{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T05:02:28Z","timestamp":1764133348728,"version":"3.40.5"},"reference-count":34,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2020,6,24]],"date-time":"2020-06-24T00:00:00Z","timestamp":1592956800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Liver International"],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Aims<\/jats:title><jats:p>To date, no study has explored the potential role of ElastPQ, a novel point\u2010SWE technique, in the assessment of clinically significant portal hypertension. The aim of our study was to determine a liver stiffness (LS) cut\u2010off value measured by ElastPQ and laboratory parameters that could help to identify those patients who can safely avoid screening endoscopy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Data were collected on 1422 patients who underwent ElastPQ measurement from January 2013 to January 2016 in our Department. Inclusion criteria were a LS value of \u22657\u00a0kPa, an upper gastrointestinal endoscopy within 12\u00a0months and a diagnosis of compensated chronic liver disease. Exclusion criteria were history of decompensated liver disease, evidence of porto\u2010spleno\u2010mesenteric vein thrombosis and non\u2010cirrhotic portal hypertension. Varices were graded as low\u2010risk varices (grade &lt;2) or varices needing treatment (VNT, grade \u22652).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The study included 195 patients (120 [61%] HCV, 171 [88%] Child\u2010Pugh A). Varices were present in 35% cases, with 10% prevalence of VNT. According to ROC curve analysis, LS measurement and platelet count were evaluated as predictors of VNT. Overall, 75\/195 (38%) met the \u2018BAVElastPQ\u2019 criteria (that is, LS\u00a0&lt;\u00a012\u00a0kPa and platelet count &gt;150\u00a0000\/\u03bcL). Within this group, 11\/75 (15%) had any grade of varices and only 1\/75 (1%) had VNT. The BAVElastPQ criteria gave sensitivity of 0.95, specificity of 0.42, positive predictive value of 0.15 and negative predictive value of 0.99.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The BAVElastPQ criteria correctly identified 99% of patients without VNT. By applying such criteria, we could have potentially avoided 38% of surveillance endoscopies in our cohort.<\/jats:p><\/jats:sec>","DOI":"10.1111\/liv.14558","type":"journal-article","created":{"date-parts":[[2020,6,8]],"date-time":"2020-06-08T13:09:48Z","timestamp":1591621788000},"page":"1952-1960","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Assessing Baveno VI criteria with liver stiffness measured using a new point\u2010shear wave elastography technique (BAVElastPQ study)"],"prefix":"10.1111","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5805-7953","authenticated-orcid":false,"given":"Matteo","family":"Garcovich","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Gastroenterology and Liver Diseases Fondazione Policlinico Universitario A. Gemelli IRCCS Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enrico","family":"Di Stasio","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Gastroenterology and Liver Diseases Fondazione Policlinico Universitario A. Gemelli IRCCS Rome Italy"},{"name":"Institute of Biochemistry and Clinical Biochemistry Fondazione Policlinico Universitario A. Gemelli IRCCS Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria A.","family":"Zocco","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Gastroenterology and Liver Diseases Fondazione Policlinico Universitario A. Gemelli IRCCS Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Riccardi","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Gastroenterology and Liver Diseases Fondazione Policlinico Universitario A. Gemelli IRCCS Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria E.","family":"Ainora","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Gastroenterology and Liver Diseases Fondazione Policlinico Universitario A. Gemelli IRCCS Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brigida E.","family":"Annicchiarico","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Gastroenterology and Liver Diseases Fondazione Policlinico Universitario A. Gemelli IRCCS Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giulia","family":"Gibiino","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Gastroenterology and Liver Diseases Fondazione Policlinico Universitario A. 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