{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T00:55:45Z","timestamp":1767920145784,"version":"3.49.0"},"reference-count":33,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T00:00:00Z","timestamp":1754092800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81172145"],"award-info":[{"award-number":["81172145"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81420108020"],"award-info":[{"award-number":["81420108020"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["W2411071"],"award-info":[{"award-number":["W2411071"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Liver International"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aims<\/jats:title>\n                    <jats:p>A recanalisation\u2010specific model for Budd\u2010Chiari syndrome (BCS) is lacking. We aimed to develop a novel score for individual long\u2010term outcome prediction and risk stratification.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Overall, 834 BCS patients undergoing recanalisation (566 received percutaneous transluminal angioplasty alone, and 268 with routine stenting) from January 2010 to May 2019 were included from six Chinese centres. The model was developed using Cox multivariable regression, internally validated through a 1000\u2010times bootstrapped method, and compared its performance with existing BCS prognostic models, like the Clichy score.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      During the median follow\u2010up period of 58.0\u2009months, 44 patients were converted to transjugular intrahepatic portosystemic shunt (TIPS), none underwent orthotopic liver transplantation (OLT)\u00a0and 75 died. The final BCS\u2010Recanalisation score incorporated: variceal bleeding history, degree of ascites, albumin, creatinine, urea, white blood cell count and Ln (alkaline phosphatase). The score outperformed other available models with good discrimination (C\u2010index: 0.74) and calibration in predicting TIPS\u2010free survival in the whole cohort, internal validation and most subgroups. Moreover, patients were categorised as low\u2010risk (BCS\u2010Recanalisation score \u2264\u20092.0), intermediate\u2010risk (2.0\u20132.6) and high\u2010risk (&gt;\u20092.6) groups using X\u2010tile software, with a 5\u2010year TIPS\u2010free survival rate of 92.2% (95% CI: 89.5%\u201395.0%), 84.7% (95% CI: 80.0%\u201390.0%) and 67.8% (95% CI: 59.4%\u201377.5%), respectively (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Significant differences were observed in overall survival, stenting\u2010TIPS\u2010free survival and competing\u2010risk adjusted outcomes (restenosis, symptom recurrence, TIPS conversion) across risk strata.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The BCS\u2010Recanalisation score enables individualised outcome prediction and risk stratification in recanalisation\u2010treated patients with BCS, showing promise for clinical application. Future external validation is required.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/liv.70259","type":"journal-article","created":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T09:06:13Z","timestamp":1754125573000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["A Novel Score for Predicting Long\u2010Term Outcomes in Recanalisation\u2010Treated Patients With Budd\u2010Chiari Syndrome: A Multicentre Study"],"prefix":"10.1111","volume":"45","author":[{"given":"Dongdong","family":"Xia","sequence":"first","affiliation":[{"name":"State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers and National Clinical Research Center for Digestive Diseases, Xijing Hospital of Digestive Diseases Fourth Military Medical University  Xi'an China"},{"name":"Department of Liver Disease and Digestive Interventional Radiology, National Clinical Research Centre for Digestive Diseases and Xijing Hospital of Digestive Diseases Fourth Military Medical University  Xi'an China"},{"name":"Department of Digestive and Peripheral Vascular Interventional Radiology Digestive Diseases Hospital, Xi'an International Medical Center Hospital, Northwest University  Xi'an China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bohan","family":"Luo","sequence":"additional","affiliation":[{"name":"Department of Liver Disease and Digestive Interventional Radiology, National Clinical Research Centre for Digestive Diseases and Xijing Hospital of Digestive Diseases Fourth Military Medical University  Xi'an China"},{"name":"Department of Digestive and Peripheral Vascular Interventional Radiology Digestive Diseases Hospital, Xi'an International Medical Center Hospital, Northwest University  Xi'an China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiuhe","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Liver Disease and Digestive Interventional Radiology, National Clinical Research Centre for Digestive Diseases and Xijing Hospital of Digestive Diseases Fourth Military Medical University  Xi'an China"},{"name":"Department of Cardiology Tangdu Hospital, Fourth Military Medical University  Xi'an China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chunqing","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Shandong Provincial Hospital Affiliated to Shandong University and to Shandong First Medical University  Jinan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kewei","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Vascular and Endovascular Surgery Henan Provincial People's Hospital  Zhengzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mingxing","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery The First Affiliated Hospital of Zhengzhou University  Zhengzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qingyong","family":"Fan","sequence":"additional","affiliation":[{"name":"Department of Interventional Radiology Heze Municipal Hospital  Heze China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiaozheng","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Radiology First Affiliated Hospital of China Medical University  Shenyang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Bai","sequence":"additional","affiliation":[{"name":"Department of Liver Disease and Digestive Interventional Radiology, National Clinical Research Centre for Digestive Diseases and Xijing Hospital of Digestive Diseases Fourth Military Medical University  Xi'an China"},{"name":"Department of Digestive and Peripheral Vascular Interventional Radiology Digestive Diseases Hospital, Xi'an International Medical Center Hospital, Northwest 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Gastroenterology Shandong Provincial Hospital Affiliated to Shandong University and to Shandong First Medical University  Jinan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhengyu","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Liver Disease and Digestive Interventional Radiology, National Clinical Research Centre for Digestive Diseases and Xijing Hospital of Digestive Diseases Fourth Military Medical University  Xi'an China"},{"name":"Department of Digestive and Peripheral Vascular Interventional Radiology Digestive Diseases Hospital, Xi'an International Medical Center Hospital, Northwest University  Xi'an China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jie","family":"Yuan","sequence":"additional","affiliation":[{"name":"Department of Liver Disease and Digestive Interventional Radiology, National Clinical Research Centre for Digestive Diseases and Xijing Hospital of Digestive Diseases Fourth Military 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