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A substantial proportion of patients with alcohol\u2010related hepatocellular carcinoma are diagnosed at an advanced stage, frequently because underlying liver disease has not been previously identified and surveillance has not been implemented. This review summarizes recent epidemiological trends and clinical features of alcohol\u2010related hepatocellular carcinoma, with a particular focus on the high proportion of undiagnosed cirrhosis and the challenges posed by alcohol use disorder, comorbidities and socioeconomic vulnerability. Strengthening collaboration between hepatology and addiction medicine, alongside population\u2010level strategies to reduce alcohol use, will be essential to enhance surveillance uptake and ultimately improve outcomes in alcohol\u2010related hepatocellular carcinoma.<\/jats:p>","DOI":"10.1111\/liv.70923","type":"journal-article","created":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T05:46:47Z","timestamp":1791784007000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Missed Diagnosis in Alcohol\u2010Related Hepatocellular Carcinoma: A Call for Alcohol Consumption and Liver Disease Early Detection"],"prefix":"10.1111","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-5283-1094","authenticated-orcid":false,"given":"Victoria","family":"Mignot","sequence":"first","affiliation":[{"name":"Universit\u00e9 Grenoble Alpes  Grenoble France"},{"name":"Institute for Advanced Biosciences (IAB), Universit\u00e9 Grenoble Alpes, Inserm U1209, CNRS UMR5309  Grenoble France"},{"name":"Service D'h\u00e9pato\u2010Gastroent\u00e9rologie et Oncologie Digestive, CHU Grenoble Alpes, Universit\u00e9 Grenoble Alpes  Grenoble France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-0646-9810","authenticated-orcid":false,"given":"Aurore","family":"Baron","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Grenoble Alpes  Grenoble France"},{"name":"Institute for Advanced Biosciences (IAB), Universit\u00e9 Grenoble Alpes, Inserm U1209, CNRS UMR5309  Grenoble France"},{"name":"Centre Hepato Biliaire, Paul Brousse Hospital Inserm URM 1193, Paris Saclay University  Villejuif France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0928-0048","authenticated-orcid":false,"given":"Thomas","family":"Decaens","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Grenoble Alpes  Grenoble France"},{"name":"Institute for Advanced Biosciences (IAB), Universit\u00e9 Grenoble Alpes, Inserm U1209, CNRS UMR5309  Grenoble France"},{"name":"Service D'h\u00e9pato\u2010Gastroent\u00e9rologie et Oncologie Digestive, CHU Grenoble Alpes, Universit\u00e9 Grenoble Alpes  Grenoble France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6115-8512","authenticated-orcid":false,"given":"Charlotte","family":"Costentin","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Grenoble Alpes  Grenoble France"},{"name":"Institute for Advanced Biosciences (IAB), Universit\u00e9 Grenoble Alpes, Inserm U1209, CNRS UMR5309  Grenoble France"},{"name":"Service D'h\u00e9pato\u2010Gastroent\u00e9rologie et Oncologie Digestive, CHU Grenoble Alpes, Universit\u00e9 Grenoble Alpes  Grenoble France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,11]]},"reference":[{"key":"e_1_2_16_2_1","first-page":"229","article-title":"Global Cancer Statistics 2022: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries","volume":"74","author":"Bray F.","year":"2024","journal-title":"CA: A Cancer Journal for Clinicians"},{"key":"e_1_2_16_3_1","doi-asserted-by":"crossref","first-page":"102446","DOI":"10.1016\/j.jceh.2024.102446","article-title":"Global Epidemiology of Hepatocellular Carcinoma","volume":"15","author":"Singh S. 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