{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T10:40:49Z","timestamp":1764240049247,"version":"3.37.3"},"reference-count":16,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,2,27]],"date-time":"2017-02-27T00:00:00Z","timestamp":1488153600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Liver International"],"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Although liver transplantation has become accepted as a life\u2010saving treatment of last resort for most life\u2010threatening liver disorders, the use of liver transplantation to rescue patients with severe alcoholic hepatitis unresponsive to medical therapy remains controversial. I propose the concepts that alcohol use disorder is an illness, that on occasion results in alcoholic liver disease and that treatment of alcoholic liver disease, including treatment of patients with severe alcoholic hepatitis, combines treatment of the alcohol use disorder and of alcoholic liver disease. From this I derive the following principal to govern selection of patients for liver transplantation of patients with alcohol use disorder: that alcohol use disorder should impact suitability for liver transplantation as a co\u2010morbid disorder, in the same way as other common co\u2010morbid disorders such as diabetes mellitus or systemic hypertension, are factored in the selection process. We should relate the risk of drinking relapse to the prognosis of the patient after transplantation, rather than in a binary construct of likelihood of maintaining abstinence vs drinking.<\/jats:p>","DOI":"10.1111\/liv.13343","type":"journal-article","created":{"date-parts":[[2017,2,27]],"date-time":"2017-02-27T14:26:19Z","timestamp":1488205579000},"page":"343-344","source":"Crossref","is-referenced-by-count":14,"title":["Liver transplantation for severe alcoholic hepatitis\u2013 The PRO view"],"prefix":"10.1111","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0380-7980","authenticated-orcid":false,"given":"Michael R.","family":"Lucey","sequence":"first","affiliation":[{"name":"Division of Gastroenterology and Hepatology University of Wisconsin School of Medicine and Public Health  Madison WI USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,2,27]]},"reference":[{"key":"e_1_2_4_2_1","first-page":"135","article-title":"Studies on the rejection of the transplanted homologous dog liver","volume":"112","author":"Starzl TE","year":"1961","journal-title":"Surg Gynecol Obstet."},{"key":"e_1_2_4_3_1","unstructured":"Anonymous.www.UNOS.org. Accessed October 16 2016."},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2013.03.007"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(68)90111-3"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/apt.12427"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8278(86)80006-X"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.317.7152.172"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-155-8-201110180-00006"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2010.03232.x"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrgastro.2013.247"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.23762"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2015.204"},{"key":"e_1_2_4_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOT.0b013e32835fb94b"},{"key":"e_1_2_4_15_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1105703"},{"key":"e_1_2_4_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.13586"},{"key":"e_1_2_4_17_1","first-page":"29","volume-title":"Liver Transplantation and the Alcoholic Patient","author":"Beresford TP","year":"1994"}],"container-title":["Liver International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fliv.13343","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/liv.13343","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T18:56:45Z","timestamp":1695495405000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/liv.13343"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2,27]]},"references-count":16,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2017,3]]}},"alternative-id":["10.1111\/liv.13343"],"URL":"https:\/\/doi.org\/10.1111\/liv.13343","archive":["Portico"],"relation":{},"ISSN":["1478-3223","1478-3231"],"issn-type":[{"type":"print","value":"1478-3223"},{"type":"electronic","value":"1478-3231"}],"subject":[],"published":{"date-parts":[[2017,2,27]]}}}