{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T13:48:45Z","timestamp":1789480125434,"version":"build-2803163510"},"reference-count":22,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2022,11,24]],"date-time":"2022-11-24T00:00:00Z","timestamp":1669248000000},"content-version":"vor","delay-in-days":633,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/100005825","name":"National Institute of Food and Agriculture","doi-asserted-by":"publisher","award":["2016-68003-24607"],"award-info":[{"award-number":["2016-68003-24607"]}],"id":[{"id":"10.13039\/100005825","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000199","name":"United States Department of Agriculture","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000199","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The transfer of antimicrobial resistance genes commonly occurs via vertical and horizontal gene transfer, as such genes are often found on the same mobile genetic element. This occurrence can lead to the co-selection of resistance to antimicrobials without their application. Dairy cattle located in the south-western United States were enrolled in a matched-pair longitudinal study to evaluate the effects of a two-dose ceftiofur treatment for metritis on levels of third-generation cephalosporin resistance among faecal Escherichia coli temporally. Escherichia coli chosen for further investigation were isolated on selective media, harboured extended-spectrum beta-lactam, fluoroquinolone and macrolide resistance genes. This combination has previously been unreported; importantly, it included genes encoding for resistance to antibiotics that can only be used in dairy cattle less than 20 months of age. Fluoroquinolones, macrolides and third and higher generation cephalosporins are considered critically important and highest priority for human medicine by the World Health Organization.<\/jats:p>","DOI":"10.1111\/lam.13419","type":"journal-article","created":{"date-parts":[[2020,10,24]],"date-time":"2020-10-24T13:04:16Z","timestamp":1603544656000},"page":"220-224","source":"Crossref","is-referenced-by-count":20,"title":["Use of critically important antimicrobial classes early in life may adversely impact bacterial resistance profiles during adult years: potential co-selection for plasmid-borne fluoroquinolone and macrolide resistance via extended-spectrum beta-lactam use in dairy cattle"],"prefix":"10.1093","volume":"72","author":[{"given":"E.A.","family":"Taylor","sequence":"first","affiliation":[{"name":"Department of Veterinary Pathobiology Texas A&M University College Station TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Ossa-Trujillo","sequence":"additional","affiliation":[{"name":"Department of Veterinary Pathobiology Texas A&M University College Station TX USA"},{"name":"Department of Science Universidad del Bosque Bogota DC Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Vinasco","sequence":"additional","affiliation":[{"name":"Department of Veterinary Pathobiology Texas A&M University College Station TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.R.","family":"Jordan","sequence":"additional","affiliation":[{"name":"Department of Animal Science Texas A&M University Dallas TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.A.","family":"Garc\u00eda Buitrago","sequence":"additional","affiliation":[{"name":"Department of Animal Science New Mexico State University Clovis NM USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Hagevoort","sequence":"additional","affiliation":[{"name":"Department of Animal Science New Mexico State University Clovis NM USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.N.","family":"Norman","sequence":"additional","affiliation":[{"name":"Department of Veterinary Integrative Biosciences Texas A&M University College Station TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9154-8909","authenticated-orcid":false,"given":"S.D.","family":"Lawhon","sequence":"additional","affiliation":[{"name":"Department of Veterinary Pathobiology Texas A&M University College Station TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.M.","family":"Pi\u00f1eiro","sequence":"additional","affiliation":[{"name":"Department of Animal Science Texas A&M University Amarillo TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Levent","sequence":"additional","affiliation":[{"name":"Department of Veterinary Pathobiology Texas A&M University College Station TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0538-5961","authenticated-orcid":false,"given":"H.M.","family":"Scott","sequence":"additional","affiliation":[{"name":"Department of Veterinary Pathobiology Texas A&M University College Station TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2021,3,1]]},"reference":[{"key":"2023020108352859000_lam13419-bib-0001","doi-asserted-by":"crossref","first-page":"1954","DOI":"10.1007\/s11356-015-5609-x","article-title":"Quinolone co-resistance in ESBL-or AmpC-producing Escherichia coli from an Indian urban aquatic environment and their public health implications","volume":"23","author":"Bajaj","year":"2016","journal-title":"Environ Sci Pollut Res Int"},{"key":"2023020108352859000_lam13419-bib-0002","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1089\/cmb.2012.0021","article-title":"SPAdes: a new genome assembly algorithm and its applications to single-cell sequencing","volume":"19","author":"Bankevich","year":"2012","journal-title":"J Comput Biol"},{"key":"2023020108352859000_lam13419-bib-0003","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/j.coph.2011.07.007","article-title":"Co-resistance: an opportunity for the bacteria and resistance genes","volume":"11","author":"Cant\u00f3n","year":"2011","journal-title":"Curr Opin Pharmacol"},{"key":"2023020108352859000_lam13419-bib-0004","doi-asserted-by":"crossref","first-page":"3895","DOI":"10.1128\/AAC.02412-14","article-title":"In silico detection and typing of plasmids using PlasmidFinder and plasmid multilocus sequence typing","volume":"58","author":"Carattoli","year":"2014","journal-title":"Antimicrob Agents Chemother"},{"key":"2023020108352859000_lam13419-bib-0005","volume-title":"Performance Standards for Antimicrobial Susceptibility Testing","author":"Clinical and Laboratory Standards Institute","year":"2020"},{"key":"2023020108352859000_lam13419-bib-0006","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1128\/AAC.01750-12","article-title":"blaCTX-M-32 on an IncN plasmid in Escherichia coli from beef cattle in the United States","volume":"57","author":"Cottell","year":"2013","journal-title":"Antimicrob Agents Chemother"},{"key":"2023020108352859000_lam13419-bib-0007","doi-asserted-by":"crossref","first-page":"6387","DOI":"10.3168\/jds.2015-9453","article-title":"Risk factors for quinolone-resistant Escherichia coli in feces from preweaned dairy calves and postpartum dairy cows","volume":"98","author":"Duse","year":"2015","journal-title":"J Dairy Sci"},{"key":"2023020108352859000_lam13419-bib-0008","doi-asserted-by":"crossref","first-page":"3765","DOI":"10.1128\/AEM.03061-15","article-title":"Occurrence and spread of Quinolone-resistant Escherichia coli on dairy farms","volume":"82","author":"Duse","year":"2016","journal-title":"Appl Environ Microbiol"},{"key":"2023020108352859000_lam13419-bib-0009","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1186\/s13073-014-0090-6","article-title":"SRST2: rapid genomic surveillance for public health and hospital microbiology labs","volume":"6","author":"Inouye","year":"2014","journal-title":"Genome Med"},{"key":"2023020108352859000_lam13419-bib-0010","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1128\/AAC.50.4.1178-1182.2006","article-title":"qnrB, another plasmid-mediated gene for quinolone resistance","volume":"50","author":"Jacoby","year":"2006","journal-title":"Antimicrob Agents Chemother"},{"key":"2023020108352859000_lam13419-bib-0011","doi-asserted-by":"crossref","first-page":"4552","DOI":"10.1128\/AEM.00373-12","article-title":"Variable within-and between-herd diversity of CTX-M cephalosporinase-bearing Escherichia coli isolates from dairy cattle","volume":"78","author":"Mollenkopf","year":"2012","journal-title":"Appl Environ Microbiol"},{"key":"2023020108352859000_lam13419-bib-0012","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1093\/jac\/dki245","article-title":"Emergence of plasmid-mediated resistance to quinolones in Enterobacteriaceae","volume":"56","author":"Nordmann","year":"2005","journal-title":"J Antimicrob Chemother"},{"key":"2023020108352859000_lam13419-bib-0013","doi-asserted-by":"crossref","first-page":"713","DOI":"10.15585\/mmwr.mm6833a1","article-title":"Outbreak of Salmonella Newport infections with decreased susceptibility to azithromycin linked to beef obtained in the United States and soft cheese obtained in Mexico\u2014United States, 2018\u20132019","volume":"68","author":"Plumb","year":"2019","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"2023020108352859000_lam13419-bib-0014","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1038\/nm1347","article-title":"Fluoroquinolone-modifying enzyme: a new adaptation of a common aminoglycoside acetyltransferase","volume":"12","author":"Robicsek","year":"2006","journal-title":"Nat Med"},{"key":"2023020108352859000_lam13419-bib-0015","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1089\/fpd.2018.2579","article-title":"Diversity of extended-spectrum cephalosporin-resistant Escherichia coli in feces from calves and cows on Pennsylvania dairy farms","volume":"16","author":"Salaheen","year":"2019","journal-title":"Foodborne Pathog Dis"},{"key":"2023020108352859000_lam13419-bib-0016","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0220068","article-title":"Effects of two-dose ceftiofur treatment for metritis on the temporal dynamics of antimicrobial resistance among fecal Escherichia coli in Holstein-Friesian dairy cows","volume":"14","author":"Taylor","year":"2019","journal-title":"PLoS One"},{"key":"2023020108352859000_lam13419-bib-0017","volume-title":"The National Antimicrobial Resistance Monitoring System: NARMS Integrated Report, 2016\u20132017","author":"U.S. Department of Health and Human Services, FDA","year":"2019"},{"key":"2023020108352859000_lam13419-bib-0018","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1128\/AAC.37.1.126","article-title":"A single point mutation in the DNA gyrase A protein greatly reduces binding of fluoroquinolones to the gyrase-DNA complex","volume":"37","author":"Willmott","year":"1993","journal-title":"Antimicrob Agents Chemother"},{"key":"2023020108352859000_lam13419-bib-0019","doi-asserted-by":"crossref","first-page":"1575","DOI":"10.1089\/fpd.2010.0615","article-title":"CTX-M-type extended-spectrum \u03b2-lactamases present in Escherichia coli from the feces of cattle in Ohio, United States","volume":"7","author":"Wittum","year":"2010","journal-title":"Foodborne Pathog Dis"},{"key":"2023020108352859000_lam13419-bib-0020","volume-title":"WHO list of Critically Important Antimicrobials for Human Medicine List","author":"World Health Organization","year":"2019"},{"key":"2023020108352859000_lam13419-bib-0021","doi-asserted-by":"crossref","first-page":"2640","DOI":"10.1093\/jac\/dks261","article-title":"Identification of acquired antimicrobial resistance genes","volume":"67","author":"Zankari","year":"2012","journal-title":"J Antimicrob Chemother"},{"key":"2023020108352859000_lam13419-bib-0022","doi-asserted-by":"crossref","first-page":"79","DOI":"10.3109\/1040841X.2012.691460","article-title":"Epidemiology and genetics of CTX-M extended-spectrum \u03b2-lactamases in Gram-negative bacteria","volume":"39","author":"Zhao","year":"2013","journal-title":"Crit Rev Microbiol"}],"container-title":["Letters in Applied Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/lam.13419","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/lam.13419","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/am-pdf\/10.1111\/lam.13419","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/lambio\/article-pdf\/72\/3\/220\/49000550\/lambio0220.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/lambio\/article-pdf\/72\/3\/220\/49000550\/lambio0220.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,14]],"date-time":"2023-02-14T09:36:12Z","timestamp":1676367372000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/lambio\/article\/72\/3\/220\/6698320"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,1]]},"references-count":22,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,3,1]]}},"URL":"https:\/\/doi.org\/10.1111\/lam.13419","relation":{},"ISSN":["1472-765X","0266-8254"],"issn-type":[{"value":"1472-765X","type":"electronic"},{"value":"0266-8254","type":"print"}],"subject":[],"published-other":{"date-parts":[[2021,3,1]]},"published":{"date-parts":[[2021,3,1]]}}}