{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T21:50:58Z","timestamp":1770155458472,"version":"3.49.0"},"reference-count":12,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T00:00:00Z","timestamp":1770076800000},"content-version":"vor","delay-in-days":582,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2024,5,4]],"date-time":"2024-05-04T00:00:00Z","timestamp":1714780800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>An 11-year-old female spayed German Wirehaired Pointer with a 1-week history of lethargy, hyporexia, diarrhea, and coughing presented with pericardial effusion causing cardiac tamponade. An echocardiogram revealed no structural cause for pericardial effusion. The pericardial effusion was an exudate with mixed macrophagic and neutrophilic inflammation. Morulae occasionally were found within neutrophils. The pericardial fluid and blood were qPCR and cPCR positive for Anaplasma phagocytophilum (NC State University, Vector-borne Disease Diagnostic Laboratory, Raleigh, NC). The dog's blood was negative by ELISA (Vetscan Flex4 Rapid Test, Zoetis, Parsippany, NJ) for A. phagocytophilum antibodies at initial presentation and subsequently positive (SNAP4DxPlus, IDEXX, Westbrook, ME) 7\u2009days later. After pericardiocentesis and administration of doxycycline (5\u2009mg\/kg PO q12h for 14\u2009days), a repeat echocardiogram performed 1\u2009month later showed no recurrence of pericardial effusion.<\/jats:p>","DOI":"10.1111\/jvim.17090","type":"journal-article","created":{"date-parts":[[2024,5,4]],"date-time":"2024-05-04T10:34:37Z","timestamp":1714818877000},"page":"2339-2343","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Detection of\n                    <i>Anaplasma phagocytophilum<\/i>\n                    in an inflammatory pericardial effusion of a dog"],"prefix":"10.1093","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-6300-0230","authenticated-orcid":false,"given":"Betsy K.","family":"Murdock","sequence":"first","affiliation":[{"name":"University of Wisconsin-Madison School of Veterinary Medicine, Department of Pathobiological Sciences, , Madison, Wisconsin,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan F.","family":"Bach","sequence":"additional","affiliation":[{"name":"University of Wisconsin-Madison School of Veterinary Medicine, Department of Medical Sciences, , Madison, Wisconsin,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9849-2511","authenticated-orcid":false,"given":"Barbara A.","family":"Qurollo","sequence":"additional","affiliation":[{"name":"North Carolina State University College of Veterinary Medicine, Department of Clinical Sciences, , Raleigh, North Carolina,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0949-5698","authenticated-orcid":false,"given":"Erin W.","family":"Lashnits","sequence":"additional","affiliation":[{"name":"University of Wisconsin-Madison School of Veterinary Medicine, Department of Medical Sciences, , Madison, Wisconsin,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristen R.","family":"Friedrichs","sequence":"additional","affiliation":[{"name":"University of Wisconsin-Madison School of Veterinary Medicine, Department of Pathobiological Sciences, , Madison, Wisconsin,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,7,1]]},"reference":[{"key":"2026020304093261600_jvim17090-bib-0001","first-page":"8","article-title":"Epidemiological and clinicopathological features of Anaplasma phagocytophilum infection in dogs: a systematic review","volume":"8","author":"El Hamiani","year":"2021","journal-title":"Front Vet Sci."},{"issue":"4","key":"2026020304093261600_jvim17090-bib-0002","doi-asserted-by":"crossref","first-page":"276","DOI":"10.5326\/JAAHA-MS-5652","article-title":"An unusual presentation of granulocytic anaplasmosis in a young 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diagnosis of anaplasmosis and ehrlichiosis in dogs","volume":"82","author":"Qurollo","year":"2021","journal-title":"Am J Vet Res."},{"issue":"4","key":"2026020304093261600_jvim17090-bib-0012","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1111\/j.1939-1676.2012.00968.x","article-title":"Ehrlichia muris infection in a dog from Minnesota","volume":"26","author":"Hegarty","year":"2012","journal-title":"J Vet Intern Med."}],"container-title":["Journal of Veterinary Internal 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