{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T19:01:17Z","timestamp":1788289277526,"version":"build-2803163510"},"reference-count":17,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2014,7,28]],"date-time":"2014-07-28T00:00:00Z","timestamp":1406505600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["LUTS"],"published-print":{"date-parts":[[2015,9]]},"abstract":"<jats:sec><jats:title>Case<\/jats:title><jats:p>A 73\u2010year\u2010old man with Dukes' C adenocarcinoma of the rectum, <jats:styled-content style=\"fixed-case\">pT3N2bM0<\/jats:styled-content>, stage <jats:styled-content style=\"fixed-case\">IIIB<\/jats:styled-content>, presented with voiding difficulties including poor stream and terminal dribbling for one\u2009month. The patient was under careful surveillance and had no postoperative recurrence. Physical examination revealed a palpable irregular nodular lesion (0.5\u2009\u00d7\u20090.5\u2009cm<jats:sup>2<\/jats:sup>) at the penile\u2010scrotal junction. He underwent urethroscopy, which showed a cauliflower lesion in the pendulous urethra. Transurethral resection was performed and histopathologic and immunochemical staining demonstrated a metastatic moderately differentiated urethral adenocarcinoma from the colorectal primary.<\/jats:p><\/jats:sec><jats:sec><jats:title>Outcome<\/jats:title><jats:p>His voiding disorder improved significantly post\u2010operation and he commenced second\u2010line chemotherapy combined with regional radiotherapy. Follow\u2010up urethrocystoscopy and abdominal computed tomography demonstrated no recurrence or metastatic disease. His tumor marker remained within the normal range for 12\u2009months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Urethral metastasis from primary colon cancer is extremely rare. This disease, with its various atypical presentations, presents a diagnostic challenge to the clinician. In patients with recurrent or persistent lower urinary tract symptoms, further urologic workup including thorough history taking, physical examination, and imaging surveys is warranted.<\/jats:p><\/jats:sec>","DOI":"10.1111\/luts.12069","type":"journal-article","created":{"date-parts":[[2014,7,28]],"date-time":"2014-07-28T10:41:52Z","timestamp":1406544112000},"page":"162-165","source":"Crossref","is-referenced-by-count":7,"title":["Urethral Metastasis from Rectal Adenocarcinoma: A Case Report and Review of the Literature"],"prefix":"10.1111","volume":"7","author":[{"given":"Chun\u2010Feng","family":"CHANG","sequence":"first","affiliation":[{"name":"Division of Urology, Department of Surgery Kaohsiung Armed Forces General Hospital  Kaohsiung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shun\u2010Neng","family":"HSU","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Medicine Tri\u2010Service General Hospital, National Defense 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