{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T17:52:03Z","timestamp":1790099523100,"version":"4.0.1"},"reference-count":35,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2013,12,3]],"date-time":"2013-12-03T00:00:00Z","timestamp":1386028800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Liver International"],"published-print":{"date-parts":[[2014,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background &amp; Aims<\/jats:title><jats:p>The most serious complication of acute mesenteric vein thrombosis (<jats:styled-content style=\"fixed-case\">MVT<\/jats:styled-content>) is acute intestinal ischaemia requiring intestinal resection or causing death. Risk factors for this complication are unknown. To identify risk factors for severe intestinal ischaemia leading to intestinal resection in patients with acute <jats:styled-content style=\"fixed-case\">MVT<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively analysed consecutive patients seen between 2002 and 2012 with acute <jats:styled-content style=\"fixed-case\">MVT<\/jats:styled-content> in 2 specialized units. Patients with cirrhosis were excluded. We compared patients who required intestinal resection to patients who did not.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among 57 patients, a local risk factor was identified in 14 (24%) patients, oral contraceptive use in 16 (29%), and at least one or more other systemic prothrombotic condition in 25 (44%). Five (9%) patients had diabetes mellitus (<jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content>), 33 (58%) had overweight or obesity, 9 (18%) had hypertriglyceridemia and 10 (19%) had arterial hypertension. Eleven patients (19%) underwent intestinal resection. <jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content> was significantly associated with intestinal resection (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.02) while local factors or prothrombotic conditions were not. Computed tomography (<jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content>) scans performed at diagnosis found that occlusion of second order radicles of the superior mesenteric vein was more frequently observed in patients who underwent intestinal resection (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.009).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In acute <jats:styled-content style=\"fixed-case\">MVT<\/jats:styled-content>, patients with underlying <jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content> have an increased risk of requiring intestinal resection. Neither local factors nor systemic prothrombotic conditions are associated with intestinal resection. When <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> scan shows the preservation of second order radicles of the superior mesenteric vein, the risk of severe resection is low.<\/jats:p><\/jats:sec>","DOI":"10.1111\/liv.12386","type":"journal-article","created":{"date-parts":[[2013,11,15]],"date-time":"2013-11-15T05:55:13Z","timestamp":1384494913000},"page":"1314-1321","source":"Crossref","is-referenced-by-count":54,"title":["Type 2 diabetes mellitus as a risk factor for intestinal resection in patients with superior mesenteric vein thrombosis"],"prefix":"10.1111","volume":"34","author":[{"given":"Laure","family":"Elkrief","sequence":"first","affiliation":[{"name":"Service d'H\u00e9patologie H\u00f4pital Beaujon and INSERM U773 Clichy France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier","family":"Corcos","sequence":"additional","affiliation":[{"name":"Service de Gastroent\u00e9rologie et d'assistance nutritive H\u00f4pital Beaujon Clichy 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