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By increasing portal blood flow, splanchnic vasodilation further aggravates portal hypertension. New pathogenic pathways are being established which might result in new therapeutic strategies. The presence of varices at endoscopy and\/or other abdominal portosystemic collaterals confirms the diagnosis of portal hypertension. The role of non\u2010invasive and imaging tests in the diagnosis and prognosis of portal hypertension has been clarified. Non\u2010selective beta\u2010blockers decrease both the risk of variceal haemorrhage and hepatic decompensation. Terlipressin, somatostatin or octreotide, in combination with early endoscopic therapy, are recommended for the treatment of acute variceal haemorrhage. Early\u00a0Transjugular intrahepatic portosystemic\u00a0shunt (TIPS) is effective as salvage therapy in acute variceal bleeding in selected patients and prevents rebleeding more effectively than endoscopic and medical therapy\u00a0resulting in an increased survival.<\/jats:p>","DOI":"10.1111\/liv.14366","type":"journal-article","created":{"date-parts":[[2020,2,20]],"date-time":"2020-02-20T10:06:36Z","timestamp":1582193196000},"page":"122-127","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":63,"title":["What's new in portal hypertension?"],"prefix":"10.1111","volume":"40","author":[{"given":"Ezequiel","family":"Mauro","sequence":"first","affiliation":[{"name":"Liver Unit Hospital Italiano Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adri\u00e1n","family":"Gadano","sequence":"additional","affiliation":[{"name":"Liver Unit Hospital Italiano Buenos Aires 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