{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T19:48:34Z","timestamp":1789069714168,"version":"build-2803163510"},"reference-count":31,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,1,17]],"date-time":"2022-01-17T00:00:00Z","timestamp":1642377600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100006483","name":"AbbVie","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006483","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Liver International"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and aims<\/jats:title><jats:p>Non\u2010O blood group promotes deep vein thrombosis and liver fibrosis in both general population and hepatitis C. We aimed to evaluate the influence of Non\u2010O group on the outcome of Child\u2010Pugh A cirrhotic patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We used two prospective cohorts of Child\u2010Pugh A cirrhosis due to either alcohol or viral hepatitis. Primary end point was the cumulated incidence of \u2018Decompensation\u2019 at 3\u00a0years, defined as the occurrence of ascites , hydrothorax, encephalopathy, gastrointestinal bleeding related to portal hypertension, or bilirubin &gt;45\u00a0\u03bcmol\/L. Secondary end points were the cumulated incidences of (1) \u2018Disease Progression\u2019 including a \u00ab decompensation\u00bb or \u00ab the occurrence of one or more parameters \u00bb among: prothrombin time (PT) &lt;45%, albumin &lt;28\u00a0g\/L, Child\u2010Pugh worsening (B or C vs A or B, C vs B), hepatorenal syndrome, and hepato\u2010pulmonary syndrome, (2) other events such as non\u2010malignant portal vein thrombosis (nmPVT), and (3) overall survival.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Patients (n\u00a0=\u00a01789; 59.9% Non\u2010O group; 40.1% group O) were followed during a median of 65.4\u00a0months. At 3\u00a0years cumulated incidence of Decompensation was 8.3% in Non\u2010O group and 7.2% in group O (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.27). Cumulated incidence of\u00a0Disease Progression\u00a0was 20.7% in Non\u2010O group and 18.9% in group O (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.26). Cumulated incidence of nmPVT was 2.7% in Non\u2010O group and 2.8% in group O (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.05). At 3\u00a0years overall survival was 92.4% in Non\u2010O group and 93.4% in group O (<jats:italic>P<\/jats:italic>\u00a0=\u00a01).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Non\u2010O group does not influence disease outcome in Child\u2010Pugh A cirrhotic patients.<\/jats:p><jats:p><jats:bold>Clinicals trial number<\/jats:bold> NCT03342170.<\/jats:p><\/jats:sec>","DOI":"10.1111\/liv.15159","type":"journal-article","created":{"date-parts":[[2022,1,13]],"date-time":"2022-01-13T14:56:24Z","timestamp":1642085784000},"page":"1386-1400","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["ABO blood group does not influence Child\u2010Pugh A cirrhosis outcome: An observational study\u00a0from CIRRAL and ANRS CO12 CIRVIR cohorts"],"prefix":"10.1111","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5254-2464","authenticated-orcid":false,"given":"Isabelle","family":"Ollivier\u2010Hourmand","sequence":"first","affiliation":[{"name":"Department of Hepatogastroenterology University Hospital  Caen France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yohann","family":"Repesse","sequence":"additional","affiliation":[{"name":"Hematology Laboratory University Hospital  Caen France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2489-0768","authenticated-orcid":false,"given":"Pierre","family":"Nahon","sequence":"additional","affiliation":[{"name":"AP\u2010HP H\u00f4pital Avicenne  Bobigny France"},{"name":"University Sorbonne Paris Nord  Bobigny France"},{"name":"Inserm UMR\u20101138 \u00ab Functional Genomics of Solid Tumors \u00bb, Centre de Recherche des Cordeliers Universit\u00e9 de Paris  Paris 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