{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T22:14:09Z","timestamp":1784067249321,"version":"3.55.0"},"reference-count":28,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T00:00:00Z","timestamp":1777334400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T00:00:00Z","timestamp":1777334400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82302323"],"award-info":[{"award-number":["82302323"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Liver International"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aims<\/jats:title>\n                    <jats:p>Hepatic venous pressure gradient (HVPG) is the gold standard for diagnosing clinically significant portal hypertension in patients with viral\u2010 and alcohol\u2010related cirrhosis, but its accuracy is limited in other aetiologies. This study aimed to evaluate the correlation of portal venous pressure measurements in patients with non\u2010alcoholic, non\u2010viral\u2010related decompensated cirrhosis, using fine\u2010needle puncture (FN\u2010PVP), direct portal vein catheterisation (D\u2010PVP) and wedged hepatic vein balloon occlusion (WHVP).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This study retrospectively included patients from the author's centre who simultaneously underwent FN\u2010PVP, HVPG and transjugular intrahepatic portosystemic shunt (TIPS) placement for variceal bleeding or refractory ascites. The Spearman correlation coefficient (r), linear regression coefficient (R\n                      <jats:sup>2<\/jats:sup>\n                      ), intraclass correlation coefficient (ICC) and the Bland\u2013Altman method were used to assess the correlation and consistency between the pressure measurements obtained by the different methods.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Seventy\u2010one patients were included, all undergoing FN\u2010PVP measurements without procedure\u2010related complications. The correlation and consistency between WHVP and D\u2010PVP were moderate (\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u20090.487, R\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u20090.25), while FN\u2010PVP demonstrated excellent correlation and consistency with D\u2010PVP (\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u20090.945, R\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u20090.914). Similar patterns were observed when comparing HVPG and direct portal pressure gradient (D\u2010PPG), fine\u2010needle portal pressure gradient (FN\u2010PPG) and D\u2010PPG (r: 0.558 vs. 0.918; R\n                      <jats:sup>2<\/jats:sup>\n                      : 0.302 vs. 0.87). In patients without intrahepatic venovenous shunts (IHVS), the correlation and consistency between WHVP and D\u2010PVP showed slight improvement (\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u20090.609, ICCa\u2009=\u20090.523, ICCc\u2009=\u20090.620). Using D\u2010PPG as the benchmark, FN\u2010PPG demonstrated excellent classification accuracy, significantly outperforming HVPG.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In patients with non\u2010alcoholic, non\u2010viral\u2010related PHT, HVPG may underestimate the true PPG, regardless of the presence of IHVS. In contrast, FN\u2010PVP can safely and accurately reflect portal pressure and serves as an effective alternative for direct portal pressure measurement.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/liv.70650","type":"journal-article","created":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T12:12:27Z","timestamp":1777378347000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Ultrasound\u2010Guided Fine\u2010Needle vs. Transjugular Portal Pressure Measurements in Non\u2010Viral, Non\u2010Alcoholic Cirrhosis"],"prefix":"10.1111","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-7586-9661","authenticated-orcid":false,"given":"Rufeng","family":"Chen","sequence":"first","affiliation":[{"name":"Shanghai Institute of Medical Imaging  Shanghai China"},{"name":"Department of Interventional Radiology Zhongshan Hospital, Fudan University  Shanghai China"},{"name":"National Clinical Research 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