{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T10:07:57Z","timestamp":1773050877401,"version":"3.50.1"},"reference-count":32,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,11,27]],"date-time":"2023-11-27T00:00:00Z","timestamp":1701043200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100021171","name":"Basic and Applied Basic Research Foundation of Guangdong Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Liver International"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Aims<\/jats:title><jats:p>The transjugular intrahepatic portosystemic shunt has controversial survival benefits; thus, patient screening should be performed preoperatively. In this study, we aimed to develop a model to predict post\u2010transjugular intrahepatic portosystemic shunt mortality to aid clinical decision making.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 811 patients undergoing transjugular intrahepatic portosystemic shunt from five hospitals were divided into the training and external validation data sets. A modified prediction model of post\u2010transjugular intrahepatic portosystemic shunt mortality (Model<jats:sup>MT<\/jats:sup>) was built after performing logistic regression. To verify the improved performance of Model<jats:sup>MT<\/jats:sup>, we compared it with seven previous models, both in discrimination and calibration. Furthermore, patients were stratified into low\u2010, medium\u2010, high\u2010 and extremely high\u2010risk subgroups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Model<jats:sup>MT<\/jats:sup> demonstrated a satisfying predictive efficiency in both discrimination and calibration, with an area under the curve of .875 in the training set and .852 in the validation set. Compared to previous models (ALBI, BILI\u2010PLT, MELD\u2010Na, MOTS, FIPS, MELD, CLIF\u2010C AD), Model<jats:sup>MT<\/jats:sup> showed superior performance in discrimination by statistical difference in the Delong test, net reclassification improvement and integrated discrimination improvement (all <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.050). Similar results were observed in calibration. Low\u2010, medium\u2010, high\u2010 and extremely high\u2010risk groups were defined by scores of \u2264160, 160\u2013180, 180\u2013200 and\u2009&gt;200, respectively. To facilitate future clinical application, we also built an applet for Model<jats:sup>MT<\/jats:sup>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>We successfully developed a predictive model with improved performance to assist in decision making for transjugular intrahepatic portosystemic shunt according to survival benefits.<\/jats:p><\/jats:sec>","DOI":"10.1111\/liv.15790","type":"journal-article","created":{"date-parts":[[2023,11,28]],"date-time":"2023-11-28T01:18:49Z","timestamp":1701134329000},"page":"472-482","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["A modified model for predicting mortality after transjugular intrahepatic portosystemic shunt: A multicentre study"],"prefix":"10.1111","volume":"44","author":[{"given":"Yujie","family":"Zhao","sequence":"first","affiliation":[{"name":"Zhuhai Interventional Medical Center Zhuhai Hospital Affiliated with Jinan University (Zhuhai People's Hospital)  Zhuhai China"},{"name":"Zhuhai Engineering Technology Research Center of Intelligent Medical Imaging Zhuhai Hospital Affiliated with Jinan University (Zhuhai People's Hospital)  Zhuhai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yang","family":"Yang","sequence":"additional","affiliation":[{"name":"Zhuhai Interventional Medical Center Zhuhai Hospital Affiliated with Jinan University (Zhuhai People's Hospital)  Zhuhai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weifu","family":"Lv","sequence":"additional","affiliation":[{"name":"Division of Life Sciences and Medicine, Interventional Radiology Department, The First Affiliated Hospital of USTC University of Science and Technology of China  Hefei China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siyu","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, School of Public Health Southern Medical University  Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoqiong","family":"Chen","sequence":"additional","affiliation":[{"name":"Zhuhai Interventional Medical Center Zhuhai Hospital Affiliated with Jinan University (Zhuhai People's Hospital)  Zhuhai China"},{"name":"Zhuhai Engineering Technology Research Center of Intelligent Medical Imaging Zhuhai Hospital Affiliated with Jinan University (Zhuhai People's Hospital)  Zhuhai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tao","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Biomedical Engineering Southern Medical University  Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mingsheng","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Interventional Radiology The Third Affiliated Hospital of Sun Yat\u2010sen University  Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taixue","family":"An","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, Nanfang Hospital Southern Medical University  Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chongyang","family":"Duan","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, School of Public Health Southern Medical University  Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiangrong","family":"Yu","sequence":"additional","affiliation":[{"name":"Zhuhai Engineering Technology Research Center of Intelligent Medical Imaging Zhuhai Hospital Affiliated with Jinan University (Zhuhai People's Hospital)  Zhuhai China"},{"name":"Department of Radiology Zhuhai People's Hospital (Zhuhai hospital affiliated with Jinan University)  Zhuhai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiyang","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Radiology, Shenzhen People's Hospital  Shenzhen China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinqiang","family":"Chen","sequence":"additional","affiliation":[{"name":"Zhuhai Interventional Medical Center Zhuhai Hospital Affiliated with Jinan University (Zhuhai People's Hospital)  Zhuhai China"},{"name":"Zhuhai Engineering Technology Research Center of Intelligent Medical Imaging Zhuhai Hospital Affiliated with Jinan University (Zhuhai People's Hospital)  Zhuhai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2665-1608","authenticated-orcid":false,"given":"Junyang","family":"Luo","sequence":"additional","affiliation":[{"name":"Department of Interventional Radiology The Third Affiliated Hospital of Sun Yat\u2010sen University  Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuoling","family":"Zhou","sequence":"additional","affiliation":[{"name":"School of Biomedical Engineering Southern Medical University  Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8720-1267","authenticated-orcid":false,"given":"Ligong","family":"Lu","sequence":"additional","affiliation":[{"name":"Zhuhai Interventional Medical Center Zhuhai Hospital Affiliated with Jinan University (Zhuhai People's Hospital)  Zhuhai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meiyan","family":"Huang","sequence":"additional","affiliation":[{"name":"School of Biomedical Engineering Southern Medical University  Guangzhou China"},{"name":"Guangdong Provincial Key Laboratory of Medical Image Processing Southern Medical University  Guangzhou China"},{"name":"Guangdong Province Engineering Laboratory for Medical Imaging and Diagnostic Technology Southern Medical University  Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sirui","family":"Fu","sequence":"additional","affiliation":[{"name":"Zhuhai Interventional Medical Center Zhuhai Hospital Affiliated with Jinan University (Zhuhai People's Hospital)  Zhuhai China"},{"name":"Zhuhai Engineering Technology Research Center of Intelligent Medical Imaging Zhuhai Hospital Affiliated with Jinan University (Zhuhai People's Hospital)  Zhuhai China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,11,27]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2021.07.018"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2018.03.024"},{"key":"e_1_2_14_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2021.12.022"},{"key":"e_1_2_14_5_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2018.02.023"},{"key":"e_1_2_14_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2013.06.014"},{"key":"e_1_2_14_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2018-317057"},{"key":"e_1_2_14_8_1","doi-asserted-by":"publisher","DOI":"10.1053\/gast.2002.37073"},{"key":"e_1_2_14_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2019-320221"},{"key":"e_1_2_14_10_1","doi-asserted-by":"publisher","DOI":"10.1053\/he.2000.5852"},{"key":"e_1_2_14_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/liv.15236"},{"key":"e_1_2_14_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2006.102764"},{"key":"e_1_2_14_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep4.1654"},{"key":"e_1_2_14_14_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.52.6.879"},{"key":"e_1_2_14_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2021.01.023"},{"key":"e_1_2_14_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aca.2007.05.030"},{"key":"e_1_2_14_17_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2012.10.001"},{"key":"e_1_2_14_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12967-017-1214-8"},{"key":"e_1_2_14_19_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199603143341104"},{"key":"e_1_2_14_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diii.2017.10.008"},{"key":"e_1_2_14_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2010.08.025"},{"key":"e_1_2_14_22_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2017-314634"},{"key":"e_1_2_14_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2018.03.027"},{"key":"e_1_2_14_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diii.2015.05.005"},{"key":"e_1_2_14_25_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2020.09.026"},{"key":"e_1_2_14_26_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v20.i10.2704"},{"key":"e_1_2_14_27_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2007.06.020"},{"key":"e_1_2_14_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.32596"},{"key":"e_1_2_14_29_1","doi-asserted-by":"publisher","DOI":"10.4065\/82.7.864"},{"key":"e_1_2_14_30_1","doi-asserted-by":"publisher","DOI":"10.1373\/clinchem.2015.248625"},{"issue":"2","key":"e_1_2_14_31_1","first-page":"299","article-title":"Jaundice in the adult patient","volume":"69","author":"Roche SP","year":"2004","journal-title":"Am Fam Physician"},{"key":"e_1_2_14_32_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2018.00963"},{"key":"e_1_2_14_33_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI103087"}],"container-title":["Liver International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/liv.15790","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,25]],"date-time":"2024-06-25T08:18:44Z","timestamp":1719303524000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/liv.15790"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11,27]]},"references-count":32,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,2]]}},"alternative-id":["10.1111\/liv.15790"],"URL":"https:\/\/doi.org\/10.1111\/liv.15790","archive":["Portico"],"relation":{},"ISSN":["1478-3223","1478-3231"],"issn-type":[{"value":"1478-3223","type":"print"},{"value":"1478-3231","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,11,27]]},"assertion":[{"value":"2023-04-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-11-05","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-11-27","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}