{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T21:22:55Z","timestamp":1790716975300,"version":"4.1.0"},"reference-count":51,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,4,12]],"date-time":"2022-04-12T00:00:00Z","timestamp":1649721600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100014232","name":"Helsedirektoratet","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100014232","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Liver International"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background &amp; Aims<\/jats:title><jats:p>New models of HCV care are needed to reach people who inject drugs (PWID). The primary aim was to evaluate HCV treatment uptake among HCV RNA positive individuals identified by point\u2010of\u2010care (POC) testing and liver disease assessment in a peer\u2010driven decentralized mobile clinic.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This prospective study included consecutive patients assessed in a mobile clinic visiting 32 small towns in Southern Norway from November 2019 to November 2020. The clinic was staffed by a bus driver and a social educator offering POC HCV RNA testing (GeneXpert\u00ae), liver disease staging (FibroScan\u00ae 402) and peer support. Viremic individuals were offered prompt pan\u2010genotypic treatment prescribed by local hospital\u2010employed specialists following a brief telephone assessment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among 296 tested individuals, 102 (34%) were HCV RNA positive (median age 51\u2009years, 77% male, 24% advanced liver fibrosis\/cirrhosis). All participants had a history of injecting drug use, 71% reported past 3\u2009months injecting, and 37% received opioid agonist treatment. Treatment uptake within 6 months following enrolment was achieved in 88%. Treatment uptake was negatively associated with recent injecting (aHR 0.60; 95% CI 0.36\u20130.98), harmful alcohol consumption (aHR 0.44; 95% CI 0.20\u20130.99), and advanced liver fibrosis\/cirrhosis (aHR 0.44; 95% CI 0.25\u20130.80). HCV RNA prevalence increased with age (OR 1.81 per 10\u2010year increase; 95% 1.41\u20132.32), ranging from 3% among those &lt;30\u2009years to 55% among those \u226560\u2009years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>A peer\u2010driven mobile HCV clinic is an effective and feasible model of care that should be considered for broader implementation to reach PWID outside the urban centres.<\/jats:p><\/jats:sec>","DOI":"10.1111\/liv.15266","type":"journal-article","created":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T11:11:38Z","timestamp":1648811498000},"page":"1268-1277","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["Peer support in small towns: A decentralized mobile Hepatitis C virus clinic for people who inject drugs"],"prefix":"10.1111","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5043-5107","authenticated-orcid":false,"given":"H\u00e5vard","family":"Midgard","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases Akershus University Hospital  L\u00f8renskog Norway"},{"name":"Department of Gastroenterology Oslo University Hospital  Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronny","family":"Bj\u00f8rnestad","sequence":"additional","affiliation":[{"name":"ProLAR Nett  S\u00f8gne Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maren","family":"Egeland","sequence":"additional","affiliation":[{"name":"ProLAR Nett  S\u00f8gne Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eivin","family":"Dahl","sequence":"additional","affiliation":[{"name":"ProLAR Nett  S\u00f8gne 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