{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T02:42:06Z","timestamp":1790044926794,"version":"4.0.1"},"reference-count":48,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2014,9,18]],"date-time":"2014-09-18T00:00:00Z","timestamp":1410998400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2014,9,18]],"date-time":"2014-09-18T00:00:00Z","timestamp":1410998400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Project G35\/10-A"},{"name":"PICATA predoctoral fellowship of the Moncloa Campus of International Excellence"},{"name":"FPU predoctoral fellowship by the Spanish Ministry of Education, Culture and Sport"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Lett Appl Microbiol"],"published-print":{"date-parts":[[2014,12]]},"DOI":"10.1111\/lam.12314","type":"journal-article","created":{"date-parts":[[2014,8,7]],"date-time":"2014-08-07T08:29:31Z","timestamp":1407400171000},"page":"594-603","source":"Crossref","is-referenced-by-count":23,"title":["A simple mathematical model that describes the growth of the area and the number of total and viable cells in yeast colonies"],"prefix":"10.1093","volume":"59","author":[{"given":"E.-M.","family":"Rivas","sequence":"first","affiliation":[{"name":"CEI Campus Moncloa; UCM-UPM; Madrid Spain"},{"name":"Departamento de Microbiolog\u00eda III; Facultad de Biolog\u00eda; Universidad Complutense de Madrid; Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Gil de Prado","sequence":"additional","affiliation":[{"name":"CEI Campus Moncloa; UCM-UPM; Madrid Spain"},{"name":"Departamento de Microbiolog\u00eda III; Facultad de Biolog\u00eda; Universidad Complutense de Madrid; Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Wrent","sequence":"additional","affiliation":[{"name":"CEI Campus Moncloa; UCM-UPM; Madrid Spain"},{"name":"Departamento de Microbiolog\u00eda III; Facultad de Biolog\u00eda; Universidad Complutense de Madrid; Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.-I.","family":"de Sil\u00f3niz","sequence":"additional","affiliation":[{"name":"CEI Campus Moncloa; UCM-UPM; Madrid Spain"},{"name":"Departamento de Microbiolog\u00eda III; Facultad de Biolog\u00eda; Universidad Complutense de Madrid; Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Barreiro","sequence":"additional","affiliation":[{"name":"CEI Campus Moncloa; UCM-UPM; Madrid Spain"},{"name":"LPF_TAGRALIA; Departamento de Ingenier\u00eda Rural; ETSI Agr\u00f3nomos; Universidad Polit\u00e9cnica de Madrid; Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.C.","family":"Correa","sequence":"additional","affiliation":[{"name":"CEI Campus Moncloa; UCM-UPM; Madrid Spain"},{"name":"LPF_TAGRALIA; Departamento de Ingenier\u00eda Rural; ETSI Agr\u00f3nomos; Universidad Polit\u00e9cnica de Madrid; Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Conejero","sequence":"additional","affiliation":[{"name":"Departamento de Matem\u00e1tica Aplicada (Biomatem\u00e1tica); Facultad de Biolog\u00eda; Universidad Complutense de Madrid; Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Murciano","sequence":"additional","affiliation":[{"name":"Departamento de Matem\u00e1tica Aplicada (Biomatem\u00e1tica); Facultad de Biolog\u00eda; Universidad Complutense de Madrid; Madrid Spain"},{"name":"Grupo de Neurorob\u00f3tica y Neurocomputaci\u00f3n; Universidad Complutense de Madrid; Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.M.","family":"Peinado","sequence":"additional","affiliation":[{"name":"CEI Campus Moncloa; UCM-UPM; Madrid Spain"},{"name":"Departamento de Microbiolog\u00eda III; Facultad de Biolog\u00eda; Universidad Complutense de Madrid; Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2014,9,18]]},"reference":[{"key":"10.1111\/lam.12314-BIB0001|lam12314-cit-0001","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1083\/jcb.200604072","article-title":"Isolation of quiescent and nonquiescent cells from yeast stationary-phase cultures","volume":"174","author":"Allen","year":"2006","journal-title":"J Cell Biol"},{"key":"10.1111\/lam.12314-BIB0002|lam12314-cit-0002","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/0168-1605(94)90157-0","article-title":"A dynamic approach to predicting bacterial growth in food","volume":"23","author":"Baranyi","year":"1994","journal-title":"Food Microbiol"},{"key":"10.1111\/lam.12314-BIB0003|lam12314-cit-0003","doi-asserted-by":"crossref","first-page":"5607","DOI":"10.1128\/AEM.00429-09","article-title":"Quantitative physiology of Saccharomyces cerevisiae at near-zero specific growth rates","volume":"75","author":"Boender","year":"2009","journal-title":"Appl Environ Microbiol"},{"key":"10.1111\/lam.12314-BIB0004|lam12314-cit-0004","volume-title":"Distribution-Free Statistical Tests","author":"Bradley","year":"1968"},{"key":"10.1111\/lam.12314-BIB0005|lam12314-cit-0005","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1038\/cdd.2009.219","article-title":"Apoptosis in yeast: triggers, pathways, subroutines","volume":"17","author":"Carmona-Gutierrez","year":"2010","journal-title":"Cell Death Differ"},{"key":"10.1111\/lam.12314-BIB0006|lam12314-cit-0006","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1098\/rspb.1968.0063","article-title":"Factors affecting the growth of bacterial colonies on agar plates","volume":"171","author":"Cooper","year":"1968","journal-title":"Proc R Soc Lond B Biol Sci"},{"key":"10.1111\/lam.12314-BIB0007|lam12314-cit-0007","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1046\/j.1472-765X.2003.01340.x","article-title":"Modelling the individual cell lag phase. Isolating single cells: protocol development","volume":"37","author":"Francois","year":"2003","journal-title":"Lett Appl Microbiol"},{"key":"10.1111\/lam.12314-BIB0008|lam12314-cit-0008","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/0301-4622(74)80006-2","article-title":"Growth rates of yeast colonies on solid media","volume":"1","author":"Gray","year":"1974","journal-title":"Biophys Chem"},{"key":"10.1111\/lam.12314-BIB0009|lam12314-cit-0009","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/j.mimet.2005.08.007","article-title":"Automated image analysis of bacterial colony growth as a tool to study individual lag time distributions of immobilized cells","volume":"65","author":"Guillier","year":"2006","journal-title":"J Microbiol Methods"},{"key":"10.1111\/lam.12314-BIB0010|lam12314-cit-0010","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1046\/j.1365-2672.2000.00848.x","article-title":"Growth of Listeria monocytogenes and Yersinia enterocolitica colonies under modified atmospheres at 4 and 8\u00b0C using a model food system","volume":"88","author":"Harrison","year":"2000","journal-title":"J Appl Microbiol"},{"key":"10.1111\/lam.12314-BIB0011|lam12314-cit-0011","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1083\/jcb.200310014","article-title":"Chronological aging leads to apoptosis in yeast","volume":"164","author":"Herker","year":"2004","journal-title":"J Cell Biol"},{"key":"10.1111\/lam.12314-BIB0012|lam12314-cit-0012","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/S0168-1605(00)00520-1","article-title":"Microstructural factors controlling the survival of food-borne pathogens in porous media","volume":"66","author":"Hills","year":"2001","journal-title":"Int J Food Microbiol"},{"key":"10.1111\/lam.12314-BIB0013|lam12314-cit-0013","first-page":"3061","article-title":"Growth of yeast colonies on solid media","volume":"134","author":"Kamath","year":"1988","journal-title":"J Gen Microbiol"},{"key":"10.1111\/lam.12314-BIB0014|lam12314-cit-0014","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/j.fm.2003.11.003","article-title":"A comparative study on growth limits of Listeria monocytogenes as affected by temperature, pH and aw when grown in suspension or on a solid surface","volume":"21","author":"Koutsoumanis","year":"2004","journal-title":"Food Microbiol"},{"key":"10.1111\/lam.12314-BIB0015|lam12314-cit-0015","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1139\/m81-105","article-title":"The influence of nutrition and temperature on the growth of colonies of Escherichia coli K12","volume":"27","author":"Lewis","year":"1981","journal-title":"Can J Microbiol"},{"key":"10.1111\/lam.12314-BIB0016|lam12314-cit-0016","doi-asserted-by":"crossref","first-page":"3432","DOI":"10.1128\/AEM.68.7.3432-3441.2002","article-title":"Modeling the interactions of Lactobacillus curvatus colonies in solid medium: consequences for food quality and safety","volume":"68","author":"Malakar","year":"2002","journal-title":"Appl Environ Microbiol"},{"key":"10.1111\/lam.12314-BIB0017|lam12314-cit-0017","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1111\/j.1365-2672.1995.tb03148.x","article-title":"The effect of sodium chloride concentration and pH on the growth of Salmonella typhimurium colonies on solid medium","volume":"79","author":"McKay","year":"1995","journal-title":"J Appl Bacteriol"},{"key":"10.1111\/lam.12314-BIB0018|lam12314-cit-0018","first-page":"21","volume-title":"Modeling Microbial Responses on Foods","author":"McKellar","year":"2004"},{"key":"10.1111\/lam.12314-BIB0019|lam12314-cit-0019","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1002\/(SICI)1097-0061(19990915)15:12<1159::AID-YEA441>3.0.CO;2-D","article-title":"Saccharomyces cerevisiae colony growth and ageing: biphasic growth accompanied by changes in gene expression","volume":"15","author":"Meunier","year":"1999","journal-title":"Yeast"},{"key":"10.1111\/lam.12314-BIB0020|lam12314-cit-0020","first-page":"732","article-title":"The estimation of the bacteriocidal power of blood","volume":"38","author":"Miles","year":"1938","journal-title":"J Hyg"},{"key":"10.1111\/lam.12314-BIB0021|lam12314-cit-0021","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1042\/BJ20120312","article-title":"The transport of carboxylic acids and important role of the Jen1p transporter during the development of yeast colonies","volume":"454","author":"Paiva","year":"2013","journal-title":"Biochem J"},{"key":"10.1111\/lam.12314-BIB0022|lam12314-cit-0022","doi-asserted-by":"crossref","first-page":"3901","DOI":"10.1091\/mbc.e01-12-0149","article-title":"Ammonia pulses and metabolic oscillations guide yeast colony development","volume":"13","author":"Palkov\u00e1","year":"2002","journal-title":"Mol Biol Cell"},{"key":"10.1111\/lam.12314-BIB0023|lam12314-cit-0023","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1080\/09687680902893130","article-title":"Synchronous plasma membrane electrochemical potential oscillations during yeast colony development and aging","volume":"26","author":"Palkov\u00e1","year":"2009","journal-title":"Mol Membr Biol"},{"key":"10.1111\/lam.12314-BIB0024|lam12314-cit-0024","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1099\/00221287-66-2-137","article-title":"Growth measurements on surface colonies of bacteria","volume":"66","author":"Palumbo","year":"1971","journal-title":"J Gen Microbiol"},{"key":"10.1111\/lam.12314-BIB0025|lam12314-cit-0025","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1023\/A:1017998232677","article-title":"Nonlinearity in the growth of bacterial colonies: conditions and causes","volume":"71","author":"Panikov","year":"2002","journal-title":"Microbiology"},{"key":"10.1111\/lam.12314-BIB0026|lam12314-cit-0026","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1039\/b708241j","article-title":"Spatial-temporal modelling of bacterial colony growth on solid media","volume":"4","author":"Pipe","year":"2008","journal-title":"Mol BioSyst"},{"key":"10.1111\/lam.12314-BIB0027|lam12314-cit-0027","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1099\/00221287-47-2-181","article-title":"A kinetic study of the mode of growth of surface colonies of bacteria and fungi","volume":"47","author":"Pirt","year":"1967","journal-title":"J Gen Microbiol"},{"key":"10.1111\/lam.12314-BIB0028|lam12314-cit-0028","first-page":"276","volume-title":"Principles of Microbe and Cell Cultivation","author":"Pirt","year":"1975"},{"key":"10.1111\/lam.12314-BIB0029|lam12314-cit-0029","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1099\/00221287-111-2-399","article-title":"Autoradiographic study of the localization and evolution of growth zones in bacterial colonies","volume":"111","author":"Reyrolle","year":"1979","journal-title":"J Gen Microbiol"},{"key":"10.1111\/lam.12314-BIB0030|lam12314-cit-0030","first-page":"485","article-title":"A two-dimensional model of the colony growth unicellular microorganisms and its experimental testing","volume":"64","author":"Rodin","year":"1995","journal-title":"Mikrobiologiya"},{"key":"10.1111\/lam.12314-BIB0031|lam12314-cit-0031","first-page":"403","article-title":"Simplified model of increase in colony diameter during growth of unicellular microorganisms and its use in evaluating the effect of biocides on microbial cells","volume":"34","author":"Rodin","year":"1998","journal-title":"Appl Biochem Microbiol"},{"key":"10.1111\/lam.12314-BIB0032|lam12314-cit-0032","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/j.femsyr.2004.09.002","article-title":"Differential detection of Debaryomyces hansenii isolated from intermediate-moisture foods by PCR-RFLP of the IGS region of rDNA","volume":"5","author":"Romero","year":"2005","journal-title":"FEMS Yeast Res"},{"key":"10.1111\/lam.12314-BIB0033|lam12314-cit-0033","first-page":"501","article-title":"Indices for performance evaluation of predictive models in food microbiology","volume":"81","author":"Ross","year":"1996","journal-title":"J Appl Bacteriol"},{"key":"10.1111\/lam.12314-BIB0034|lam12314-cit-0034","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1046\/j.1365-2672.2000.00984.x","article-title":"Evaluation of plate count methods for determination of maximum specific growth rate in mixed microbial communities, and its possible application for diversity assessment","volume":"88","author":"Salvesen","year":"2000","journal-title":"J Appl Microbiol"},{"key":"10.1111\/lam.12314-BIB0035|lam12314-cit-0035","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1111\/j.1365-2672.2007.03358.x","article-title":"Image analysis as a mean to model growth of Escherichia coli O157:H7 in gel cassettes","volume":"103","author":"Skandamis","year":"2007","journal-title":"J Appl Microbiol"},{"key":"10.1111\/lam.12314-BIB0036|lam12314-cit-0036","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.ijfoodmicro.2008.06.031","article-title":"Effect of pH, water activity and gel micro-structure, including oxygen profiles and rheological characterization, on the growth kinetics of Salmonella typhimurium","volume":"128","author":"Theys","year":"2008","journal-title":"Int J Food Microbiol"},{"key":"10.1111\/lam.12314-BIB0037|lam12314-cit-0037","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1111\/j.1365-2672.2009.04256.x","article-title":"Evaluation of a mathematical model structure describing the effect of (gel) structure on the growth of Listeria innocua, Lactococcus lactis and Salmonella typhimurium","volume":"107","author":"Theys","year":"2009","journal-title":"J Appl Microbiol"},{"key":"10.1111\/lam.12314-BIB0038|lam12314-cit-0038","doi-asserted-by":"crossref","first-page":"e46243","DOI":"10.1371\/journal.pone.0046243","article-title":"Transcriptional profiling of a yeast colony provides new insight into the heterogeneity of multicellular fungal communities","volume":"7","author":"Traven","year":"2012","journal-title":"PLoS ONE"},{"key":"10.1111\/lam.12314-BIB0039|lam12314-cit-0039","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1083\/jcb.200410064","article-title":"Physiological regulation of yeast cell death in multicelular colonies is triggered by ammonia","volume":"169","author":"V\u00e1chov\u00e1","year":"2005","journal-title":"J Cell Biol"},{"key":"10.1111\/lam.12314-BIB0040|lam12314-cit-0040","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1042\/BST0391471","article-title":"Aging and longevity of yeast colony populations: metabolic adaptation and differentiation","volume":"39","author":"V\u00e1chov\u00e1","year":"2011","journal-title":"Biochem Soc Trans"},{"key":"10.1111\/lam.12314-BIB0041|lam12314-cit-0041","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/601836","article-title":"Yeast colonies: a model for studies of aging, environmental adaptation, and longevity","volume":"2012","author":"V\u00e1chov\u00e1","year":"2012","journal-title":"Oxid Med Cell Longev"},{"key":"10.1111\/lam.12314-BIB0042|lam12314-cit-0042","doi-asserted-by":"crossref","first-page":"2214","DOI":"10.1016\/j.bpj.2014.02.040","article-title":"Growing yeast into cylindrical colonies","volume":"106","author":"Vulin","year":"2014","journal-title":"Biophys J"},{"key":"10.1111\/lam.12314-BIB0043|lam12314-cit-0043","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1111\/j.1365-2672.1997.tb02869.x","article-title":"The effect of growth dynamics upon pH gradient formation within and around subsurface colonies of Salmonella Typhimurium","volume":"82","author":"Walker","year":"1997","journal-title":"J Appl Microbiol"},{"key":"10.1111\/lam.12314-BIB0044|lam12314-cit-0044","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1007\/s00449-010-0442-6","article-title":"Applying dimorphic yeasts as model organisms to study mycelial growth: part 1. Experimental investigation of the spatio-temporal development of filamentous yeast colonies","volume":"34","author":"Walther","year":"2011","journal-title":"Bioprocess Biosyst Eng"},{"key":"10.1111\/lam.12314-BIB0045|lam12314-cit-0045","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/S0168-1605(01)00660-2","article-title":"Modeling microbial growth in structured foods: towards a unified approach","volume":"73","author":"Wilson","year":"2002","journal-title":"Int J Food Microbiol"},{"key":"10.1111\/lam.12314-BIB0046|lam12314-cit-0046","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/0168-1605(95)00065-8","article-title":"Submerged bacterial colonies within food and model systems: their growth, distribution and interactions","volume":"28","author":"Wimpenny","year":"1995a","journal-title":"Int J Food Microbiol"},{"key":"10.1111\/lam.12314-BIB0047|lam12314-cit-0047","first-page":"14","article-title":"Monitoring microbial colony growth using image analysis techniques","volume":"7","author":"Wimpenny","year":"1995b","journal-title":"Binary"},{"key":"10.1111\/lam.12314-BIB0048|lam12314-cit-0048","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.ijfoodmicro.2010.06.007","article-title":"Strain typing of Zygosaccharomyces yeast species using a single molecular method based on polymorphism of the intergenic spacer region (IGS)","volume":"142","author":"Wrent","year":"2010","journal-title":"Int J Food Microbiol"}],"container-title":["Letters in Applied Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Flam.12314","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Flam.12314","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/lam.12314\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,14]],"date-time":"2023-02-14T15:02:03Z","timestamp":1676386923000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/lambio\/article\/59\/6\/594\/6700006"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,9,18]]},"references-count":48,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2014,12]]}},"URL":"https:\/\/doi.org\/10.1111\/lam.12314","archive":["Portico"],"relation":{},"ISSN":["0266-8254"],"issn-type":[{"value":"0266-8254","type":"print"}],"subject":[],"published":{"date-parts":[[2014,9,18]]}}}