":"35","author":"Sabatino","year":"2022","journal-title":"J Nephrol"},{"key":"2026020305120116900_jvim17065-bib-0009","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1530\/EJE-19-0464","article-title":"High mortality within 90\u2009days of diagnosis in patients with Cushing's syndrome: results from the ERCUSYN registry","volume":"181","author":"Valassi","year":"2019","journal-title":"Eur J Endocrinol"},{"key":"2026020305120116900_jvim17065-bib-0010","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/j.1939-1676.1991.tb00922.x","article-title":"Canine hyperadrenocorticism due to adrenocortical neoplasia: pretreatment evaluation of 41 dogs","volume":"5","author":"Reusch","year":"1991","journal-title":"J Vet Intern Med"},{"key":"2026020305120116900_jvim17065-bib-0011","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1590\/1678-5150-pvb-6105","article-title":"Epidemiological, clinical, and laboratory aspects in a case series of canine hyperadrenocorticism: 115 cases (2010-2014)","volume":"39","author":"Martins","year":"2019","journal-title":"Pesqui Vet Bras"},{"key":"2026020305120116900_jvim17065-bib-0012","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1016\/S0195-5616(84)50078-3","article-title":"Hyperadrenocorticism","volume":"14","author":"Peterson","year":"1984","journal-title":"Vet Clin North Am Small Anim Pract"},{"key":"2026020305120116900_jvim17065-bib-0013","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1111\/jvim.12303","article-title":"Long-term survival of dogs with adrenal-dependent hyperadrenocorticism: a comparison between mitotane and twice daily trilostane treatment","volume":"28","author":"Arenas","year":"2014","journal-title":"J Vet Intern Med"},{"key":"2026020305120116900_jvim17065-bib-0014","doi-asserted-by":"crossref","DOI":"10.1002\/vetr.1630","article-title":"Survival of dogs with pituitary-dependent hyperadrenocorticism treated twice daily with low doses of trilostane","volume":"191","author":"Garc\u00eda San Jos\u00e9","year":"2022","journal-title":"Vet Rec"},{"key":"2026020305120116900_jvim17065-bib-0015","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/s12917-018-1768-6","article-title":"Abdominal volume computed tomography assessment of body composition in dogs","volume":"15","author":"Turner","year":"2019","journal-title":"BMC Vet Res"},{"key":"2026020305120116900_jvim17065-bib-0016","first-page":"255","article-title":"Quantitative assessment of muscle in dogs using a vertebral epaxial muscle score","volume":"81","author":"Freeman","year":"2017","journal-title":"Can J Vet Res"},{"key":"2026020305120116900_jvim17065-bib-0017","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1677\/JOE-07-0606","article-title":"Mechanisms of glucocorticoid-induced myopathy","volume":"197","author":"Schakman","year":"2008","journal-title":"J Endocrinol"},{"key":"2026020305120116900_jvim17065-bib-0018","doi-asserted-by":"crossref","first-page":"788","DOI":"10.3389\/fphys.2017.00788","article-title":"mTOR as a key regulator in maintaining skeletal muscle mass","volume":"8","author":"Yoon","year":"2017","journal-title":"Front Physiol"},{"key":"2026020305120116900_jvim17065-bib-0019","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1093\/ageing\/afy169","article-title":"Sarcopenia: revised European consensus on definition and diagnosis","volume":"48","author":"Cruz-Jentoft","year":"2019","journal-title":"Age Ageing"},{"key":"2026020305120116900_jvim17065-bib-0020","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.rvsc.2022.03.011","article-title":"Epaxial muscle atrophy is more evident in large dogs with intervertebral disc disease than in dogs with ischaemic myelopathy","volume":"146","author":"Bostr\u00f6m","year":"2022","journal-title":"Res Vet Sci"},{"key":"2026020305120116900_jvim17065-bib-0021","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1292\/jvms.21-0325","article-title":"Quantitative assessment of muscle mass and gene expression analysis in dogs with glucocorticoid-induced muscle atrophy","volume":"84","author":"Yoshida","year":"2022","journal-title":"J Vet Med Sci"},{"key":"2026020305120116900_jvim17065-bib-0022","doi-asserted-by":"crossref","first-page":"2163","DOI":"10.1016\/j.biocel.2013.05.036","article-title":"Glucocorticoid-induced skeletal muscle atrophy","volume":"45","author":"Schakman","year":"2013","journal-title":"Int J Biochem Cell Biol"},{"key":"2026020305120116900_jvim17065-bib-0023","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1093\/gerona\/gls168","article-title":"Variations of CT-based trunk muscle attenuation by age, sex, and specific muscle","volume":"68","author":"Anderson","year":"2013","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"2026020305120116900_jvim17065-bib-0024","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1111\/j.1749-6632.2000.tb06416.x","article-title":"Composition of skeletal muscle evaluated with computed tomography","volume":"904","author":"Goodpaster","year":"2000","journal-title":"Ann N Y Acad Sci"},{"key":"2026020305120116900_jvim17065-bib-0025","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1152\/jappl.2000.89.1.104","article-title":"Skeletal muscle attenuation determined by computed tomography is associated with skeletal muscle lipid content","volume":"89","author":"Goodpaster","year":"2000","journal-title":"J Appl Physiol"},{"key":"2026020305120116900_jvim17065-bib-0026","doi-asserted-by":"crossref","first-page":"174","DOI":"10.2460\/ajvr.80.2.174","article-title":"Comparison of computed tomographic attenuation values for epaxial muscles in old and young dogs","volume":"80","author":"Sutherland-Smith","year":"2019","journal-title":"Am J Vet Res"},{"key":"2026020305120116900_jvim17065-bib-0027","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1111\/vru.12114","article-title":"Comparison between noncontrast computed tomography and magnetic resonance imaging for detection and characterization of thoracolumbar myelopathy caused by intervertebral disk herniation in dogs","volume":"55","author":"Cooper","year":"2014","journal-title":"Vet Radiol Ultrasound"},{"key":"2026020305120116900_jvim17065-bib-0028","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0054553","article-title":"Muscle side population cells from dystrophic or injured muscle adopt a fibro-adipogenic fate","volume":"8","author":"Penton","year":"2013","journal-title":"PLoS One"},{"key":"2026020305120116900_jvim17065-bib-0029","doi-asserted-by":"crossref","first-page":"69","DOI":"10.3389\/fendo.2016.00069","article-title":"Fatty infiltration of skeletal muscle: mechanisms and comparisons with bone marrow adiposity","volume":"7","author":"Hamrick","year":"2016","journal-title":"Front Endocrinol"},{"key":"2026020305120116900_jvim17065-bib-0030","doi-asserted-by":"crossref","first-page":"2161","DOI":"10.1177\/0363546518769267","article-title":"Fatty infiltration is a prognostic marker of muscle function after rotator cuff tear","volume":"46","author":"Valencia","year":"2018","journal-title":"Am J Sports Med"},{"key":"2026020305120116900_jvim17065-bib-0031","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.yexcr.2014.03.021","article-title":"Myotube formation is affected by adipogenic lineage cells in a cell-to-cell contact-independent manner","volume":"324","author":"Takegahara","year":"2014","journal-title":"Exp Cell Res"},{"key":"2026020305120116900_jvim17065-bib-0032","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1530\/EJE-16-0689","article-title":"Persistence of myopathy in Cushing's syndrome: evaluation of the German Cushing's registry","volume":"176","author":"Berr","year":"2017","journal-title":"Eur J Endocrinol"},{"key":"2026020305120116900_jvim17065-bib-0033","first-page":"1207","article-title":"Prognostic value of paravertebral muscle density in patients with spinal metastases from gastrointestinal cancer","volume":"27","author":"Dohzono","year":"2019","journal-title":"Support Care Cancer"},{"key":"2026020305120116900_jvim17065-bib-0034","doi-asserted-by":"crossref","first-page":"254","DOI":"10.2460\/ajvr.81.3.254","article-title":"Usefulness of muscle condition score and ultrasonographic measurements for assessment of muscle mass in cats with cachexia and sarcopenia","volume":"81","author":"Freeman","year":"2020","journal-title":"Am J Vet Res"},{"key":"2026020305120116900_jvim17065-bib-0035","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1002\/aja.1001630107","article-title":"Distribution of fiber types in locomotory muscles of dogs","volume":"163","author":"Armstrong","year":"1982","journal-title":"Am J Anat"},{"key":"2026020305120116900_jvim17065-bib-0036","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.1152\/physrev.00031.2010","article-title":"Fiber types in mammalian skeletal muscles","volume":"91","author":"Schiaffino","year":"2011","journal-title":"Physiol Rev"},{"key":"2026020305120116900_jvim17065-bib-0037","first-page":"243","article-title":"Mechanisms for fiber-type specificity of skeletal muscle atrophy","volume":"16","author":"Wang","year":"2013","journal-title":"Curr Opin Clin Nutr Metab Care"},{"key":"2026020305120116900_jvim17065-bib-0038","doi-asserted-by":"crossref","first-page":"1794","DOI":"10.2460\/ajvr.73.11.1794","article-title":"Assessment of methods of evaluating sarcopenia in old dogs","volume":"73","author":"Hutchinson","year":"2012","journal-title":"Am J Vet Res"},{"key":"2026020305120116900_jvim17065-bib-0039","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.cmet.2014.12.021","article-title":"Muscle as a \u2018mediator\u2019 of systemic metabolism","volume":"21","author":"Baskin","year":"2015","journal-title":"Cell Metab"},{"key":"2026020305120116900_jvim17065-bib-0040","doi-asserted-by":"crossref","first-page":"3033","DOI":"10.3390\/jcm10143033","article-title":"The prognostic value of low muscle mass in pancreatic cancer patients: a systematic review and meta-analysis","volume":"10","author":"Pierobon","year":"2021","journal-title":"J Clin Med"},{"key":"2026020305120116900_jvim17065-bib-0041","doi-asserted-by":"crossref","first-page":"2133","DOI":"10.1152\/physrev.00063.2017","article-title":"Mechanisms of insulin action and insulin resistance","volume":"98","author":"Petersen","year":"2018","journal-title":"Physiol Rev"},{"key":"2026020305120116900_jvim17065-bib-0042","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/j.physbeh.2007.12.002","article-title":"Muscular diacylglycerol metabolism and insulin resistance","volume":"94","author":"Timmers","year":"2008","journal-title":"Physiol Behav"},{"key":"2026020305120116900_jvim17065-bib-0043","doi-asserted-by":"crossref","first-page":"R561","DOI":"10.1152\/ajpregu.00198.2015","article-title":"Diminished anabolic signaling response to insulin induced by intramuscular lipid accumulation is associated with inflammation in aging but not obesity","volume":"310","author":"Rivas","year":"2016","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"2026020305120116900_jvim17065-bib-0044","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1359\/jbmr.090807","article-title":"Computed tomographic measurements of thigh muscle cross-sectional area and attenuation coefficient predict hip fracture: the health, aging, and body composition study","volume":"25","author":"Lang","year":"2010","journal-title":"J Bone Miner Res"},{"key":"2026020305120116900_jvim17065-bib-0045","doi-asserted-by":"crossref","first-page":"767.e1","DOI":"10.1016\/j.jamda.2016.05.016","article-title":"Recent advances in sarcopenia research in Asia: 2016 update from the Asian working group for sarcopenia","volume":"17","author":"Chen","year":"2016","journal-title":"J Am Med Dir Assoc"},{"key":"2026020305120116900_jvim17065-bib-0046","doi-asserted-by":"crossref","first-page":"913","DOI":"10.4103\/2230-8210.117215","article-title":"Glucocorticoid-induced myopathy: pathophysiology, diagnosis, and treatment","volume":"17","author":"Gupta","year":"2013","journal-title":"Indian J Endocrinol Metab"},{"key":"2026020305120116900_jvim17065-bib-0047","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1016\/S0733-8619(05)70339-X","article-title":"Endocrine neuromyopathies","volume":"15","author":"Anagnos","year":"1997","journal-title":"Neurol Clin"},{"key":"2026020305120116900_jvim17065-bib-0048","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1136\/vr.102546","article-title":"Prognostic factors for survival in dogs with pituitary-dependent hypercortisolism treated with trilostane","volume":"176","author":"Fracassi","year":"2015","journal-title":"Vet Rec"},{"key":"2026020305120116900_jvim17065-bib-0049","doi-asserted-by":"crossref","first-page":"1292","DOI":"10.1111\/jvim.12192","article-title":"Diagnosis of spontaneous canine hyperadrenocorticism: 2012 ACVIM consensus statement (small animal)","volume":"27","author":"Behrend","year":"2013","journal-title":"J Vet Intern Med"},{"key":"2026020305120116900_jvim17065-bib-0050","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1111\/jsap.12904","article-title":"Canine hyperadrenocorticism associations with signalment, selected comorbidities and mortality within North American veterinary teaching hospitals","volume":"59","author":"Hoffman","year":"2018","journal-title":"J Small Anim Pract"},{"key":"2026020305120116900_jvim17065-bib-0051","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1136\/vr.105159","article-title":"Survival analysis of 219 dogs with hyperadrenocorticism attending primary care practice in England","volume":"186","author":"Schofield","year":"2020","journal-title":"Vet Rec"},{"key":"2026020305120116900_jvim17065-bib-0052","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1136\/vr.150.26.799","article-title":"Trilostane treatment of 78 dogs with pituitary-dependent hyperadrenocorticism","volume":"150","author":"Neiger","year":"2002","journal-title":"Vet Rec"}],"container-title":["Journal of Veterinary Internal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jvim\/article-pdf\/38\/3\/1334\/66720901\/jvim17065.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jvim\/article-pdf\/38\/3\/1334\/66720901\/jvim17065.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T10:12:13Z","timestamp":1770113533000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jvim\/article\/38\/3\/1334\/8456017"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,1]]},"references-count":52,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,5,1]]}},"URL":"https:\/\/doi.org\/10.1111\/jvim.17065","relation":{},"ISSN":["1939-1676"],"issn-type":[{"value":"1939-1676","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2024,5]]},"published":{"date-parts":[[2024,5,1]]},"assertion":[{"value":"2023-08-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-03-22","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-15","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}