{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T07:56:46Z","timestamp":1788681406899,"version":"build-2803163510"},"reference-count":5,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2025,7,29]],"date-time":"2025-07-29T00:00:00Z","timestamp":1753747200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Liver International"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>This commentary addresses the findings of a recent nationwide cohort study on risk factors for liver disease progression in individuals with HIV\u2013HBV coinfection. The study identified smoking, excess body weight and HCV coinfection as important accelerators of hepatic deterioration, while traditional socio\u2010economic markers were not significant; urban residence appeared to be protective. We highlight the likely contributions of specialist resource density, surveillance intensity and multidimensional deprivation metrics in shaping these outcomes. The importance of guideline\u2010based antiretroviral therapy and outreach interventions, including smoking cessation and metabolic syndrome management, is also emphasised to address geographic and socio\u2010economic disparities. Future research should further investigate service utilisation and develop targeted strategies to promote equitable liver health in this vulnerable population.<\/jats:p>","DOI":"10.1111\/liv.70249","type":"journal-article","created":{"date-parts":[[2025,7,29]],"date-time":"2025-07-29T16:22:25Z","timestamp":1753806145000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Socio\u2010Economic and Geographic Factors in Liver Disease Progression Among Individuals With\n                    <scp>HIV<\/scp>\n                    \u2013\n                    <scp>HBV<\/scp>\n                    Coinfection"],"prefix":"10.1111","volume":"45","author":[{"given":"Zhixi","family":"Xiao","sequence":"first","affiliation":[{"name":"The Second Clinical Medical College Wenzhou Medical University  Zhejiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4923-0088","authenticated-orcid":false,"given":"Zhengrui","family":"Li","sequence":"additional","affiliation":[{"name":"Shanghai Jiao Tong University School of Medicine  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-7975-0953","authenticated-orcid":false,"given":"Qingyu","family":"Chen","sequence":"additional","affiliation":[{"name":"The Second Clinical Medical College Wenzhou Medical University  Zhejiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,7,29]]},"reference":[{"key":"e_1_2_1_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/liv.70191"},{"key":"e_1_2_1_7_3_1","doi-asserted-by":"publisher","DOI":"10.14309\/ajg.0000000000000948"},{"key":"e_1_2_1_7_4_1","doi-asserted-by":"publisher","DOI":"10.7448\/IAS.20.1.21426"},{"key":"e_1_2_1_7_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10461-021-03551-y"},{"key":"e_1_2_1_7_6_1","unstructured":"Panel on Antiretroviral Guidelines for Adults and Adolescents Department of Health and Human Services \u201cGuidelines for the Use of Antiretroviral Agents in Adults and Adolescents With HIV \u201d(2025) https:\/\/clinicalinfo.hiv.gov\/sites\/default\/files\/guidelines\/documents\/adult\u2010adolescent\u2010arv\/guidelines\u2010adult\u2010adolescent\u2010arv.pdf."}],"container-title":["Liver International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/liv.70249","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T14:06:59Z","timestamp":1764598019000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/liv.70249"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,29]]},"references-count":5,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2025,9]]}},"alternative-id":["10.1111\/liv.70249"],"URL":"https:\/\/doi.org\/10.1111\/liv.70249","archive":["Portico"],"relation":{},"ISSN":["1478-3223","1478-3231"],"issn-type":[{"value":"1478-3223","type":"print"},{"value":"1478-3231","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,29]]},"assertion":[{"value":"2025-07-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-17","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-29","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70249"}}