{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T14:51:36Z","timestamp":1790520696209,"version":"4.1.0"},"reference-count":20,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2021,12,27]],"date-time":"2021-12-27T00:00:00Z","timestamp":1640563200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Liver International"],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>In 2016, Asia and Pacific countries endorsed action plans for reaching viral hepatitis elimination targets set in the Global Health Sector Strategy (GHSS) for Viral Hepatitis 2016\u20102021. We examine the region's progress by modelling disease burden and constructing the cascade of care. Between 2015 and 2020, chronic HBV prevalence declined from 4.69% to 4.30%, and HCV prevalence declined from 0.64% to 0.58%. The region achieved the 2020 target of 30% incidence reduction for HBV, whereas HCV incidence declined by 6%. Hepatocellular carcinoma incidence for HBV and HCV increased by 9% and 7%, respectively. Liver\u2010related deaths from HBV rose by 8%, and mortality attributable to HCV plateaued. Large testing and treatment gaps remained in 2019: only 13% of chronic HBV infections were diagnosed and 25% treated; 21% of chronic HCV infection were diagnosed and 11% treated. Viral hepatitis must become national priority with adequate funding to reach elimination goals by 2030.<\/jats:p>","DOI":"10.1111\/liv.15131","type":"journal-article","created":{"date-parts":[[2021,12,11]],"date-time":"2021-12-11T04:07:25Z","timestamp":1639195645000},"page":"1930-1934","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Progress towards achieving viral hepatitis B and C elimination in the Asia and Pacific region: Results from modelling and global reporting"],"prefix":"10.1111","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5816-7589","authenticated-orcid":false,"given":"Linh\u2010Vi","family":"Le","sequence":"first","affiliation":[{"name":"World Health Organization Regional Office for the Western Pacific  Manila Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9252-7576","authenticated-orcid":false,"given":"Sarah","family":"Blach","sequence":"additional","affiliation":[{"name":"Center for Disease Analysis Foundation  Lafayette Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bharat","family":"Rewari","sequence":"additional","affiliation":[{"name":"World Health Organization Regional Office for South\u2010East Asia  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Polin","family":"Chan","sequence":"additional","affiliation":[{"name":"World Health Organization Regional Office for the Western Pacific  Manila Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cui","family":"Fuqiang","sequence":"additional","affiliation":[{"name":"World Health Organization  Geneva Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoko","family":"Ishikawa","sequence":"additional","affiliation":[{"name":"World Health Organization Regional Office for the Western Pacific  Manila Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mukta","family":"Sharma","sequence":"additional","affiliation":[{"name":"World Health Organization Regional Office for South\u2010East Asia  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nabeel","family":"Mangadan\u2010Konath","sequence":"additional","affiliation":[{"name":"World Health Organization Regional Office for South\u2010East Asia  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Homie","family":"Razavi","sequence":"additional","affiliation":[{"name":"Center for Disease Analysis Foundation  Lafayette Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Low\u2010Beer","sequence":"additional","affiliation":[{"name":"World Health Organization  Geneva Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4135-1053","authenticated-orcid":false,"given":"Devin","family":"Razavi\u2010Shearer","sequence":"additional","affiliation":[{"name":"Center for Disease Analysis Foundation  Lafayette Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,12,27]]},"reference":[{"key":"e_1_2_8_2_1","volume-title":"Accountability for the Global Health Sector Strategies 2016\u20132021: Actions for Impact","year":"2021"},{"key":"e_1_2_8_3_1","volume-title":"Global Health Sector Strategy on Viral Hepatitis 2016\u20132021: Towards Ending Viral Hepatitis","author":"World Health Organization","year":"2016"},{"key":"e_1_2_8_4_1","volume-title":"Regional Action Plan for Viral Hepatitis in the Western Pacific 2016\u20132020: A Priority Action Plan for Awareness, Surveillance, Prevention and Treatment of Viral Hepatitis in the Western Pacific Region","year":"2016"},{"key":"e_1_2_8_5_1","volume-title":"Regional Action Plan for Viral Hepatitis in South\u2010East Asia: 2016\u20132021","year":"2015"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2017.01.006"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2019.114946"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.22898"},{"issue":"28","key":"e_1_2_8_9_1","first-page":"9270","article-title":"Epidemiology and natural history of hepatitis C virus infection","volume":"20","author":"Lee M\u2010H","year":"2014","journal-title":"World J Gastroenterol"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(18)30056-6"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(16)30181-9"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30925-9"},{"key":"e_1_2_8_13_1","unstructured":"Progress report on the Regional Action Plan for viral hepatitis in the WHO South\u2010East Asia Region (2016\u20132021). 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AIDSinfo key population atlas. 2019.https:\/\/kpatlas.unaids.org\/dashboardAccessed July 12 2019)"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(20)30307-1"},{"key":"e_1_2_8_21_1","volume-title":"Guidelines for the Care and Treatment of Persons Diagnosed with Chronic Hepatitis C Virus Infection","year":"2018"}],"container-title":["Liver International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/liv.15131","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/liv.15131","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/liv.15131","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,23]],"date-time":"2023-08-23T15:49:39Z","timestamp":1692805779000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/liv.15131"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,27]]},"references-count":20,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2022,8]]}},"alternative-id":["10.1111\/liv.15131"],"URL":"https:\/\/doi.org\/10.1111\/liv.15131","archive":["Portico"],"relation":{},"ISSN":["1478-3223","1478-3231"],"issn-type":[{"value":"1478-3223","type":"print"},{"value":"1478-3231","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,12,27]]},"assertion":[{"value":"2021-10-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-12-07","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-12-27","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}