{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T05:27:02Z","timestamp":1792042022831,"version":"4.4.0"},"reference-count":36,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2022,8,24]],"date-time":"2022-08-24T00:00:00Z","timestamp":1661299200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Liver International"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Viral hepatitis is a major cause of death in Africa. A paucity of community\u2010based studies on the determinants of viral hepatitis in Africa impedes efforts to appropriately target prevention, screening, and treatment interventions. We assessed factors associated with hepatitis B virus (HBV) and hepatitis C virus (HCV) in a semi\u2010urban health district in Cameroon.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a community\u2010based, cross\u2010sectional study from 28 February to 15 May 2021 in the Buea Health District in Buea, Cameroon. We recruited a sample of consenting individuals aged over 15\u2009years old. Participants were surveyed for factors associated with HBV\/HCV and were screened for HBV surface antigen (HBsAg) and HCV antibody using rapid point\u2010of\u2010care tests. We performed univariable and multivariable logistic regression analyses to identify factors associated with HBsAg and HCV seropositivity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We screened 1144 participants (66% female) with a median age of 30\u2009years (IQR: 23\u201344). HBsAg prevalence was 5.7% (95%CI: 4.5\u20137.2%) and HCV seropositivity was 1.9% (95%CI: 1.3\u20132.9%). Three people (0.3%) were seropositive for both HBsAg and HCV antibody. Male sex (adjusted OR [aOR]\u00a0=\u00a02.31; 95%CI: 1.28\u20134.18) and a history of traditional operation or scarification (aOR\u00a0=\u00a02.87; 95%CI: 1.67\u20134.92) were associated with HBsAg. None of the assessed factors was significantly associated with HCV antibody.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Men and participants with a history of traditional operation and scarification had higher odds of HBsAg. We did not observe any associations with HCV seropositivity. Prevention and screening efforts among adults in this setting should prioritize men and those with a history of traditional operation and scarification.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/liv.15390","type":"journal-article","created":{"date-parts":[[2022,8,10]],"date-time":"2022-08-10T01:42:56Z","timestamp":1660095776000},"page":"2396-2402","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Factors associated with hepatitis B and C among adults in Buea, Cameroon: A community\u2010based cross\u2010sectional study"],"prefix":"10.1111","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6565-5193","authenticated-orcid":false,"given":"Nkengeh N.","family":"Tazinkeng","sequence":"first","affiliation":[{"name":"Faculty of Health Sciences, University of Buea  Buea Cameroon"},{"name":"Pan\u2010African Organization for Health, Education and Research  Manchester Missouri USA"},{"name":"Department of Population Health Research, Health Education and Research Organization (HERO)  Buea Cameroon"},{"name":"Division of Gastroenterology Massachusetts General Hospital  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denis G.","family":"Teuwafeu","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences, University of Buea  Buea Cameroon"},{"name":"Department of Internal Medicine Buea Regional Hospital  Buea Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akwi W.","family":"Asombang","sequence":"additional","affiliation":[{"name":"Pan\u2010African Organization for Health, Education and Research  Manchester Missouri USA"},{"name":"Division of Gastroenterology Massachusetts General Hospital  Boston Massachusetts USA"},{"name":"Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valirie N.","family":"Agbor","sequence":"additional","affiliation":[{"name":"Department of Population Health Research, Health Education and Research Organization (HERO)  Buea Cameroon"},{"name":"Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health University of Oxford  Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0462-4596","authenticated-orcid":false,"given":"Seth M.","family":"Bloom","sequence":"additional","affiliation":[{"name":"Pan\u2010African Organization for Health, Education and Research  Manchester Missouri USA"},{"name":"Harvard Medical School  Boston Massachusetts USA"},{"name":"Division of Infectious Diseases Massachusetts General Hospital  Boston Massachusetts USA"},{"name":"Ragon Institute of MGH, MIT and Harvard  Cambridge Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alick N.","family":"Nkhoma","sequence":"additional","affiliation":[{"name":"Pan\u2010African Organization for Health, Education and Research  Manchester Missouri USA"},{"name":"University Hospital of the North Midlands NHS Trust  Stoke\u2010on\u2010Trent UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amir M.","family":"Mohareb","sequence":"additional","affiliation":[{"name":"Harvard Medical School  Boston Massachusetts USA"},{"name":"Division of Infectious Diseases Massachusetts General Hospital  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henry N.","family":"Luma","sequence":"additional","affiliation":[{"name":"Douala General Hospital  Douala Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,8,24]]},"reference":[{"key":"e_1_2_11_2_1","unstructured":"Global hepatitis report 2017 World Health Organization"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(17)30295-9"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-019-4731-7"},{"issue":"3","key":"e_1_2_11_5_1","first-page":"17","article-title":"The status of hepatitis B control in the African region","volume":"27","author":"Breakwell L","year":"2017","journal-title":"Pan Afr Med J"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.virusres.2018.02.016"},{"key":"e_1_2_11_7_1","unstructured":"World Health Organization.Hepatitis C: fact sheet. 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