{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T14:46:06Z","timestamp":1763045166133,"version":"3.45.0"},"reference-count":30,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T00:00:00Z","timestamp":1760313600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Liver International"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aims<\/jats:title>\n                    <jats:p>A higher waitlist mortality (WLM) due to death or removal for being too sick for liver transplantation (LT) was observed among females, leading to the acceptance of Model for End\u2010stage Liver Disease (MELD) 3.0 for liver allocation. However, there remains a knowledge gap on the role of liver disease aetiology on sex\u2010based waitlist outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We analysed the United Network for Organ Sharing database (2014\u20132022) first LT listings in adults for alcoholic\u2010associated liver disease (ALD), metabolic dysfunction\u2010associated steatohepatitis (MASH), hepatitis C virus (HCV), hepatitis B virus (HBV), chronic cholestatic liver disease (CCLD) and metabolic liver disease (MLD). The cumulative 90\u2010day WLM for each aetiology was compared in females and males using a competing risk model, with receiving LT as the competing event. The Fine\u2013Gray multivariable regression model was utilised to examine variables associated with waitlist outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among 88\u2009747 listed candidates, females were younger (mean age 55.6 vs. 56.1\u2009years), had a higher mean MELD score (20.9 vs. 19.5), and a higher proportion of Karnofsky performance status score (KPSS) &gt;\u200940% (57.7% vs. 50%);\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001 for all. Cumulative 90\u2010day WLM in females and males for ALD was 14.8% and 16%, respectively, with a SHR (95% CI) of 0.92 (0.86\u20130.99). WLM was higher in females for MASH (20.7% vs. 19.4%, 1.08 [1.00\u20131.16]) and for CCLD (15.1% vs. 12.4%, 1.24 [1.08\u20131.42]). Advanced age, diabetes, lower KPSS, and high MELD scores were associated with a higher WLM, while Hispanic race was associated with a lower WLM.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>90\u2010Day waitlist mortality in females is lower for ALD and higher for MASH and CCLD.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/liv.70391","type":"journal-article","created":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T21:15:43Z","timestamp":1760390143000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Waitlist Mortality in Candidates Listed for Liver Transplant in Females Varies by Liver Disease Aetiology"],"prefix":"10.1111","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5781-2697","authenticated-orcid":false,"given":"Chencheng","family":"Xie","sequence":"first","affiliation":[{"name":"Department of Gastroenterology University of South Dakota Sanford School of Medicine  Sioux Falls South Dakota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed","family":"Elfeki","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology University of South Dakota Sanford School of Medicine  Sioux Falls South Dakota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohanad","family":"Awadalla","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine St. Luke's Hospitals  New Bedford Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-1854-4569","authenticated-orcid":false,"given":"Abdellatif","family":"Ismail","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine University of Maryland  Baltimore Maryland USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8561-396X","authenticated-orcid":false,"given":"Juan Pablo","family":"Arab","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology Virginia Commonwealth University  Richmond Virginia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Winston","family":"Dunn","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology University of Kansas  Kansas City Kansas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9313-577X","authenticated-orcid":false,"given":"Zobair","family":"Younossi","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Hepatology and Nutrition Innova Hospital  Fairfax Virginia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-6092-2541","authenticated-orcid":false,"given":"Robert","family":"Wong","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology Stanford University  Palo Alto California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashwani K.","family":"Singal","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Hepatology and Nutrition University of Louisville School of Medicine  Louisville Kentucky 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