{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T22:29:06Z","timestamp":1781562546665,"version":"3.54.5"},"reference-count":26,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T00:00:00Z","timestamp":1770076800000},"content-version":"vor","delay-in-days":278,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,3,28]],"date-time":"2025-03-28T00:00:00Z","timestamp":1743120000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Fungal rhinosinusitis in cats is an uncommon condition with sparse literature regarding the presentation, causative agents, diagnosis, treatment, and prognosis within the UK.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Hypothesis\/Objectives<\/jats:title>\n                    <jats:p>To describe and report the presenting clinical signs, diagnostic imaging findings, treatment approach, and outcome of cats diagnosed with fungal rhinosinusitis in the UK.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Animals<\/jats:title>\n                    <jats:p>Thirty-four client-owned cats were diagnosed with fungal rhinosinusitis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Retrospective multicenter observational study. Cases presenting at 10 UK referral centers between January 2013 and December 2022 were retrospectively recruited.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Median duration of clinical signs was 3\u2009months (0.5-42-months). The most common signs were sneezing (27\/34, 79%) and nasal discharge (21\/34, 62%). Turbinate lysis was present in 27\/34 cases (79%) and always involved the caudal nasal cavity. Osteolysis of the frontal bone, orbit, or cribriform plate was observed in 16\/34 cases (47%). At least two tests from fungal culture, panfungal PCR, and histopathology were performed in all cases, and in 8\/34 cases (24%) only one was positive. The treatment approach varied, with debridement, topical clotrimazole, and systemic azole therapy used alone or in various combinations, and repeat treatment occurred in 9\/34 cases (26%). Clinical remission &amp;gt;\u200990\u2009days after treatment was found in 9\/24 cases (38%), but case fatality rates were low, with 3\/34 cases (9%) dying with clinical disease during available follow-up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions and Clinical Importance<\/jats:title>\n                    <jats:p>Fungal rhinosinusitis should be considered in cats of any age with clinical signs of nasal disease. The prognosis from this data appears guarded for cats with fungal rhinosinusitis, with less than 50% of cats achieving long-term clinical remission.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jvim.70076","type":"journal-article","created":{"date-parts":[[2025,3,30]],"date-time":"2025-03-30T19:35:14Z","timestamp":1743363314000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Fungal Rhinosinusitis in Cats in the United Kingdom: 34\u00a0Cases (2013\u20132022)"],"prefix":"10.1093","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-0205-4678","authenticated-orcid":false,"given":"Oliver Luke","family":"Russell","sequence":"first","affiliation":[{"name":"Queen's Veterinary School Hospital, University of Cambridge , Cambridge,","place":["UK"]},{"name":"Vets Now Hospital Manchester , 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