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We therefore aimed to examine the prevalence of CD in individuals with AIH.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Two professional librarians searched PubMed, EMBASE, Cochrane and Web of Science Core Collection up until 7 February 2020. The search terms included \u2018celiac disease\u2019, \u2018celiac\u2019, \u2018transglutaminases\u2019, \u2018gluten\u2019, \u2018gliadin\u2019, \u2018EMA\u2019, \u2018TTG\u2019 and \u2018villous\u2019 combined with \u2018autoimmune\u2019, \u2018hepatitis\u2019, \u2018ANA\u2019, \u2018SMA\u2019 and \u2018LKM\u2019. This search yielded 2419 unique publications. A systematic review based on the PRISMA guidelines resulted in 31 articles eligible for full text review. Fifteen articles were deemed relevant, with 8 being included in our main analysis. A fixed\u2010effect inverse variance\u2010weighted model was used, and heterogeneity was calculated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Our main analysis included 567 individuals with AIH from eight studies, where biopsy\u2010verified CD (equivalent to Marsh III) was seen in 23 individuals (4.1%). The <jats:italic>pooled<\/jats:italic> prevalence of CD in AIH was 3.5% (95% CI\u00a0=\u00a01.6%\u20105.3%) (heterogeneity: <jats:italic>P<\/jats:italic>\u00a0=\u00a0.874; <jats:italic>I<\/jats:italic><jats:sup>2<\/jats:sup>\u00a0=\u00a00.0%), which is clearly higher than the 1% CD seen in most general populations. When also including studies where CD had been diagnosed through positive serology without biopsy (15 studies: n\u00a0=\u00a01817 individuals with AIH), the <jats:italic>pooled<\/jats:italic> prevalence of CD was 2.9% (95% CI\u00a0=\u00a02.1%\u20103.8%) (heterogeneity: <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.001; <jats:italic>I<\/jats:italic><jats:sup>2<\/jats:sup>\u00a0=\u00a066.8%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our results demonstrate a higher prevalence of CD in individuals with AIH compared to the general population. CD screening may be considered in patients with AIH.<\/jats:p><\/jats:sec>","DOI":"10.1111\/liv.15000","type":"journal-article","created":{"date-parts":[[2021,7,5]],"date-time":"2021-07-05T07:33:11Z","timestamp":1625470391000},"page":"2693-2702","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":35,"title":["High prevalence of celiac disease in autoimmune hepatitis: Systematic review and meta\u2010analysis"],"prefix":"10.1111","volume":"41","author":[{"given":"Linnea","family":"Hagg\u00e5rd","sequence":"first","affiliation":[{"name":"Department Medical Epidemiology and Biostatistics Karolinska Institutet Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ida","family":"Glimberg","sequence":"additional","affiliation":[{"name":"School of Medical Sciences \u00d6rebro University \u00d6rebro Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Lebwohl","sequence":"additional","affiliation":[{"name":"Celiac Disease Center Department of Medicine Columbia University Medical Center New York NY USA"},{"name":"Department of Epidemiology Mailman School of Public Health Columbia University New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6439-4537","authenticated-orcid":false,"given":"Rajani","family":"Sharma","sequence":"additional","affiliation":[{"name":"Center for Liver Disease and Transplantation Division of Digestive and Liver Diseases Columbia University Irving Medical Center New York NY USA"},{"name":"Division of Digestive and Liver Diseases Department of Medicine Columbia University College of Physicians and Surgeons New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth C.","family":"Verna","sequence":"additional","affiliation":[{"name":"Center for Liver Disease and Transplantation Division of Digestive and Liver Diseases Columbia University Irving Medical Center New York NY USA"},{"name":"Division of Digestive and Liver Diseases Department of Medicine Columbia University College of Physicians and Surgeons New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter H. 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