{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T18:31:19Z","timestamp":1793298679870,"version":"4.5.0"},"reference-count":25,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,1,19]],"date-time":"2021-01-19T00:00:00Z","timestamp":1611014400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100006483","name":"AbbVie","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006483","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Liver International"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>BACKGROUND &amp; AIMS<\/jats:title>\n                    <jats:p>Elimination of HCV by 2030, as defined by the World Health Organization (WHO), is attainable with the availability of highly efficacious therapies. This study reports progress made in the timing of HCV elimination in 45 high\u2010income countries between 2017 and 2019.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>Disease progression models of HCV infection for each country were updated with latest data on chronic HCV prevalence, and annual diagnosis and treatment levels, assumed to remain constant in the future. Modelled outcomes were analysed to determine the year in which each country would meet the WHO 2030 elimination targets.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>Of the 45 countries studied, 11 (Australia, Canada, France, Germany, Iceland, Italy, Japan, Spain, Sweden, Switzerland, and United Kingdom) are on track to meet WHO's elimination targets by 2030; five (Austria, Malta, Netherlands, New Zealand, and South Korea) by 2040; and two (Saudi Arabia and Taiwan) by 2050. The remaining 27 countries are not expected to achieve elimination before 2050. Compared to progress in 2017, South Korea is no longer on track to eliminate HCV by 2030, three (Canada, Germany, and Sweden) are now on track, and most countries (30) saw no change.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>Assuming high\u2010income countries will maintain current levels of diagnosis and treatment, only 24% are on track to eliminate HCV by 2030, and 60% are off track by at least 20\u00a0years. If current levels of diagnosis and treatment continue falling, achieving WHO's 2030 targets will be more challenging. With less than ten years remaining, screening and treatment expansion is crucial to meet WHO's HCV elimination targets.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/liv.14779","type":"journal-article","created":{"date-parts":[[2021,1,2]],"date-time":"2021-01-02T21:35:28Z","timestamp":1609623328000},"page":"456-463","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":127,"title":["Progress towards hepatitis C virus elimination in high\u2010income countries: An updated analysis"],"prefix":"10.1111","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3843-670X","authenticated-orcid":false,"given":"Ivane","family":"Gamkrelidze","sequence":"first","affiliation":[{"name":"Center for Disease Analysis Lafayette LA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0745-7559","authenticated-orcid":false,"given":"Jean\u2010Michel","family":"Pawlotsky","sequence":"additional","affiliation":[{"name":"H\u00f4pital Henri Mondor Universit\u00e9 Paris\u2010Est, and INSERM U955 Cr\u00e9teil France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9618-2299","authenticated-orcid":false,"given":"Jeffrey V.","family":"Lazarus","sequence":"additional","affiliation":[{"name":"Barcelona Institute for Global Health (ISGlobal) Hospital Cl\u00ednic University of Barcelona Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2640-2211","authenticated-orcid":false,"given":"Jordan J.","family":"Feld","sequence":"additional","affiliation":[{"name":"Toronto Centre for Liver Disease University Health Network University of Toronto Toronto ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0845-6833","authenticated-orcid":false,"given":"Stefan","family":"Zeuzem","sequence":"additional","affiliation":[{"name":"Medizinische Klinik 1 Universit\u00e4tsklinikum Frankfurt am Main Frankfurt Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanjun","family":"Bao","sequence":"additional","affiliation":[{"name":"AbbVie Inc North Chicago IL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Gabriela Pires dos Santos","sequence":"additional","affiliation":[{"name":"AbbVie Inc North Chicago IL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7261-1933","authenticated-orcid":false,"given":"Yuri","family":"Sanchez Gonzalez","sequence":"additional","affiliation":[{"name":"AbbVie Inc North Chicago IL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2658-6930","authenticated-orcid":false,"given":"Homie","family":"Razavi","sequence":"additional","affiliation":[{"name":"Center for Disease Analysis Lafayette LA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,1,19]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(16)30181-9"},{"key":"e_1_2_7_3_1","unstructured":"WHO.Global Health Sector Strategy on Viral Hepatitis 2016\u20132021 Towards ending Viral Hepatitis. Geneva Switzerland: World Health Organization. June2016.https:\/\/www.who.int\/hepatitis\/strategy2016\u20102021\/ghss\u2010hep\/en. Accessed May 19 2020."},{"key":"e_1_2_7_4_1","unstructured":"WHO.Combating hepatitis B and C to reach elimination by 2030. Geneva Switzerland: World Health Organization. May2016.http:\/\/www.who.int\/hepatitis\/publications\/hep\u2010elimination\u2010by\u20102030\u2010brief\/en. Accessed July 25 2016."},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(18)30270-X"},{"key":"e_1_2_7_6_1","unstructured":"Probabilistic Population Projections Rev. 1 based on the World Population Prospects 2019 Rev. 1 [database on the Internet]. United Nations Department of Economic and Social Affairs Population Division.2019.http:\/\/population.un.org\/wpp\/. Accessed March 24 2020."},{"key":"e_1_2_7_7_1","unstructured":"World Bank Country and Lending Groups [database on the Internet]. The World Bank. 2019.https:\/\/datahelpdesk.worldbank.org\/knowledgebase\/articles\/906519\u2010world\u2010bank\u2010country\u2010and\u2010lending\u2010groups. Accessed September 20 2019."},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/liv.14324"},{"key":"e_1_2_7_9_1","unstructured":"Polaris Observatory [database on the Internet].CDA Foundation.2019.https:\/\/cdafound.org\/polaris. Accessed November 11 2019."},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciz714"},{"key":"e_1_2_7_11_1","unstructured":"Botande hepatit C\u2010l\u00e4kemedel subventioneras till alla patienter. Tandv\u00e5rdsoch l\u00e4kemedelsf\u00f6rm\u00e5nsverket.https:\/\/www.tlv.se\/om\u2010oss\/press\/nyheter\/arkiv\/2017\u201012\u201014\u2010botande\u2010hepatit\u2010c\u2010lakemedel\u2010subventioneras\u2010till\u2010alla\u2010patienter.html. Accessed February 24 2020."},{"key":"e_1_2_7_12_1","unstructured":"Infektionsepidemiologisches Jahrbuch meldepflichtiger Krankheiten f\u00fcr 2017"},{"key":"e_1_2_7_13_1","volume-title":"Infektionsepidemiologisches Jahrbuch meldepflichtiger Krankheiten f\u00fcr 2018"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/add.14393"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(19)30462-0"},{"key":"e_1_2_7_16_1","volume-title":"Global State of Harm Reduction 2018","author":"Stone K","year":"2018"},{"key":"e_1_2_7_17_1","first-page":"1","article-title":"Recommendations for prevention and control of hepatitis C virus (HCV) infection and HCV\u2010related chronic disease","volume":"47","author":"Centers for Disease Control and Prevention","year":"1998","journal-title":"MMWR"},{"key":"e_1_2_7_18_1","first-page":"1","article-title":"Recommendations for the identification of chronic hepatitis C virus infection among persons born during 1945\u20131965","volume":"61","author":"Centers for Disease Control and Prevention","year":"2012","journal-title":"MMWR"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.1123"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12954-018-0230-1"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMsr1912628"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2019.03.011"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(18)30089-X"},{"key":"e_1_2_7_24_1","unstructured":"Rwanda's fight in the elimination of hepatitis C Virus.Website: Rwanda Ministry of Health.https:\/\/www.moh.gov.rw\/news\u2010detail\/rwandas\u2010fight\u2010in\u2010the\u2010elimination\u2010of\u2010hepatitis\u2010c\u2010virus. Accessed January 4 2021."},{"key":"e_1_2_7_25_1","unstructured":"Rwanda National HIV and Viral Hepatitis Annual Report 2017\u20132018. 2019.https:\/\/rbc.gov.rw\/fileadmin\/user_upload\/report2019\/report2019\/Annual%20Report%20for%20HIV%20and%20Viral%20Hepatitis%202017\u20102018.pdf. Accessed January 4 2021."},{"key":"e_1_2_7_26_1","article-title":"Impact of COVID\u201019 on global hepatitis C elimination efforts","author":"Blach S","journal-title":"J Hepatol"}],"container-title":["Liver International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/liv.14779","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/liv.14779","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/liv.14779","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,2]],"date-time":"2023-09-02T23:19:42Z","timestamp":1693696782000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/liv.14779"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1,19]]},"references-count":25,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,3]]}},"alternative-id":["10.1111\/liv.14779"],"URL":"https:\/\/doi.org\/10.1111\/liv.14779","archive":["Portico"],"relation":{},"ISSN":["1478-3223","1478-3231"],"issn-type":[{"value":"1478-3223","type":"print"},{"value":"1478-3231","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,1,19]]},"assertion":[{"value":"2020-11-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-12-28","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-01-19","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}