{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T09:32:19Z","timestamp":1777627939924,"version":"3.51.4"},"reference-count":27,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T00:00:00Z","timestamp":1770076800000},"content-version":"vor","delay-in-days":582,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2024,4,25]],"date-time":"2024-04-25T00:00:00Z","timestamp":1714003200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Granuloprival degeneration is an uncommon form of cerebellar cortical degeneration (CCD). A 3-month-old Yorkshire Terrier and a 7-month-old Lagotto Romagnolo dog were presented with a history of progressive cerebellar dysfunction including wide-based stance, cerebellar ataxia, intention tremors, and loss of menace response despite normal vision. Magnetic resonance imaging of the brain identified marked diffuse decrease of the cerebellum size. Euthanasia was performed in both cases because of progression of clinical signs. Histopathological examination identified marked diffuse thinning of the granular cell layer with almost complete loss of the granular cell neurons, providing a definitive diagnosis of granuloprival CCD. Granuloprival CCD should be considered as a differential diagnosis in Yorkshire Terrier and Lagotto Romagnolo dogs with post-natal progressive clinical signs of cerebellar dysfunction.<\/jats:p>","DOI":"10.1111\/jvim.17091","type":"journal-article","created":{"date-parts":[[2024,4,25]],"date-time":"2024-04-25T13:19:30Z","timestamp":1714051170000},"page":"2368-2372","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Granuloprival cerebellar cortical degeneration in a Yorkshire Terrier and Lagotto Romagnolo dog"],"prefix":"10.1093","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7463-7069","authenticated-orcid":false,"given":"Thomas","family":"Mignan","sequence":"first","affiliation":[{"name":"Dovecote Veterinary Hospital, 5 Delven Lane, Castle Donington , Derby DE74 2LJ,","place":["United Kingdom"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mart\u00ed","family":"Pumarola","sequence":"additional","affiliation":[{"name":"Veterinary Faculty, Universitat Aut\u00f2noma de Barcelona, Bellaterra (Cerdanyola del Vall\u00e8s) Department of Animal Medicine and Surgery, , Barcelona 08193,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon","family":"Platt","sequence":"additional","affiliation":[{"name":"CVS Teleneurology, 1 Owen Road , Diss IP22 4ER,","place":["United Kingdom"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew","family":"James","sequence":"additional","affiliation":[{"name":"Dovecote Veterinary Hospital, 5 Delven Lane, Castle Donington , Derby DE74 2LJ,","place":["United Kingdom"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta","family":"Pereira","sequence":"additional","affiliation":[{"name":"School of Veterinary Medicine and Science, University of Nottingham , Sutton Bonington, Leicestershire LE12 5RD,","place":["United Kingdom"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonia","family":"Morey-Matamalas","sequence":"additional","affiliation":[{"name":"School of Veterinary Medicine and Science, University of Nottingham , Sutton Bonington, Leicestershire LE12 5RD,","place":["United Kingdom"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alfredo","family":"Recio","sequence":"additional","affiliation":[{"name":"Cl\u00ednica Veterinaria Levante, Avenida de La Uni\u00f3n 61 , San Javier, Murcia 30730,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,7,1]]},"reference":[{"issue":"4","key":"2026020304093036500_jvim17091-bib-0001","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1016\/j.cvsm.2014.07.005","article-title":"Canine hereditary ataxia","volume":"44","author":"Urkasemsin","year":"2014","journal-title":"Vet Clin North Am. 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