{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T06:25:49Z","timestamp":1787725549018,"version":"build-2784847793"},"reference-count":26,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,1,18]],"date-time":"2023-01-18T00:00:00Z","timestamp":1674000000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100002711","name":"California Dental Association Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100002711","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005564","name":"Gilead Sciences","doi-asserted-by":"publisher","award":["IN\u2010US\u2010987\u20105738"],"award-info":[{"award-number":["IN\u2010US\u2010987\u20105738"]}],"id":[{"id":"10.13039\/100005564","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Liver International"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background &amp; Aims<\/jats:title>\n                    <jats:p>Chronic infection with hepatitis B and C viruses (HBV &amp; HCV) is a major contributor to liver disease and liver\u2010related mortality in Uzbekistan. There is a need to demonstrate the feasibility of large\u2010scale simplified testing and treatment to implement a national viral hepatitis elimination program.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Thirteen polyclinics were utilized to screen, conduct follow\u2010up biochemical measures and treat chronic HBV and HCV infection in the general adult population. Task shifting and motivational interviewing training allowed nurses to provide rapid screening and general practitioners (GPs) to treat individuals on\u2010site. An electronic medical system tracked individuals through the cascade of care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The use of rapid tests allowed for screening of 60\u2009769 people for HCV and HBV over 6\u00a0months and permitted outdoor testing during the COVID\u201019 pandemic along with COVID testing. 13%\u201314% of individuals were lost to follow\u2010up after the rapid test, and another 62%\u201366% failed to come in for their consultation. One stop testing and treatment did not result in a statistically increase in retention and lack of patient awareness of viral hepatitis was identified as a key factor. Despite training, there were large differences between GPs and patients initiating treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The current study demonstrated the feasibility of large\u2010scale general population screening and task shifting in low\u2010 and middle\u2010income countries. However, such programs need to be proceeded by awareness campaign to minimize loss to follow up. In addition, multiple trainings are needed for GPs to bolster their skills to talk to patients about treatment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/liv.15514","type":"journal-article","created":{"date-parts":[[2023,1,6]],"date-time":"2023-01-06T08:18:20Z","timestamp":1672993100000},"page":"773-784","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Viral hepatitis elimination challenges in low\u2010 and middle\u2010income countries\u2014Uzbekistan Hepatitis Elimination Program (UHEP)"],"prefix":"10.1111","volume":"43","author":[{"given":"Erkin","family":"Musabaev","sequence":"first","affiliation":[{"name":"Research Institute of Virology  Tashkent Uzbekistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0668-1452","authenticated-orcid":false,"given":"Chris","family":"Estes","sequence":"additional","affiliation":[{"name":"Center for Disease Analysis Foundation  Lafayette Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shakhlo","family":"Sadirova","sequence":"additional","affiliation":[{"name":"Research Institute of Virology  Tashkent Uzbekistan"},{"name":"Center for Disease Analysis Foundation  Lafayette Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8235-9786","authenticated-orcid":false,"given":"Shokhista","family":"Bakieva","sequence":"additional","affiliation":[{"name":"Research Institute of Virology  Tashkent Uzbekistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krestina","family":"Brigida","sequence":"additional","affiliation":[{"name":"Research Institute of Virology  Tashkent Uzbekistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rick","family":"Dunn","sequence":"additional","affiliation":[{"name":"Research Institute of Virology  Tashkent Uzbekistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shyamasundaran","family":"Kottilil","sequence":"additional","affiliation":[{"name":"University of Maryland School of Medicine  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Poonam","family":"Mathur","sequence":"additional","affiliation":[{"name":"University of Maryland School of Medicine  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ameer","family":"Abutaleb","sequence":"additional","affiliation":[{"name":"University of Maryland School of Medicine  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2659-1801","authenticated-orcid":false,"given":"Kathryn","family":"Razavi\u2010Shearer","sequence":"additional","affiliation":[{"name":"Center for Disease Analysis Foundation  Lafayette Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7762-532X","authenticated-orcid":false,"given":"Tim","family":"Anstiss","sequence":"additional","affiliation":[{"name":"University of Southampton  Southampton UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bakhodir","family":"Yusupaliev","sequence":"additional","affiliation":[{"name":"Ministry of Health of the Republic of Uzbekistan  Tashkent Uzbekistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2658-6930","authenticated-orcid":false,"given":"Homie","family":"Razavi","sequence":"additional","affiliation":[{"name":"Center for Disease Analysis Foundation  Lafayette Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,1,18]]},"reference":[{"key":"e_1_2_10_2_1","volume-title":"Accountability for the global health sector strategies 2016\u20132021: actions for impact","author":"World Health Organization. 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