{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,3,25]],"date-time":"2024-03-25T18:09:53Z","timestamp":1711390193332},"reference-count":35,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2013,3,12]],"date-time":"2013-03-12T00:00:00Z","timestamp":1363046400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["LUTS"],"published-print":{"date-parts":[[2014,1]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>Functional and urodynamic (<jats:styled-content style=\"fixed-case\">UDS<\/jats:styled-content>) outcomes of <jats:styled-content style=\"fixed-case\">W<\/jats:styled-content>\u2010configured ileal orthotopic neobladder (<jats:styled-content style=\"fixed-case\">ONB<\/jats:styled-content>) with extramural serosa\u2010lined tunnel uretero\u2010ileal anastomosis are presented<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Consecutive 17 patients undergoing <jats:styled-content style=\"fixed-case\">ONB<\/jats:styled-content> during <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>ecember 2009 to <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>arch 2011 were enrolled. Of these 15 men (bladder cancer 14, tuberculosis 1) with mean age 52.7\u2009\u00b1\u200911.3\u2009years completed the follow\u2010up. Pouch\u2010related quality of life (<jats:styled-content style=\"fixed-case\">PQOL<\/jats:styled-content>) was assessed using a published questionnaire. Uroflowmetry, cystometry\/cystography and urethral\u2010pressure profilometry were done at two follow\u2010up visits at least 3\u2009months apart. Mean follow up 10\u2009\u00b1\u20095\u2009months. Mean length of harvested ileum 48\u2009\u00b1\u20096\u2009cm.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Overall <jats:styled-content style=\"fixed-case\">PQOL<\/jats:styled-content> were similar at both evaluations (55\u2009\u00b1\u200911 and 54\u2009\u00b1\u200915, respectively). During first and second follow\u2010up, maximum flow\u2010rate, voided\u2010volume and post\u2010void residual urine were 11\u2009\u00b1\u20094\u2009<jats:styled-content style=\"fixed-case\">mL\/sec<\/jats:styled-content>, 246\u2009\u00b1\u200999\u2009<jats:styled-content style=\"fixed-case\">mL<\/jats:styled-content> and 68\u2009\u00b1\u200974.9\u2009<jats:styled-content style=\"fixed-case\">mL<\/jats:styled-content> and 10.4\u2009\u00b1\u20094.6\u2009<jats:styled-content style=\"fixed-case\">mL\/sec<\/jats:styled-content>, 234\u2009\u00b1\u2009138\u2009<jats:styled-content style=\"fixed-case\">mL<\/jats:styled-content> and 86\u2009\u00b1\u2009146\u2009<jats:styled-content style=\"fixed-case\">mL<\/jats:styled-content>, respectively. Mean neobladder capacity, compliance, maximum urethral closure\u2010pressure (<jats:styled-content style=\"fixed-case\">MUCP<\/jats:styled-content>) and functional urethral length were 484\u2009\u00b1\u2009244\u2009<jats:styled-content style=\"fixed-case\">mL<\/jats:styled-content>, 50.5\u2009\u00b1\u200949.1\u2009<jats:styled-content style=\"fixed-case\">mL<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">cmH<jats:sub>2<\/jats:sub>O<\/jats:styled-content>, 42\u2009\u00b120\u2009<jats:styled-content style=\"fixed-case\">cmH<jats:sub>2<\/jats:sub>O<\/jats:styled-content> and 22\u2009\u00b1\u200912\u2009<jats:styled-content style=\"fixed-case\">mm<\/jats:styled-content>, and 468\u2009\u00b1\u2009250\u2009<jats:styled-content style=\"fixed-case\">mL<\/jats:styled-content>, 46.4\u2009\u00b1\u200947.5\u2009<jats:styled-content style=\"fixed-case\">mL<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">cmH<jats:sub>2<\/jats:sub>O<\/jats:styled-content>, 52\u2009\u00b1\u200927<jats:styled-content style=\"fixed-case\">cmH<jats:sub>2<\/jats:sub>O<\/jats:styled-content> and 23\u2009\u00b1\u200912\u2009<jats:styled-content style=\"fixed-case\">mm<\/jats:styled-content>, respectively. Patients with smaller pouch (r\u2009=\u20090.828; <jats:italic>P<\/jats:italic>\u2009=\u20090.0001), longer urethral length (r\u2009=\u2009\u22120.392; <jats:italic>P<\/jats:italic>\u2009=\u20090.023) and lesser incontinence (r\u2009=\u20090.429; <jats:italic>P<\/jats:italic>\u2009=\u20090.011) had significantly better <jats:styled-content style=\"fixed-case\">PQOL<\/jats:styled-content>. With continued supervised pelvic\u2010floor rehabilitation, a trend in improvement in hesitancy (<jats:italic>P<\/jats:italic>\u2009=\u20090.058), <jats:styled-content style=\"fixed-case\">MUCP<\/jats:styled-content> (<jats:italic>P<\/jats:italic>\u2009=\u20090.05) and bothersome incontinence (<jats:italic>P<\/jats:italic>\u2009=\u2009<jats:styled-content style=\"fixed-case\">NS<\/jats:styled-content>) was observed. None of the patients had any obstruction or reflux of the upper tracts.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The index <jats:styled-content style=\"fixed-case\">ONB<\/jats:styled-content> has reasonable storage and voiding characteristics but with a rider of nocturnal urinary incontinence.<\/jats:p><\/jats:sec>","DOI":"10.1111\/luts.12014","type":"journal-article","created":{"date-parts":[[2013,3,14]],"date-time":"2013-03-14T00:09:55Z","timestamp":1363219795000},"page":"26-34","source":"Crossref","is-referenced-by-count":1,"title":["Short\u2010Term Functional and Urodynamic Outcome of <scp>W<\/scp>\u2010ileal Orthotopic Neobladder with Serosa\u2010Lined Tunneled Uretero\u2010Ileal Anastomosis"],"prefix":"10.1111","volume":"6","author":[{"given":"Yogesh R.","family":"BARAPATRE","sequence":"first","affiliation":[{"name":"Department of Urology Postgraduate Institute of Medical Education and Research  Chandigarh 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