{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T19:53:17Z","timestamp":1767988397047,"version":"3.49.0"},"reference-count":23,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2014,3,15]],"date-time":"2014-03-15T00:00:00Z","timestamp":1394841600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Liver International"],"published-print":{"date-parts":[[2014,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background &amp; Aims<\/jats:title><jats:p>Non\u2010ischaemic cardiomyopathy (<jats:styled-content style=\"fixed-case\">NIC<\/jats:styled-content>) is an early complication of liver transplantation (<jats:styled-content style=\"fixed-case\">LT<\/jats:styled-content>). Our aims were to define the prevalence, associated clinical factors, and prognosis of this condition.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective study was performed on patients undergoing<jats:styled-content style=\"fixed-case\">LT<\/jats:styled-content>at our institution from January 2005 to December 2012. Patients who developed<jats:styled-content style=\"fixed-case\">NIC<\/jats:styled-content>were identified. Data collected included demographic and clinical data.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total 1460 transplants were performed in this period and seventeen patients developed<jats:styled-content style=\"fixed-case\">NIC<\/jats:styled-content>. Pretransplant median<jats:styled-content style=\"fixed-case\">QT<\/jats:styled-content>c interval was 459 (range, 405\u2013530), and median E\/A ratio was 1 (range, 0.71\u20131.67). Fourteen patients (82%) were severely malnourished and required nutritional support. Thirteen patients (76%) had renal insufficiency. Median time to onset was 2\u00a0days post\u2010transplant (range, 0\u201320). Echocardiograms showed global left ventricular hypokinesis and a decrease in ejection fraction (<jats:styled-content style=\"fixed-case\">EF<\/jats:styled-content>) from a median of 65% (range, 50\u201381) pretransplant to a median of 21% (range, 15\u201332). Median raw model for end\u2010stage liver disease (<jats:styled-content style=\"fixed-case\">MELD<\/jats:styled-content>) score was 29 in patients with<jats:styled-content style=\"fixed-case\">NIC<\/jats:styled-content>vs. 18 in patients without cardiomyopathy (<jats:italic>P\u00a0<\/jats:italic>=\u00a00.01). There was no significant difference between recipients with<jats:styled-content style=\"fixed-case\">NIC<\/jats:styled-content>vs. recipients without cardiomyopathy regarding donor age, donor risk index, and cold and warm ischaemia time. Recovery of cardiac function occurred in 16 patients, with a median<jats:styled-content style=\"fixed-case\">EF<\/jats:styled-content>of 44% (range, 25\u201365%) at the time of discharge. The last echocardiogram available showed a median<jats:styled-content style=\"fixed-case\">EF<\/jats:styled-content>of 59% (range, 49\u201373%). One\u2010year survival of NIC patients was 94.1%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Non\u2010ischaemic cardiomyopathy is a rare complication after<jats:styled-content style=\"fixed-case\">LT<\/jats:styled-content>. Patients with<jats:styled-content style=\"fixed-case\">NIC<\/jats:styled-content>are critically ill, with high<jats:styled-content style=\"fixed-case\">MELD<\/jats:styled-content>score, and severe malnutrition.<\/jats:p><\/jats:sec>","DOI":"10.1111\/liv.12501","type":"journal-article","created":{"date-parts":[[2014,2,17]],"date-time":"2014-02-17T11:26:52Z","timestamp":1392636412000},"source":"Crossref","is-referenced-by-count":17,"title":["Reversible non\u2010ischaemic cardiomyopathy and left ventricular dysfunction after liver transplantation: a single\u2010centre experience"],"prefix":"10.1111","volume":"34","author":[{"given":"Maria L.","family":"Yataco","sequence":"first","affiliation":[{"name":"Department of Transplantation Mayo Clinic Florida Jacksonville FL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Difato","sequence":"additional","affiliation":[{"name":"Department of Transplantation Mayo Clinic Florida Jacksonville FL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johannes","family":"Bargehr","sequence":"additional","affiliation":[{"name":"Department of Transplantation Mayo Clinic Florida Jacksonville FL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barry G.","family":"Rosser","sequence":"additional","affiliation":[{"name":"Department of Transplantation Mayo Clinic Florida Jacksonville FL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tushar","family":"Patel","sequence":"additional","affiliation":[{"name":"Department of Transplantation Mayo Clinic Florida Jacksonville FL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jorge F.","family":"Trejo\u2010Gutierrez","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Diseases Mayo Clinic Florida Jacksonville FL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Surakit","family":"Pungpapong","sequence":"additional","affiliation":[{"name":"Department of Transplantation Mayo Clinic Florida Jacksonville FL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. Burcin","family":"Taner","sequence":"additional","affiliation":[{"name":"Department of Transplantation Mayo Clinic Florida Jacksonville FL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaime","family":"Aranda\u2010Michel","sequence":"additional","affiliation":[{"name":"Department of Transplantation Mayo Clinic Florida Jacksonville FL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,3,15]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1111\/j.1399-0012.1995.tb00368.x","article-title":"Cardiovascular complications following liver transplantation","volume":"9","author":"Dec G","year":"1995","journal-title":"Clin Transplant"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1053\/jlts.2001.27084"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.03.026"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2010.11.003"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2007.08.056"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.500040513"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.21822"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.23654"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2012.09.089"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.20766"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1053\/jhep.2003.50447"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2010.02.023"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.510270106"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.23723"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2010.03.097"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1499-3872(11)60123-9"},{"key":"e_1_2_7_18_1","first-page":"1248a","article-title":"Cirrhotic cardiomyopathy: frequency, characteristics and relationship with bacterial translocation","volume":"54","author":"Karagiannakis D","year":"2011","journal-title":"Hepatology"},{"key":"e_1_2_7_19_1","first-page":"475a","article-title":"Prevalence of diastolic dysfunction in cirrhosis, and its clinical significance","volume":"54","author":"Wong F","year":"2011","journal-title":"Hepatology"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.121.5.1638"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2012.07.037"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1478-3231.2009.02062.x"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nut.2009.11.017"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/MCO.0b013e328341ed93"}],"container-title":["Liver International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fliv.12501","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fliv.12501","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/liv.12501","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T21:33:30Z","timestamp":1746135210000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/liv.12501"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,3,15]]},"references-count":23,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2014,7]]}},"alternative-id":["10.1111\/liv.12501"],"URL":"https:\/\/doi.org\/10.1111\/liv.12501","archive":["Portico"],"relation":{},"ISSN":["1478-3223","1478-3231"],"issn-type":[{"value":"1478-3223","type":"print"},{"value":"1478-3231","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,3,15]]}}}