{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T06:30:34Z","timestamp":1790231434039,"version":"4.1.0"},"reference-count":20,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2024,4,18]],"date-time":"2024-04-18T00:00:00Z","timestamp":1713398400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2024,4,18]],"date-time":"2024-04-18T00:00:00Z","timestamp":1713398400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Liver International"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Metabolic dysfunction\u2010associated steatotic liver disease (MASLD) is the most common paediatric liver disease. Latinos have high MASLD risk due to 50% prevalence of GG genotype of\n                    <jats:italic>PNPLA3<\/jats:italic>\n                    . Our primary aim was to evaluate associations between dietary carbohydrates\/sugars and liver stiffness in Latino adolescents with obesity. Our secondary aim was to examine effect modification by (a)\n                    <jats:italic>PNPLA3<\/jats:italic>\n                    genotype or (b) liver disease severity. Data were obtained from 114 Latino adolescents with obesity involved in two prior studies. No associations were seen between dietary carbohydrates\/sugars and liver stiffness in the group as a whole. In subjects with GG genotype of\n                    <jats:italic>PNPLA3<\/jats:italic>\n                    , total sugar, fructose, sucrose, and glucose were associated with liver stiffness. Positive relationships between carbohydrate, total sugar, and sucrose and liver stiffness were stronger in those with MASLD and fibrosis compared to those with healthy livers and MASLD without fibrosis.\n                  <\/jats:p>","DOI":"10.1111\/liv.15946","type":"journal-article","created":{"date-parts":[[2024,4,18]],"date-time":"2024-04-18T09:05:28Z","timestamp":1713431128000},"page":"1768-1774","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Associations of dietary sugars with liver stiffness in Latino adolescents with obesity differ on\n                    <scp>PNPLA3<\/scp>\n                    and liver disease severity"],"prefix":"10.1111","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0488-6147","authenticated-orcid":false,"given":"Rachel B.","family":"Schenker","sequence":"first","affiliation":[{"name":"Department of Pediatric Gastroenterology, Hepatology, and Nutrition Children's Hospital Los Angeles  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher J.","family":"Machle","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Saban Research Institute Children's Hospital Los Angeles  Los Angeles California USA"},{"name":"Department of Psychology University of Oregon  Eugene Oregon USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelsey A.","family":"Schmidt","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Saban Research Institute Children's Hospital Los Angeles  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hooman","family":"Allayee","sequence":"additional","affiliation":[{"name":"Departments of Population &amp; Public Health Sciences and Biochemistry &amp; Molecular Medicine University of Southern California  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rohit","family":"Kohli","sequence":"additional","affiliation":[{"name":"Department of Pediatric Gastroenterology, Hepatology, and Nutrition Children's Hospital Los Angeles  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael I.","family":"Goran","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Saban Research Institute Children's Hospital Los Angeles  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,4,18]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/HEP.0000000000000520"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/cld.1027"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0000000000001482"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.2010.30185"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.2337\/db10-0554"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/liv.15322"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.30583"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.23535"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/liv.13661"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2018.20579"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2017.05.043"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijpo.12273"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/nxac046"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.21603"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2009.352"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/nbm.1622"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.00064.2004"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.26905"},{"key":"e_1_2_12_20_1","unstructured":"AMPM \u2013 USDA Automated Multiple\u2010Pass Method: USDA ARS.2024.https:\/\/www.ars.usda.gov\/northeast\u2010area\/beltsville\u2010md\u2010bhnrc\/beltsville\u2010human\u2010nutrition\u2010research\u2010center\/food\u2010surveys\u2010research\u2010group\/docs\/ampm\u2010usda\u2010automated\u2010multiple\u2010pass\u2010method\/"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2022.03.044"}],"container-title":["Liver International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/liv.15946","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/liv.15946","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/liv.15946","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T19:05:56Z","timestamp":1772996756000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/liv.15946"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,18]]},"references-count":20,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2024,8]]}},"alternative-id":["10.1111\/liv.15946"],"URL":"https:\/\/doi.org\/10.1111\/liv.15946","archive":["Portico"],"relation":{},"ISSN":["1478-3223","1478-3231"],"issn-type":[{"value":"1478-3223","type":"print"},{"value":"1478-3231","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,18]]},"assertion":[{"value":"2024-02-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-09","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-18","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}