{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T21:38:37Z","timestamp":1770154717053,"version":"3.49.0"},"reference-count":22,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T00:00:00Z","timestamp":1770076800000},"content-version":"vor","delay-in-days":459,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2024,10,17]],"date-time":"2024-10-17T00:00:00Z","timestamp":1729123200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The relationship between collapse and a diagnosis of hypoadrenocorticism is not well understood in dogs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Hypothesis<\/jats:title>\n                    <jats:p>To assess the prevalence of episodes of collapse in dogs screened for hypoadrenocorticism, and to assess the prevalence of confirmed hypoadrenocorticism in dogs presenting with reported collapse.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Animals<\/jats:title>\n                    <jats:p>Seventy-three client-owned dogs with resting cortisol concentrations were measured and presented to a University teaching hospital for collapse.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Retrospective review of medical records of dogs at a single center.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The prevalence of episodes of collapse in dogs that had a resting cortisol measurement was 73\/856 (8.5%; 95% confidence interval [95% CI], 6.7%-10.6%). Resting cortisol concentration was &amp;lt;2\u2009\u03bcg\/dL (&amp;lt;55\u2009nmol\/L) in 19 dogs. Cortisol concentration after ACTH stimulation was &amp;lt;2\u2009\u03bcg\/dL (&amp;lt;55\u2009nmol\/L) in 1 of the 73 dogs in this cohort, consistent with a diagnosis of hypoadrenocorticism, giving a prevalence estimate of hypoadrenocorticism of 1.3% (95% CI, 0.15%-6.2%). In 8 dogs with an initial resting cortisol concentration &amp;lt;2\u2009\u03bcg\/dL (&amp;lt;55\u2009nmol\/L), hypoadrenocorticism was excluded based on a repeat resting cortisol concentration &amp;gt;2\u2009\u03bcg\/dL (&amp;gt;55\u2009nmol\/L). The most common diagnosis was vasovagal syncope (10\/73), followed by sick sinus syndrome and third-degree atrioventricular block (2\/73). The final diagnosis was unknown in 24\/73 dogs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions and Clinical Importance<\/jats:title>\n                    <jats:p>Hypoadrenocorticism was the final diagnosis in 1 of 73 dogs presented to a teaching hospital either in a collapsed state or with a previous history of episodes of collapse. No dog presenting as cardiovascularly stable for intermittent collapse was found to have hypoadrenocorticism.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jvim.17214","type":"journal-article","created":{"date-parts":[[2024,10,17]],"date-time":"2024-10-17T11:00:39Z","timestamp":1729162839000},"page":"3025-3030","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Resting cortisol concentrations in dogs presenting to a university teaching hospital with collapse"],"prefix":"10.1093","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8290-7559","authenticated-orcid":false,"given":"Ana","family":"Fernandez Gallego","sequence":"first","affiliation":[{"name":"The Royal (Dick) School of Veterinary Studies and the Roslin Institute, Easter Bush Campus, The University of Edinburgh , Midlothian,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6933-723X","authenticated-orcid":false,"given":"Craig Robert","family":"Breheny","sequence":"additional","affiliation":[{"name":"The Royal (Dick) School of Veterinary Studies and the Roslin Institute, Easter Bush Campus, The University of Edinburgh , Midlothian,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4297-8870","authenticated-orcid":false,"given":"Adam G.","family":"Gow","sequence":"additional","affiliation":[{"name":"The Royal (Dick) School of Veterinary Studies and the Roslin Institute, Easter Bush Campus, The University of Edinburgh , Midlothian,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3819-1821","authenticated-orcid":false,"given":"Alisdair M.","family":"Boag","sequence":"additional","affiliation":[{"name":"The Royal (Dick) School of Veterinary Studies and the Roslin Institute, Easter Bush Campus, The University of Edinburgh , Midlothian,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,11,1]]},"reference":[{"key":"2026020304133403000_jvim17214-bib-0001","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1136\/inpract.27.1.16","article-title":"Differential diagnosis of collapse in the dog. 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