{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T12:30:39Z","timestamp":1790944239369,"version":"4.1.0"},"reference-count":32,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2024,4,4]],"date-time":"2024-04-04T00:00:00Z","timestamp":1712188800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,4,4]],"date-time":"2024-04-04T00:00:00Z","timestamp":1712188800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000288","name":"Royal Society","doi-asserted-by":"publisher","award":["221\u2009805\/Z\/20\/Z"],"award-info":[{"award-number":["221\u2009805\/Z\/20\/Z"]}],"id":[{"id":"10.13039\/501100000288","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Liver International"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background &amp; Aims<\/jats:title>\n                    <jats:p>There is a need to reduce the screen failure rate (SFR) in metabolic dysfunction\u2010associated steatohepatitis (MASH) clinical trials (MASH+F2\u20103; MASH+F4) and identify people with high\u2010risk MASH (MASH+F2\u20104) in clinical practice. We aimed to evaluate non\u2010invasive tests (NITs) screening approaches for these target conditions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This was an individual participant data meta\u2010analysis for the performance of NITs against liver biopsy for MASH+F2\u20104, MASH+F2\u20103 and MASH+F4. Index tests were the FibroScan\u2010AST (FAST) score, liver stiffness measured using vibration\u2010controlled transient elastography (LSM\u2010VCTE), the fibrosis\u20104 score (FIB\u20104) and the NAFLD fibrosis score (NFS). Area under the receiver operating characteristics curve (AUROC) and thresholds including those that achieved 34% SFR were reported.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We included 2281 unique cases. The prevalence of MASH+F2\u20104, MASH+F2\u20103 and MASH+F4 was 31%, 24% and 7%, respectively. Area under the receiver operating characteristics curves for MASH+F2\u20104 were .78, .75, .68 and .57 for FAST, LSM\u2010VCTE, FIB\u20104 and NFS. Area under the receiver operating characteristics curves for MASH+F2\u20103 were .73, .67, .60, .58 for FAST, LSM\u2010VCTE, FIB\u20104 and NFS. Area under the receiver operating characteristics curves for MASH+F4 were .79, .84, .81, .76 for FAST, LSM\u2010VCTE, FIB\u20104 and NFS. The sequential combination of FIB\u20104 and LSM\u2010VCTE for the detection of MASH+F2\u20103 with threshold of .7 and 3.48, and 5.9 and 20\u2009kPa achieved SFR of 67% and sensitivity of 60%, detecting 15 true positive cases from a theoretical group of 100 participants at the prevalence of 24%.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Sequential combinations of NITs do not compromise diagnostic performance and may reduce resource utilisation through the need of fewer LSM\u2010VCTE examinations.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/liv.15914","type":"journal-article","created":{"date-parts":[[2024,4,4]],"date-time":"2024-04-04T09:31:00Z","timestamp":1712223060000},"page":"1872-1885","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Diagnostic accuracy of non\u2010invasive tests to screen for at\u2010risk\n                    <scp>MASH<\/scp>\n                    \u2014An individual participant data meta\u2010analysis"],"prefix":"10.1111","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1361-4349","authenticated-orcid":false,"given":"Ferenc E.","family":"M\u00f3zes","sequence":"first","affiliation":[{"name":"Division of Cardiovascular Medicine, Radcliffe Department of Medicine, OCMR University of Oxford  Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4024-0933","authenticated-orcid":false,"given":"Jenny A.","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Data Science, Amsterdam UMC University of Amsterdam  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7002-118X","authenticated-orcid":false,"given":"Yasaman","family":"Vali","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Data Science, Amsterdam UMC University of Amsterdam  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanuel A.","family":"Selvaraj","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Radcliffe Department of Medicine, OCMR University of Oxford  Oxford UK"},{"name":"Translational Gastroenterology Unit University of Oxford  Oxford UK"},{"name":"Oxford NIHR Biomedical Research Centre Oxford University Hospitals NHS Foundation Trust and the University of Oxford  Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3272-2695","authenticated-orcid":false,"given":"Arjun N. A.","family":"Jayaswal","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Radcliffe Department of Medicine, OCMR University of Oxford  Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00e9r\u00f4me","family":"Boursier","sequence":"additional","affiliation":[{"name":"Laboratoire HIFIH UPRES EA 3859, SFR ICAT 4208, Universit\u00e9 d'Angers  Angers France"},{"name":"Service d'H\u00e9pato\u2010Gastroent\u00e9rologie et Oncologie Digestive Centre Hospitalier Universitaire d'Angers  Angers France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6414-1951","authenticated-orcid":false,"given":"Victor","family":"de L\u00e9dinghen","sequence":"additional","affiliation":[{"name":"Centre d'Investigation de la Fibrose H\u00e9patique, H\u00f4pital Haut\u2010L\u00e9v\u00eaque Bordeaux University Hospital  Pessac France"},{"name":"INSERM1312, Bordeaux University  Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7918-1956","authenticated-orcid":false,"given":"Monica","family":"Lup\u0219or\u2010Platon","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging Iuliu Ha\u021bieganu University of Medicine and Pharmacy, Regional Institute of Gastroenterology and Hepatology \u201cProf.Dr. Octavian Fodor\u201d  Cluj\u2010Napoca Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4518-5283","authenticated-orcid":false,"given":"Yusuf","family":"Yilmaz","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, School of Medicine Marmara University  Istanbul Turkey"},{"name":"Department of Gastroenterology, School of Medicine Recep Tayyip Erdo\u011fan University  Rize Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9105-5837","authenticated-orcid":false,"given":"Wah\u2010Kheong","family":"Chan","sequence":"additional","affiliation":[{"name":"Gastroenterology and Hepatology Unit, Department of Medicine, Faculty of Medicine University of Malaya  Kuala Lumpur Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjiv","family":"Mahadeva","sequence":"additional","affiliation":[{"name":"Gastroenterology and Hepatology Unit, Department of Medicine, Faculty of Medicine University of Malaya  Kuala Lumpur Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8109-8526","authenticated-orcid":false,"given":"Thomas","family":"Karlas","sequence":"additional","affiliation":[{"name":"Department of Oncology, Gastroenterology, Hepatology, Pulmonology and Infectious Diseases University Hospital Leipzig  Leipzig Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9233-4064","authenticated-orcid":false,"given":"Johannes","family":"Wiegand","sequence":"additional","affiliation":[{"name":"Department of Oncology, Gastroenterology, Hepatology, Pulmonology and Infectious Diseases University Hospital Leipzig  Leipzig Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Shalimar","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology All India Institute of Medical Sciences  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5069-2461","authenticated-orcid":false,"given":"Emmanouil","family":"Tsochatzis","sequence":"additional","affiliation":[{"name":"Sheila Sherlock Liver Unit and UCL Institute for Liver and Digestive Health Royal Free Hospital and University College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Liguori","sequence":"additional","affiliation":[{"name":"Sheila Sherlock Liver Unit and UCL Institute for Liver and Digestive Health Royal Free Hospital and University College London  London UK"},{"name":"Department of Translational Medicine and Surgery Universit\u00e0 Cattolica Del Sacro Cuore  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2215-9410","authenticated-orcid":false,"given":"Vincent Wai\u2010Sun","family":"Wong","sequence":"additional","affiliation":[{"name":"Department of Medicine and Therapeutics The Chinese University of Hong Kong  Hong Kong Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8832-3052","authenticated-orcid":false,"given":"Dae Ho","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Gil Medical Center Gachon University College of Medicine  Incheon Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2911-2917","authenticated-orcid":false,"given":"Adriaan G.","family":"Holleboom","sequence":"additional","affiliation":[{"name":"Department of Vascular Medicine, Amsterdam UMC University of Amsterdam  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0831-527X","authenticated-orcid":false,"given":"Anne\u2010Marieke","family":"van Dijk","sequence":"additional","affiliation":[{"name":"Department of Vascular Medicine, Amsterdam UMC University of Amsterdam  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne Linde","family":"Mak","sequence":"additional","affiliation":[{"name":"Department of Vascular Medicine, Amsterdam UMC University of Amsterdam  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8474-1759","authenticated-orcid":false,"given":"Hannes","family":"Hagstr\u00f6m","sequence":"additional","affiliation":[{"name":"Division of Liver and Pancreatic diseases, Department of Upper GI Karolinska University Hospital  Stockholm Sweden"},{"name":"Department of Medicine, Huddinge Karolinska Institutet  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camilla","family":"Akbari","sequence":"additional","affiliation":[{"name":"Department of Medicine, Huddinge Karolinska Institutet  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masashi","family":"Hirooka","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Metabology Ehime University Graduate School of Medicine  Touon Ehime Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong Hyeon","family":"Lee","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Department of Internal Medicine Seoul National University College of Medicine, Seoul Metropolitan Government Boramae Medical Center  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2926-1007","authenticated-orcid":false,"given":"Won","family":"Kim","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Department of Internal Medicine Seoul National University College of Medicine, Seoul Metropolitan Government Boramae Medical Center  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2390-3400","authenticated-orcid":false,"given":"Takeshi","family":"Okanoue","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Saiseikai Suita Hospital  Suita Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshihide","family":"Shima","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Saiseikai Suita Hospital  Suita Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6263-1436","authenticated-orcid":false,"given":"Atsushi","family":"Nakajima","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Yokohama City University School of Medicine  Yokohama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masato","family":"Yoneda","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Yokohama City University School of Medicine  Yokohama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4374-4507","authenticated-orcid":false,"given":"Paul J.","family":"Thuluvath","sequence":"additional","affiliation":[{"name":"Institute of Digestive Health and Liver Diseases, Mercy Medical Center  Baltimore Maryland USA"},{"name":"Department of Medicine University of Maryland School of Medicine  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng","family":"Li","sequence":"additional","affiliation":[{"name":"Institute of Digestive Health and Liver Diseases, Mercy Medical Center  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4562-9016","authenticated-orcid":false,"given":"Annalisa","family":"Berzigotti","sequence":"additional","affiliation":[{"name":"Department for Visceral Medicine and Surgery Inselspital, Bern University Hospital, University of Bern  Bern Switzerland"},{"name":"Department of Biomedical Research University of Bern  Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuly P.","family":"Mendoza","sequence":"additional","affiliation":[{"name":"Department for Visceral Medicine and Surgery Inselspital, Bern University Hospital, University of Bern  Bern Switzerland"},{"name":"Graduate School for Health Sciences (GHS) University of Bern  Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mazen","family":"Noureddin","sequence":"additional","affiliation":[{"name":"Houston Research Institute, Houston Methodist Hospital  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily","family":"Truong","sequence":"additional","affiliation":[{"name":"Department of Medicine Cedars\u2010Sinai Medical Center  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9line","family":"Fournier\u2010Poizat","sequence":"additional","affiliation":[{"name":"Echosens  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Geier","sequence":"additional","affiliation":[{"name":"Division of Hepatology University Hospital W\u00fcrzburg  W\u00fcrzburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theresa","family":"Tuthill","sequence":"additional","affiliation":[{"name":"Internal Medicine Research Unit Pfizer Inc  Cambridge Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carla","family":"Yunis","sequence":"additional","affiliation":[{"name":"Clinical Development and Operations Global Product Development, Pfizer, Inc  Lake Mary Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Quentin M.","family":"Anstee","sequence":"additional","affiliation":[{"name":"Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University  Newcastle upon Tyne UK"},{"name":"Newcastle NIHR Biomedical Research Centre, Newcastle upon Tyne Hospitals NHS Trust  Newcastle upon Tyne UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8285-2204","authenticated-orcid":false,"given":"Stephen A.","family":"Harrison","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Radcliffe Department of Medicine, OCMR University of Oxford  Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick M.","family":"Bossuyt","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Data Science, Amsterdam UMC University of Amsterdam  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9882-8874","authenticated-orcid":false,"given":"Michael","family":"Pavlides","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Radcliffe Department of Medicine, OCMR University of Oxford  Oxford UK"},{"name":"Translational Gastroenterology Unit University of Oxford  Oxford UK"},{"name":"Oxford NIHR Biomedical Research Centre Oxford University Hospitals NHS Foundation Trust and the University of Oxford  Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,4,4]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aohep.2023.101133"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrgastro.2017.109"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.20701"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/GUTJNL-2020-322786"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.JHEP.2022.01.011"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2020.06.025"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/HEP.29477"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2022.03.026"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(19)30383-8"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.JHEP.2021.11.012"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-71995-8"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(20)30252-1"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/HEP.32145"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(23)00017-1"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2021-324243"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2015.3656"},{"key":"e_1_2_10_18_1","volume-title":"R: A Language and Environment for Statistical Computing","author":"R Core Team","year":"2020"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-12-77"},{"key":"e_1_2_10_20_1","unstructured":"CantyA RipleyB.boot: Bootstrap R (S\u2010Plus) Functions. R package version 1.3\u201024.2019."},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1017\/cbo9780511802843"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2020-322976"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/JMRI.27549"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.14309\/CTG.0000000000000157"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.CGH.2021.09.041"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/JGH.15055"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2023.04.031"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41575-021-00523-4"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41575-021-00477-7"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2019.03.033"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1136\/flgastro-2018-101155"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2005.03.084"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.JHEP.2008.07.039"}],"container-title":["Liver International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/liv.15914","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/liv.15914","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/liv.15914","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T19:06:24Z","timestamp":1772996784000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/liv.15914"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,4]]},"references-count":32,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2024,8]]}},"alternative-id":["10.1111\/liv.15914"],"URL":"https:\/\/doi.org\/10.1111\/liv.15914","archive":["Portico"],"relation":{},"ISSN":["1478-3223","1478-3231"],"issn-type":[{"value":"1478-3223","type":"print"},{"value":"1478-3231","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,4]]},"assertion":[{"value":"2023-03-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-03-17","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-04","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}