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A standardized questionnaire and abdominal ultrasonography were used to diagnose <jats:styled-content style=\"fixed-case\">NAFLD<\/jats:styled-content>. A cut\u2010off point of <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> 23\u00a0kg\/m<jats:sup>2<\/jats:sup> was used to define overweight (\u226523.0\u00a0kg\/m<jats:sup>2<\/jats:sup>) or non\u2010overweight (&lt;23.0\u00a0kg\/m<jats:sup>2<\/jats:sup>). The primary outcome was incident T2<jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Over a mean follow\u2010up of 12.8\u00a0years, 351 participants (7.6%) developed T2<jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content>. The incidence rate of T2<jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content> was 3.2% in the non\u2010overweight without <jats:styled-content style=\"fixed-case\">NAFLD<\/jats:styled-content> group, 14.4% in the non\u2010overweight with <jats:styled-content style=\"fixed-case\">NAFLD<\/jats:styled-content> group, 8.0% in the overweight without <jats:styled-content style=\"fixed-case\">NAFLD<\/jats:styled-content> group and 26.4% in the overweight with <jats:styled-content style=\"fixed-case\">NAFLD<\/jats:styled-content> group. The adjusted hazard ratios for incident T2<jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content> compared with the non\u2010overweight without <jats:styled-content style=\"fixed-case\">NAFLD<\/jats:styled-content> group were as follows: 3.59 (95% CI: 2.14\u20135.76) in the non\u2010overweight with <jats:styled-content style=\"fixed-case\">NAFLD<\/jats:styled-content> group, 1.99 (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 1.47\u20132.69) in the overweight without <jats:styled-content style=\"fixed-case\">NAFLD<\/jats:styled-content> group and 6.77 (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 5.17\u20138.91) in the overweight with <jats:styled-content style=\"fixed-case\">NAFLD<\/jats:styled-content> group. The adjusted hazard ratio in the non\u2010overweight with <jats:styled-content style=\"fixed-case\">NAFLD<\/jats:styled-content> group was significantly higher than that in the overweight without <jats:styled-content style=\"fixed-case\">NAFLD<\/jats:styled-content> group or that in the non\u2010overweight without <jats:styled-content style=\"fixed-case\">NAFLD<\/jats:styled-content> group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Non\u2010overweight individuals with <jats:styled-content style=\"fixed-case\">NAFLD<\/jats:styled-content> had a high risk of incident T2<jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content>. Diagnosis of <jats:styled-content style=\"fixed-case\">NAFLD<\/jats:styled-content> is important in non\u2010overweight individuals, and therefore it might be necessary to follow their health conditions on a long\u2010term basis after detection of <jats:styled-content style=\"fixed-case\">NAFLD<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/liv.12912","type":"journal-article","created":{"date-parts":[[2015,7,14]],"date-time":"2015-07-14T21:55:01Z","timestamp":1436910901000},"page":"275-283","source":"Crossref","is-referenced-by-count":122,"title":["The impact of non\u2010alcoholic fatty liver disease on incident type 2 diabetes mellitus in non\u2010overweight individuals"],"prefix":"10.1111","volume":"36","author":[{"given":"Takuya","family":"Fukuda","sequence":"first","affiliation":[{"name":"Department of Endocrinology and Metabolism Kyoto Prefectural University of Medicine Graduate School of Medical Science Kyoto 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