{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T22:12:15Z","timestamp":1790460735971,"version":"4.1.0"},"reference-count":189,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,11,4]],"date-time":"2024-11-04T00:00:00Z","timestamp":1730678400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2024,11,4]],"date-time":"2024-11-04T00:00:00Z","timestamp":1730678400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Liver International"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aims<\/jats:title>\n                    <jats:p>Despite liver transplantation (LT) is considered the optimal treatment for hepatocellular carcinoma (HCC), particularly in patients with impaired liver function, the shortage of donors has forced the application of very restrictive criteria for selecting ideal candidates for whom LT can offer the best outcome. With the evolving LT landscape due to the advent of direct\u2010acting antivirals (DAAs) and the steady increase in donors, major efforts have been made to expand the transplant eligibility criteria for HCC. In addition, the emergence of immune checkpoint inhibitors (ICIs) for the treatment of HCC, with demonstrated efficacy in earlier stages, has revolutionized the therapeutic approach for these patients, and their integration in the setting of LT is challenging. Management of immunological compromise from ICIs, including the wash\u2010out period before LT and post\u2010LT immunosuppression adjustments, is crucial to balance the risk of graft rejection against HCC recurrence. Additionally, the effects of increased immunosuppression on non\u2010hepatic complications must be understood to prevent them from becoming obstacles to long\u2010term OS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and Results<\/jats:title>\n                    <jats:p>In this review, we will evaluate the emerging evidence and its implications for the future of LT in HCC. Addressing these novel challenges and opportunities, while integrating the current clinical evidence with predictive algorithms, would ensure a fair balance between individual patient needs and the overall population benefit in the LT system.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/liv.16142","type":"journal-article","created":{"date-parts":[[2024,11,4]],"date-time":"2024-11-04T06:00:31Z","timestamp":1730700031000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["New Scenarios in Liver Transplantation for Hepatocellular Carcinoma"],"prefix":"10.1111","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0757-7676","authenticated-orcid":false,"given":"Ezequiel","family":"Mauro","sequence":"first","affiliation":[{"name":"Barcelona Clinic Liver Cancer (BCLC) Group, Liver Unit, ICMDM, Hospital Clinic Barcelona, IDIBAPS University of Barcelona  Barcelona Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (CIBERehd)  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1795-2919","authenticated-orcid":false,"given":"Manuel","family":"Rodr\u00edguez\u2010Per\u00e1lvarez","sequence":"additional","affiliation":[{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (CIBERehd)  Madrid Spain"},{"name":"Department of Hepatology and Liver Transplantation, Hospital Universitario Reina Sof\u00eda Universidad de C\u00f3rdoba, IMIBIC, CIBERehd  C\u00f3rdoba Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9164-3671","authenticated-orcid":false,"given":"Antonio","family":"D'Alessio","sequence":"additional","affiliation":[{"name":"Department of Surgery &amp; Cancer, Imperial College London Hammersmith Hospital  London UK"},{"name":"Division of Oncology, Department of Translational Medicine University of Piemonte Orientale  Novara Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1178-4897","authenticated-orcid":false,"given":"Gonzalo","family":"Crespo","sequence":"additional","affiliation":[{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (CIBERehd)  Madrid Spain"},{"name":"Liver Transplant Unit, Liver Unit, ICMDM, Hospital Clinic Barcelona, IDIBAPS University of Barcelona  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9528-2279","authenticated-orcid":false,"given":"Federico","family":"Pi\u00f1ero","sequence":"additional","affiliation":[{"name":"School of Medicine Hospital Universitario Austral, Austral University  Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-7602-5621","authenticated-orcid":false,"given":"Eleonora","family":"De Martin","sequence":"additional","affiliation":[{"name":"AP\u2010HP H\u00f4pital Paul\u2010Brousse, Centre H\u00e9pato\u2010Biliaire, INSERM Unit 1193 Universit\u00e9 Paris\u2010Saclay, FHU Hepatinov  Villejuif France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6024-8479","authenticated-orcid":false,"given":"Jordi","family":"Colmenero","sequence":"additional","affiliation":[{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (CIBERehd)  Madrid Spain"},{"name":"Liver Transplant Unit, Liver Unit, ICMDM, Hospital Clinic Barcelona, IDIBAPS University of Barcelona  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3529-0103","authenticated-orcid":false,"given":"David James","family":"Pinato","sequence":"additional","affiliation":[{"name":"Department of Surgery &amp; Cancer, Imperial College London Hammersmith Hospital  London UK"},{"name":"Division of Oncology, Department of Translational Medicine University of Piemonte Orientale  Novara Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9014-4950","authenticated-orcid":false,"given":"Alejandro","family":"Forner","sequence":"additional","affiliation":[{"name":"Barcelona Clinic Liver Cancer (BCLC) Group, Liver Unit, ICMDM, Hospital Clinic Barcelona, IDIBAPS University of Barcelona  Barcelona Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas (CIBERehd)  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,11,4]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2021.11.018"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-199109000-00005"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aohep.2023.101185"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(99)90002-8"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(11)70175-9"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2007.02138.x"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhepr.2023.100965"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.23332"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2018.06.011"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.28923"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.29557"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2018.02.012"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-018-0047-9"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2021.6781"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0000000000005057"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.16655"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajt.2024.05.001"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199603143341104"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2017.09.025"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(20)30224-2"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.32613"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2024.01.011"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/LVT.0000000000000350"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1097\/CLD.0000000000000158"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1053\/jhep.2001.24563"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.22693"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2014-308513"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/tri.12274"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2009.02783.x"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.24117"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1097\/LVT.0000000000000149"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2021.0954"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2012.05.052"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.28643"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/liv.13417"},{"key":"e_1_2_11_37_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2016.5116"},{"key":"e_1_2_11_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhepr.2022.100445"},{"key":"e_1_2_11_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2016.10.038"},{"key":"e_1_2_11_40_1","doi-asserted-by":"publisher","DOI":"10.1111\/liv.13159"},{"key":"e_1_2_11_41_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0000000000002136"},{"key":"e_1_2_11_42_1","doi-asserted-by":"publisher","DOI":"10.1097\/EDE.0000000000000018"},{"key":"e_1_2_11_43_1","doi-asserted-by":"publisher","DOI":"10.1093\/biostatistics\/kxt059"},{"key":"e_1_2_11_44_1","doi-asserted-by":"publisher","DOI":"10.1002\/sim.4085"},{"key":"e_1_2_11_45_1","article-title":"AFP Score and Metroticket 2.0 Perform Similarly and Could Be Used in a \u201cWithin\u2010ALL\u201d Clinical Decision Tool","volume":"5","author":"Pi\u00f1ero F.","year":"2022","journal-title":"JHEP Reports"},{"key":"e_1_2_11_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2020.03.018"},{"key":"e_1_2_11_47_1","doi-asserted-by":"publisher","DOI":"10.1097\/LVT.0000000000000357"},{"key":"e_1_2_11_48_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.29485"},{"key":"e_1_2_11_49_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000003253"},{"key":"e_1_2_11_50_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e31827743d7"},{"key":"e_1_2_11_51_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-010-0993-4"},{"key":"e_1_2_11_52_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.23706"},{"key":"e_1_2_11_53_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e3182a8607e"},{"key":"e_1_2_11_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2021.06.015"},{"key":"e_1_2_11_55_1","doi-asserted-by":"publisher","DOI":"10.1111\/liv.14736"},{"key":"e_1_2_11_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2021.01.043"},{"key":"e_1_2_11_57_1","doi-asserted-by":"publisher","DOI":"10.1097\/LVT.0000000000000259"},{"key":"e_1_2_11_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2023.08.020"},{"key":"e_1_2_11_59_1","doi-asserted-by":"publisher","DOI":"10.3389\/ti.2023.11648"},{"key":"e_1_2_11_60_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.20526"},{"key":"e_1_2_11_61_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.22412"},{"key":"e_1_2_11_62_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.30879"},{"key":"e_1_2_11_63_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhepr.2021.100331"},{"key":"e_1_2_11_64_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhepr.2023.100702"},{"key":"e_1_2_11_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)30207-1"},{"key":"e_1_2_11_66_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0708857"},{"key":"e_1_2_11_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(23)00961-3"},{"key":"e_1_2_11_68_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2024.42.17_suppl.LBA4008"},{"key":"e_1_2_11_69_1","doi-asserted-by":"publisher","DOI":"10.1056\/EVIDOA2100070"},{"key":"e_1_2_11_70_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1915745"},{"key":"e_1_2_11_71_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2021.11.030"},{"key":"e_1_2_11_72_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annonc.2024.02.005"},{"key":"e_1_2_11_73_1","doi-asserted-by":"publisher","DOI":"10.1097\/HEP.0000000000000466"},{"key":"e_1_2_11_74_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(22)01200-4"},{"key":"e_1_2_11_75_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2017-315485"},{"key":"e_1_2_11_76_1","doi-asserted-by":"publisher","DOI":"10.1136\/jitc-2021-003311"},{"key":"e_1_2_11_77_1","doi-asserted-by":"publisher","DOI":"10.3892\/mmr.2015.4171"},{"key":"e_1_2_11_78_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-40078-8"},{"key":"e_1_2_11_79_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-24-0177"},{"key":"e_1_2_11_80_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2024.42.3_suppl.LBA432"},{"key":"e_1_2_11_81_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annonc.2024.08.2277"},{"key":"e_1_2_11_82_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000000710"},{"key":"e_1_2_11_83_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2024.01.018"},{"key":"e_1_2_11_84_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(15)00198-9"},{"key":"e_1_2_11_85_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(23)01796-8"},{"key":"e_1_2_11_86_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annonc.2024.08.2279"},{"key":"e_1_2_11_87_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-023-02786-7"},{"key":"e_1_2_11_88_1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdz155.216"},{"key":"e_1_2_11_89_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvir.2018.12.607"},{"key":"e_1_2_11_90_1","article-title":"P024 KEYNOTE\u2010937 Trial in Progress: Adjuvant Pembrolizumab for Hepatocellular Carcinoma and Complete Radiologic Response After Surgical Resection or Local Ablation","volume":"70","author":"Goyal L.","year":"2021","journal-title":"Gut"},{"key":"e_1_2_11_91_1","doi-asserted-by":"publisher","DOI":"10.1111\/ctr.12644"},{"key":"e_1_2_11_92_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0000000000002955"},{"key":"e_1_2_11_93_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2019.10.021"},{"key":"e_1_2_11_94_1","doi-asserted-by":"publisher","DOI":"10.1038\/s43018-021-00234-4"},{"key":"e_1_2_11_95_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(21)00427-1"},{"key":"e_1_2_11_96_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(21)00385-X"},{"key":"e_1_2_11_97_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010021\u201026472\u20109"},{"key":"e_1_2_11_98_1","doi-asserted-by":"publisher","DOI":"10.1136\/jitc-2022-004656"},{"key":"e_1_2_11_99_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annonc.2022.07.851"},{"key":"e_1_2_11_100_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(23)00186-9"},{"key":"e_1_2_11_101_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.26443"},{"key":"e_1_2_11_102_1","doi-asserted-by":"publisher","DOI":"10.1097\/LVT.0000000000000013"},{"key":"e_1_2_11_103_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2010.03126.x"},{"key":"e_1_2_11_104_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.27538"},{"key":"e_1_2_11_105_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0000000000002852"},{"key":"e_1_2_11_106_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.13779"},{"key":"e_1_2_11_107_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.23950"},{"key":"e_1_2_11_108_1","doi-asserted-by":"publisher","DOI":"10.1111\/liv.15926"},{"key":"e_1_2_11_109_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2021.01.008"},{"key":"e_1_2_11_110_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.26000"},{"key":"e_1_2_11_111_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.30913"},{"key":"e_1_2_11_112_1","doi-asserted-by":"publisher","DOI":"10.2174\/1871525721666230120155734"},{"key":"e_1_2_11_113_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctrv.2016.12.002"},{"key":"e_1_2_11_114_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41698-018-0056-z"},{"key":"e_1_2_11_115_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2023.1137983"},{"key":"e_1_2_11_116_1","doi-asserted-by":"publisher","DOI":"10.1111\/liv.14941"},{"key":"e_1_2_11_117_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11739-024-03578-8"},{"key":"e_1_2_11_118_1","doi-asserted-by":"publisher","DOI":"10.1002\/phar.2896"},{"key":"e_1_2_11_119_1","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvz026"},{"key":"e_1_2_11_120_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(18)30608-9"},{"key":"e_1_2_11_121_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2022.08.024"},{"key":"e_1_2_11_122_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2024.1309100"},{"key":"e_1_2_11_123_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000001104"},{"key":"e_1_2_11_124_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2023.03.023"},{"key":"e_1_2_11_125_1","doi-asserted-by":"publisher","DOI":"10.1097\/LVT.0000000000000396"},{"key":"e_1_2_11_126_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2023.10.040"},{"key":"e_1_2_11_127_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2024.01.008"},{"key":"e_1_2_11_128_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2021.04.047"},{"key":"e_1_2_11_129_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.32468"},{"key":"e_1_2_11_130_1","doi-asserted-by":"publisher","DOI":"10.1097\/HEP.0000000000000030"},{"key":"e_1_2_11_131_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2022.02.004"},{"key":"e_1_2_11_132_1","doi-asserted-by":"publisher","DOI":"10.1097\/HEP.0000000000001026"},{"key":"e_1_2_11_133_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra2215289"},{"key":"e_1_2_11_134_1","doi-asserted-by":"publisher","DOI":"10.1111\/liv.14366"},{"key":"e_1_2_11_135_1","doi-asserted-by":"publisher","DOI":"10.1111\/liv.14866"},{"key":"e_1_2_11_136_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2018080853"},{"key":"e_1_2_11_137_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41379-018-0186-4"},{"key":"e_1_2_11_138_1","doi-asserted-by":"publisher","DOI":"10.1159\/000455014"},{"key":"e_1_2_11_139_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2023.1221135"},{"key":"e_1_2_11_140_1","doi-asserted-by":"publisher","DOI":"10.1097\/SAP.0b013e3181828141"},{"key":"e_1_2_11_141_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2022.1018458"},{"key":"e_1_2_11_142_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2024.1355812"},{"key":"e_1_2_11_143_1","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2021.0012"},{"key":"e_1_2_11_144_1","doi-asserted-by":"publisher","DOI":"10.1159\/000529023"},{"key":"e_1_2_11_145_1","doi-asserted-by":"publisher","DOI":"10.3390\/curroncol29060341"},{"key":"e_1_2_11_146_1","doi-asserted-by":"publisher","DOI":"10.21037\/jgo-23-634"},{"key":"e_1_2_11_147_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2023.1205997"},{"key":"e_1_2_11_148_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12029-024-01040-8"},{"key":"e_1_2_11_149_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12328-021-01521-4"},{"key":"e_1_2_11_150_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.15617"},{"key":"e_1_2_11_151_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.31234"},{"key":"e_1_2_11_152_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.16448"},{"key":"e_1_2_11_153_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajt.2024.01.007"},{"key":"e_1_2_11_154_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajt.2024.04.007"},{"key":"e_1_2_11_155_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.16965"},{"key":"e_1_2_11_156_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.JHEP.2024.06.042"},{"key":"e_1_2_11_157_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.JHEP.2024.09.003"},{"key":"e_1_2_11_158_1","first-page":"2429","article-title":"Pre\u2010Transplant Immune Checkpoint Inhibitor Use: The Intersection Between Medicine, Surgery and Pharmacy","volume":"24","author":"Salerno D. M.","year":"2024","journal-title":"Journal of Hepatology"},{"key":"e_1_2_11_159_1","article-title":"Maintenance Immunosuppression for Adults Undergoing Liver Transplantation: A Network Meta\u2010Analysis","volume":"3","author":"Rodr\u00edguez\u2010Per\u00e1lvarez M.","year":"2017","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"e_1_2_11_160_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.TP.0000081399.75231.3B"},{"key":"e_1_2_11_161_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.13018"},{"key":"e_1_2_11_162_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.17021"},{"key":"e_1_2_11_163_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e3181896278"},{"key":"e_1_2_11_164_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2013.07.012"},{"key":"e_1_2_11_165_1","doi-asserted-by":"publisher","DOI":"10.1097\/LVT.0000000000000459"},{"key":"e_1_2_11_166_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2012.04140.x"},{"key":"e_1_2_11_167_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0000000000001651"},{"key":"e_1_2_11_168_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21041266"},{"key":"e_1_2_11_169_1","doi-asserted-by":"publisher","DOI":"10.1111\/apt.15253"},{"key":"e_1_2_11_170_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0000000000002270"},{"key":"e_1_2_11_171_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0000000000000965"},{"key":"e_1_2_11_172_1","first-page":"335","article-title":"Effects of Everolimus Plus Minimized Tacrolimus on Kidney Function in Liver Transplantation: REDUCE, a Prospective, Randomized Controlled Study","volume":"114","author":"G\u00f3mez\u2010Bravo M.","year":"2022","journal-title":"Revista Espa\u00f1ola de Enfermedades Digestivas"},{"key":"e_1_2_11_173_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0000000000001438"},{"key":"e_1_2_11_174_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.26298"},{"key":"e_1_2_11_175_1","doi-asserted-by":"publisher","DOI":"10.21037\/tgh.2017.08.07"},{"key":"e_1_2_11_176_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2023.01.030"},{"key":"e_1_2_11_177_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trim.2016.07.002"},{"key":"e_1_2_11_178_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0000000000003196"},{"key":"e_1_2_11_179_1","doi-asserted-by":"publisher","DOI":"10.3350\/cmh.2021.0217"},{"key":"e_1_2_11_180_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0000000000003117"},{"key":"e_1_2_11_181_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers15235593"},{"key":"e_1_2_11_182_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.31769"},{"key":"e_1_2_11_183_1","doi-asserted-by":"publisher","DOI":"10.1111\/ctr.12430"},{"key":"e_1_2_11_184_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0000000000003998"},{"key":"e_1_2_11_185_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms19082357"},{"key":"e_1_2_11_186_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2023.1092401"},{"key":"e_1_2_11_187_1","doi-asserted-by":"publisher","DOI":"10.21037\/jgo.2018.07.05"},{"key":"e_1_2_11_188_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0000000000004425"},{"key":"e_1_2_11_189_1","doi-asserted-by":"publisher","DOI":"10.1097\/HC9.0000000000000430"},{"key":"e_1_2_11_190_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8278(24)01215-7"}],"container-title":["Liver International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/liv.16142","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/liv.16142","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/liv.16142","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T12:35:32Z","timestamp":1772973332000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/liv.16142"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,4]]},"references-count":189,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,4]]}},"alternative-id":["10.1111\/liv.16142"],"URL":"https:\/\/doi.org\/10.1111\/liv.16142","archive":["Portico"],"relation":{},"ISSN":["1478-3223","1478-3231"],"issn-type":[{"value":"1478-3223","type":"print"},{"value":"1478-3231","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,4]]},"assertion":[{"value":"2024-06-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-09","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-11-04","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e16142"}}