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In this case series, we analysed the efficacy and safety of transjugular portosystemic shunt (TIPS) in the treatment of PHT\u2010related complications and its effects on the nutritional status. Six patients were evaluated and the average follow\u2010up period after TIPS was 33 (IQR 5) months. None of the patients developed hepatic failure, nor any recurrence of variceal bleeding was recorded. No additional paracentesis or endoscopic prophylactic treatment for PHT\u2010related complications were required. In all subjects, the average dose of diuretics was almost halved three months after TIPS. Three patients died during the follow\u2010up, but none for liver\u2010related causes. All patients showed an improvement in the global nutritional status. In conclusion, TIPS represent an effective and safe treatment option for patients affected by complications of PHT secondary to HMM and drives to an improvement of the nutritional status.<\/jats:p>","DOI":"10.1111\/liv.15148","type":"journal-article","created":{"date-parts":[[2021,12,28]],"date-time":"2021-12-28T17:58:36Z","timestamp":1640714316000},"page":"419-424","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Portosystemic shunt is an effective treatment for complications of portal hypertension in hepatic myeloid metaplasia and improves nutritional status"],"prefix":"10.1111","volume":"42","author":[{"given":"Silvia","family":"Aspite","sequence":"first","affiliation":[{"name":"Department of Experimental and Clinical Medicine University of Florence Florence 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