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Digital health tools may improve retention in alcohol use disorder (AUD) treatment and enhance health outcomes. This study explores a blended intervention (brief intervention plus a serious game (SG) based on motivational interviewing and cognitive\u2010behavioural therapy) on AUD in patients with ArLD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Randomised, single\u2010blinded controlled trial on patients with recent\u2010onset ArLD and AUD. Brief intervention plus the SG was compared to standard addiction therapy. Primary outcomes were AUD treatment retention and adherence at 6\u2009months. Secondary outcomes included liver disease progression, alcohol use patterns, quality of life, functionality, motivational changes and usability.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Seventy\u2010nine patients (mean age 56, MELD\u2010Na 14) were included. Participants in the intervention arm were three times more likely to remain in treatment at month six than those in the control arm (adjusted odds ratio (aOR) 3.24; 82.9% vs. 47.4% of engagement respectively) and attended 50% more appointments. Effect sizes (Cohen's D) were moderate for adherence at months three and six (0.51\u20130.64). At 6\u2009months, Model for End\u2010Stage Liver Disease Sodium (MELD\u2010Na) scores were lower in the experimental group (12 vs. 16,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Among baseline drinkers, alcohol consumption decreased more in the intervention group at month one (11 vs. 6 Standard Drink Units (SDU)\/day,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.031).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The blended intervention increases engagement with AUD treatment, reduces the amount of consumed alcohol and improves MELD\u2010Na scores. These results support the use of digital tailored interventions for AUD in these patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/liv.70506","type":"journal-article","created":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T12:15:08Z","timestamp":1767615308000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["<scp>MyWayUp<\/scp>\n                    : A Digital Intervention for Alcohol Use Disorder in Patients With Alcohol\u2010Related Liver Disease\u2014Results From an\n                    <scp>RCT<\/scp>"],"prefix":"10.1111","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4291-8007","authenticated-orcid":false,"given":"Clara","family":"Oliveras","sequence":"first","affiliation":[{"name":"Health and Addictions Research Group (Grup de Recerca Emergent), Institut D'investigacions Biom\u00e8diques August Pi I Sunyer (IDIBAPS)  Barcelona Spain"},{"name":"Addictions Unit, 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