{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T17:06:45Z","timestamp":1789578405253,"version":"build-2803163510"},"reference-count":57,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2023,8,7]],"date-time":"2023-08-07T00:00:00Z","timestamp":1691366400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Liver International"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Biliary atresia (BA) remains the number one indication for paediatric liver transplantation (LT) worldwide but is an uncommon indication for older LT recipients. The impact of recent donor allocation changes, pervasive organ shortage and evolving LT practices on the BA LT population is unknown.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We identified patients who underwent LT between January 2010 and December 2021 using the UNOS database. We compared clinical outcomes between patients with BA and those with non\u2010BA cholestatic liver disease. Groups were stratified by age, &lt;12\u2009years (allocated via PELD system) and \u226512\u2009years (allocated via MELD system). Waitlist outcomes were compared using competing\u2010risk regression analysis, graft survival rates were compared using Kaplan\u2013Meier time\u2010to\u2010event analysis and Cox proportional hazards modelling provided adjusted estimates.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      There were 2754 BA LT waitlist additions and 2206 BA LTs (1937 &lt;12\u2009years [younger], 269 \u226512\u2009years [older]). There were no differences in waitlist mortality between BA and non\u2010BA cholestatic patients. Among BA LT recipients, there were 441 (20.0%) living\u2010donor liver transplantations (LDLT) and 611 (27.7%) split deceased\u2010donor LTs. Five\u2010year graft survival was significantly higher among BA versus non\u2010BA cholestatic patients in the older group (88.3% vs. 79.5%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u2009.01) but not younger group (89.3% vs. 89.5%). Among BA LT recipients, improved graft outcomes were associated with LDLT (vs. split LT: HR: 2, 95% CI: 1.03\u20133.91) and higher transplant volume (volume &gt;100 vs. &lt;40 BA LTs: HR: 3.41, 95% CI: 1.87\u20136.2).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Liver transplant outcomes among BA patients are excellent, with LDLT and higher transplant centre volume associated with optimal graft outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/liv.15689","type":"journal-article","created":{"date-parts":[[2023,8,7]],"date-time":"2023-08-07T04:46:34Z","timestamp":1691383594000},"page":"2198-2209","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Biliary atresia and liver transplantation in the United States: A contemporary analysis"],"prefix":"10.1111","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9488-7364","authenticated-orcid":false,"given":"Ahmad","family":"Anouti","sequence":"first","affiliation":[{"name":"Division of Digestive and Liver Diseases UT Southwestern Medical Center  Dallas Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madhukar S.","family":"Patel","sequence":"additional","affiliation":[{"name":"Department of Surgery UT Southwestern Medical Center  Dallas Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6264-2573","authenticated-orcid":false,"given":"Lisa B.","family":"VanWagner","sequence":"additional","affiliation":[{"name":"Division of Digestive and Liver Diseases UT Southwestern Medical Center  Dallas Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2783-5441","authenticated-orcid":false,"given":"William M.","family":"Lee","sequence":"additional","affiliation":[{"name":"Division of Digestive and Liver Diseases UT Southwestern Medical Center  Dallas Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John J.","family":"Fung","sequence":"additional","affiliation":[{"name":"Department of Surgery University of Chicago Medicine Transplant Institute  Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5871-6031","authenticated-orcid":false,"given":"George","family":"Cholankeril","sequence":"additional","affiliation":[{"name":"Section of Gastroenterology and Hepatology, Department of Medicine Baylor College of Medicine  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine S.","family":"Hwang","sequence":"additional","affiliation":[{"name":"Department of Surgery UT Southwestern Medical Center  Dallas Texas 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