{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T18:51:59Z","timestamp":1789671119975,"version":"4.0.1"},"reference-count":21,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2024,9,11]],"date-time":"2024-09-11T00:00:00Z","timestamp":1726012800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Liver International"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Aims<\/jats:title><jats:p>Metabolic dysfunction\u2010associated steatotic liver disease (MASLD), in the context of autoimmune hepatitis (AIH) among liver transplantation (LT) candidates or recipients remains poorly understood. This study compares waitlist and post\u2010LT outcomes in patients with MASLD\/AIH to MASLD and AIH alone.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Using the united network organ sharing database (2002\u20132022), we compared waitlist outcomes and post\u2010LT survival among patients with MASLD\/AIH (<jats:italic>n<\/jats:italic>\u2009=\u2009282), AIH (<jats:italic>n<\/jats:italic>\u2009=\u20095812), and MASLD (<jats:italic>n<\/jats:italic>\u2009=\u200933\u2009331). Competing risk, Kaplan Meier estimates and Cox proportional hazard analyses were performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>MASLD\/AIH group had the highest rates of encephalopathy and ascites, and highest MELD scores. MASLD\/AIH patients had higher transplantation incidence (adjusted subdistribution hazard ratio [aSHR] 1.64, 95% CI 1.44\u20131.85; <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001) and lower waitlist removal risk (aSHR .30, 95% CI .20\u2013.44; <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001) compared to MASLD alone. One\u2010year post\u2010LT survival favoured MASLD compared to AIH (patient: 92% vs. 91%, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001; graft: 89% vs. 88%, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001) and MASLD\/AIH (patient: 92% vs. 90%, <jats:italic>p<\/jats:italic>\u2009=\u2009.008; graft: 89% vs. 88%, <jats:italic>p<\/jats:italic>\u2009=\u2009.023). Recipients with MASLD\/AIH showed no significant difference in survival at 10\u2010year post\u2010LT compared to MASLD (patient: 63% vs. 61%, <jats:italic>p<\/jats:italic>\u2009=\u2009.68; graft 60% vs. 59%, <jats:italic>p<\/jats:italic>\u2009=\u2009.83) and AIH (patient: 63% vs. 70%, <jats:italic>p<\/jats:italic>\u2009=\u2009.07; graft: 60% vs. 64%, <jats:italic>p<\/jats:italic>\u2009=\u2009.42).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our study showed that MASLD\/AIH patients demonstrate higher LT incidence and lower dropout rates. Long\u2010term post\u2010LT outcomes did not significantly differ between groups. Further prospective multicenter studies are needed to validate these findings.<\/jats:p><\/jats:sec>","DOI":"10.1111\/liv.16100","type":"journal-article","created":{"date-parts":[[2024,9,11]],"date-time":"2024-09-11T13:48:33Z","timestamp":1726062513000},"page":"3083-3095","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Waitlist and transplant outcomes in patients with metabolic dysfunction\u2010associated steatotic liver disease and autoimmune hepatitis"],"prefix":"10.1111","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4008-9770","authenticated-orcid":false,"given":"Esli","family":"Medina\u2010Morales","sequence":"first","affiliation":[{"name":"Department of Medicine Rutgers New Jersey Medical School  Newark New Jersey USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed","family":"Ismail","sequence":"additional","affiliation":[{"name":"Department of Medicine Rutgers New Jersey Medical School  Newark New Jersey USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ritik M.","family":"Goyal","sequence":"additional","affiliation":[{"name":"Department of Medicine Rutgers New Jersey Medical School  Newark New Jersey USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Marenco\u2010Flores","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Hepatology and Nutrition Beth Israel Deaconess Medical Center  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Behnam","family":"Saberi","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Hepatology and Nutrition Beth Israel Deaconess Medical Center  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5596-864X","authenticated-orcid":false,"given":"Zachary","family":"Fricker","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Hepatology and Nutrition Beth Israel Deaconess Medical Center  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6821-0416","authenticated-orcid":false,"given":"Alan","family":"Bonder","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Hepatology and Nutrition Beth Israel Deaconess Medical Center  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirsh D.","family":"Trivedi","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology Cedars\u2010Sinai Medical Center  Los Angeles California 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