{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T10:42:27Z","timestamp":1788950547932,"version":"build-2803163510"},"reference-count":48,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2024,7,16]],"date-time":"2024-07-16T00:00:00Z","timestamp":1721088000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Liver International"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Socioeconomic status (SES) is a driver of health disparities and chronic diseases. People with HIV (PWH) are at risk for chronic liver diseases. We evaluated the association between low SES and hepatic outcomes in PWH.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We included PWH from a prospective cohort. SES was assessed by the Pampalon material and social deprivation index to classify the cohort into quintiles of deprivation. Multivariable linear regression was used to investigate associations of material and social deprivation with liver stiffness measurement (LSM) and controlled attenuation parameter (CAP) as markers of hepatic fibrosis and steatosis, respectively. Incidence of outcomes was evaluated through survival analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among the 804 PWH included, 45% and 72% were living in areas of the highest material and social deprivation, respectively. Materially deprived PWH were more frequently female and of non\u2010white ethnicity and had higher prevalence of metabolic comorbidities. After adjustments, material deprivation correlated with increased LSM (<jats:italic>\u03b2<\/jats:italic>\u2009=\u20091.86, 95% CI 0.53\u20133.17) but not with CAP (<jats:italic>\u03b2<\/jats:italic>\u2009=\u20096.47, 95% CI \u22125.55\u201318.49). Patients were observed for a median follow\u2010up of 3.8\u2009years. Incidence of liver\u2010related events was higher in most materially deprived compared to most privileged PWH (hazard ratio 3.03, 95% CI 1.03\u20138.92), while there was no difference in extrahepatic outcomes or all\u2010cause mortality. Social deprivation showed no association with either LSM or clinical outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Living in materially deprived neighbourhoods as a proxy for lower SES, is associated with LSM and liver\u2010related events in PWH. Future strategies should explore mechanisms underlying these relationships and whether enhanced material security improves hepatic outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/liv.16022","type":"journal-article","created":{"date-parts":[[2024,7,16]],"date-time":"2024-07-16T08:20:15Z","timestamp":1721118015000},"page":"2615-2624","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Material deprivation is associated with liver stiffness and liver\u2010related outcomes in people with <scp>HIV<\/scp>"],"prefix":"10.1111","volume":"44","author":[{"given":"Clara","family":"Long","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine, Chronic Viral Illness Service McGill University Health Centre  Montreal Quebec Canada"},{"name":"Division of Gastroenterology and Hepatology, Department of Medicine McGill University Health Centre  Montreal Quebec 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