{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T11:26:31Z","timestamp":1785324391193,"version":"3.55.0"},"reference-count":14,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2021,3,3]],"date-time":"2021-03-03T00:00:00Z","timestamp":1614729600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Liver International"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Data are limited on the epidemiological implications of the recent change in terminology from nonalcoholic fatty liver disease (NAFLD) to metabolic dysfunction\u2010associated fatty liver disease (MAFLD). We therefore performed a cross\u2010sectional study of adults recruited in the 2017\u20102018 National Health and Nutrition Examination Survey, a representative sample of the general US population. The prevalence of NAFLD and MAFLD based on controlled attenuation parameter (CAP) and liver stiffness measurement (LSM) obtained through vibration\u2010controlled transient elastography (VCTE) were 37.1% (95% CI 34.0\u201040.4) and 39.1% (95% CI 36.3\u201042.1), respectively, with higher rates among Hispanic individuals. Agreement between the two definitions was high (Cohen's \u03ba 0.92). Patients with NAFLD and MAFLD also showed similar risk of advanced liver fibrosis (7.5% and 7.4% respectively). Our results suggest that the recent change in diagnostic criteria did not affect the prevalence of the condition in the general United States population.<\/jats:p>","DOI":"10.1111\/liv.14828","type":"journal-article","created":{"date-parts":[[2021,2,16]],"date-time":"2021-02-16T13:14:45Z","timestamp":1613481285000},"page":"1290-1293","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":183,"title":["Prevalence of NAFLD, MAFLD and associated advanced fibrosis in the contemporary United States population"],"prefix":"10.1111","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2422-3041","authenticated-orcid":false,"given":"Stefano","family":"Ciardullo","sequence":"first","affiliation":[{"name":"Department of Medicine and Rehabilitation Policlinico di Monza Monza Italy"},{"name":"Department of Medicine and Surgery University of Milano Bicocca Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3024-0457","authenticated-orcid":false,"given":"Gianluca","family":"Perseghin","sequence":"additional","affiliation":[{"name":"Department of Medicine and Rehabilitation Policlinico di Monza Monza Italy"},{"name":"Department of Medicine and Surgery University of Milano Bicocca Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,3,3]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2020.03.039"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/liv.14548"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2020.10.046"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2019.01.042"},{"key":"e_1_2_10_6_1","unstructured":"National Center for Health Statistics.National Health and Nutrition Examination Survey 2017\u20132018 Laboratory Data. Internet:https:\/\/wwwn.cdc.gov\/nchs\/nhanes\/Search\/DataPage.aspx?Component=Laboratory&CycleBegin(accessed June 2020)."},{"key":"e_1_2_10_7_1","unstructured":"Centers for disease control and prevention.2017: National Health and Nutrition Examination Survey (NHANES). U.S. Department of health and human services. Available fromhttps:\/\/wwwn.cdc.gov\/nchs\/data\/nhanes\/2017\u20102018\/manuals\/2017_MEC_Laboratory_Procedures_Manual.pdfaccessed 31 March 2020."},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.21178"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.21496"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.29367"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2020.08.017"},{"key":"e_1_2_10_12_1","article-title":"Prevalence of obesity and severe obesity among adults: 2017\u20132018","author":"Hales CM","year":"2020","journal-title":"United States"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc20-1778"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/liv.14675"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2018.04.043"}],"container-title":["Liver International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/liv.14828","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/liv.14828","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/liv.14828","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,9]],"date-time":"2025-06-09T11:52:34Z","timestamp":1749469954000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/liv.14828"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,3]]},"references-count":14,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2021,6]]}},"alternative-id":["10.1111\/liv.14828"],"URL":"https:\/\/doi.org\/10.1111\/liv.14828","archive":["Portico"],"relation":{},"ISSN":["1478-3223","1478-3231"],"issn-type":[{"value":"1478-3223","type":"print"},{"value":"1478-3231","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,3,3]]},"assertion":[{"value":"2021-01-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-02-08","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-03-03","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}